Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
Por:
Marti, S, Pajares, V, Morante, F, Ramon, MA, Lara, J, Ferrer, J, Guell, MR
Publicada:
1 oct 2013
Resumen:
BACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxygen delivery (DOD) system and pendant reservoir cannula (PRC), were evaluated in subjects with COPD and interstitial lung disease (ILD). METHODS: A cross-sectional, crossover study included 28 COPD and 31 ILD subjects with oxygen desaturation on the 6-min walk test (average S-pO2 < 88%). Each subject underwent 3 walk tests with DOD, PRC, and continuous oxygen flow by standard nasal cannula (CFNC), in random order, taking average S-pO2 >= 90% as the resaturation criterion. RESULTS: Exercise desaturation was corrected in 79%, 79%, and 86% of COPD subjects with CFNC, DOD, and PRC, respectively, and in 77%, 61%, and 81% of ILD subjects with CFNC, DOD, and PRC, respectively. When compared to CFNC, the oxygen-conserving devices showed similar efficacy, except a lower performance for the DOD in the ILD subjects (P = .01). CONCLUSIONS: Although these oxygen-conserving devices corrected exercise hypoxemia in most COPD and ILD subjects, correction was not achieved in about 20% of the severe COPD subjects, regardless of the device, and in nearly 40% of the ILD subjects with the DOD device. These findings underscore that individualized adjustment of oxygen flow is needed for optimal correction of exercise hypoxemia, especially with a DOD in an ILD patient.
Filiaciones:
Marti, S:
Hosp Univ Vall dHebron, Dept Pulmonol, Barcelona 08035, Spain
Univ Autonoma Barcelona, Dept Med, E-08193 Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp, Madrid, Spain
Pajares, V:
Hosp Santa Creu & Sant Pau, Dept Pulmonol, Barcelona, Spain
Morante, F:
Hosp Santa Creu & Sant Pau, Dept Pulmonol, Barcelona, Spain
Ramon, MA:
Hosp Univ Vall dHebron, Dept Pulmonol, Barcelona 08035, Spain
Univ Autonoma Barcelona, Dept Med, E-08193 Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp, Madrid, Spain
Lara, J:
Univ Autonoma Barcelona, Epidemiol & Biostat Lab, E-08193 Barcelona, Spain
Ferrer, J:
Hosp Univ Vall dHebron, Dept Pulmonol, Barcelona 08035, Spain
Univ Autonoma Barcelona, Dept Med, E-08193 Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp, Madrid, Spain
Guell, MR:
Hosp Santa Creu & Sant Pau, Dept Pulmonol, Barcelona, Spain
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