Human Oncoviruses and Thoracic Tumors: Understanding the Imaging Findings
Por:
Franquet, T, Franks, TJ, Lee, KS, Marchiori, E, Mazzini, S, Gimenez, A, Johkoh, T, Cho, JH, Galvin, JR
Publicada:
1 may 2022
Resumen:
Approximately 1.4 million virus-induced cancers occur annually, representing roughly 10% of the cancer burden worldwide. Seven oncogenic DNA and RNA viruses (ie, oncoviruses) are implicated in approximately 12%-25% of all human cancers owing to a variety of mechanisms as uncommon consequences of the normal viral life cycle. These seven well-recognized human oncoviruses are Epstein-Barr virus (EBV), human T-lymphotropic virus 1, hepatitis B virus, hepatitis C virus, HIV, human papilloma virus (HPV), and human herpesvirus 8 (HHV-8). Several viruses-namely, EBV, HPV, and Kaposi sarcoma herpesvirus or HHV-8-are increasingly being recognized as being related to HIV and/or AIDS, the growing number of transplant cases, and the use of immunosuppressive therapies. Infectious and inflammatory processes, and the accompanying lymphadenopathy, are great mimickers of human oncovirus-related tumors. Although it is often difficult to differentiate these entities, the associated clinical setting and radiologic findings may provide clues for an accurate diagnosis and appropriate management. Malignant lymphoid lesions are best evaluated with multidetector chest CT. The radiologic findings of these lesions are often nonspecific and are best interpreted in correlation with clinical data and histopathologic findings. (C) RSNA, 2022
Filiaciones:
Franquet, T:
Univ Autonoma Barcelona, Dept Diagnost Radiol, Hosp St Pau, C St Quinti 89, Barcelona 08041, Spain
Franks, TJ:
Joint Pathol Ctr, Dept Pulm & Mediastinal Pathol, Dept Def, Silver Spring, MD USA
Amer Inst Radiol Pathol, Dept Chest Imaging, Silver Spring, MD USA
Lee, KS:
Sungkyunkwan Univ Sch Med SKKU SOM, Samsung ChangWon Hosp, Dept Radiol, Chang Won, Gyeongsangnam D, South Korea
Marchiori, E:
Univ Fed Rio de Janeiro, Dept Radiol, Hosp Univ Clementino Fraga Filho, Rio De Janeiro, Brazil
Mazzini, S:
Univ Autonoma Barcelona, Dept Diagnost Radiol, Hosp St Pau, C St Quinti 89, Barcelona 08041, Spain
Gimenez, A:
Univ Autonoma Barcelona, Dept Diagnost Radiol, Hosp St Pau, C St Quinti 89, Barcelona 08041, Spain
Johkoh, T:
Kansai Rosai Hosp, Dept Radiol, Amagasaki, Hyogo, Japan
Cho, JH:
Sungkyunkwan Univ Sch Med SKKU SOM, Samsung Med Ctr, Dept Pathol, Seoul, South Korea
Galvin, JR:
Univ Maryland, Sch Med, Dept Diagnost Radiol, Baltimore, MD 21201 USA
Univ Maryland, Sch Med, Dept Internal Med, Baltimore, MD 21201 USA
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