Secondhand smoke exposure at home: Assessment by biomarkers and airborne markers
Por:
Martinez-Sanchez, JM, Sureda, X, Fu, M, Perez-Ortuno, R, Ballbe, M, Lopez, MJ, Salto, E, Pascual, JA, Fernandez, E
Publicada:
1 ago 2014
Resumen:
Objective: We assessed and characterized the relationship among biomarkers of secondhand smoke (SHS) exposure in non-smokers according to their exposure at home as measured by airborne markers.
Methods: We conducted an observational study on exposure to SHS at home using airborne markers (nicotine and benzene) and biomarkers from the non-smokers living in these homes. We selected 49 non-smoking volunteers from different homes: 25 non-smokers living with at least one smoker and 24 non-smokers living in smoke-free homes. We installed two passive devices to measure nicotine and benzene concentrations in the main room of the house (i.e., the living room). One week later, the researcher returned to the volunteer's home to collect the two devices, obtain saliva and urine samples, and administer a SHS questionnaire.
Results: Salivary and urinary cotinine concentrations highly correlated with air nicotine concentrations measured at the volunteers' homes (r(sp)=0.738 and r(sp)=0.679, respectively). The concentrations of airborne markers of SHS and biomarkers in non-smokers increased with increasing self-reported intensity and duration of SHS exposure at home during the previous week (p < 0.05). The multivariable regression model showed a significant association with nicotine in air at home (beta=0.126, p=0.002 for saliva and beta=0.115, p=0.010 for urine).
Conclusions: Our findings suggest that, even in countries with comprehensive smoke-free legislation, exposure to SHS at home continues to be the main source of exposure for non-smokers who live in non-smoke-free homes. Therefore, public health policies should promote smoke-free homes. (C) 2014 Elsevier Inc. All rights reserved.
Filiaciones:
Martinez-Sanchez, JM:
Inst Catala Oncol, Canc Prevent & Control Program, Tobacco Control Unit, Barcelona 08908, Spain
Inst Invest Biomed Bellvitge IDIBELL, Canc Prevent & Control Grp, Barcelona, Spain
Univ Int Catalunya, Dept Basic Sci, Biostat Unit, Sant Cugat Del Valles, Spain
Sureda, X:
Inst Catala Oncol, Canc Prevent & Control Program, Tobacco Control Unit, Barcelona 08908, Spain
Inst Invest Biomed Bellvitge IDIBELL, Canc Prevent & Control Grp, Barcelona, Spain
Univ Barcelona, Dept Clin Sci, Barcelona, Spain
Fu, M:
Inst Catala Oncol, Canc Prevent & Control Program, Tobacco Control Unit, Barcelona 08908, Spain
Inst Invest Biomed Bellvitge IDIBELL, Canc Prevent & Control Grp, Barcelona, Spain
Univ Barcelona, Dept Clin Sci, Barcelona, Spain
Perez-Ortuno, R:
IMIM Hosp Mar Med Res Inst, Barcelona, Spain
Ballbe, M:
Inst Catala Oncol, Canc Prevent & Control Program, Tobacco Control Unit, Barcelona 08908, Spain
Inst Invest Biomed Bellvitge IDIBELL, Canc Prevent & Control Grp, Barcelona, Spain
Univ Barcelona, Dept Clin Sci, Barcelona, Spain
Hosp Clin Barcelona, Inst Neurosci, Addict Unit, Barcelona, Spain
Lopez, MJ:
Agencia Salut Publ Barcelona, Barcelona, Spain
CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain
Inst Invest Biomed IBB St Pau, Barcelona, Spain
Salto, E:
Minist Hlth Generalitat Catalunya, Hlth Plan Directorate, Barcelona, Spain
Univ Barcelona, Dept Publ Hlth, Barcelona, Spain
Pascual, JA:
IMIM Hosp Mar Med Res Inst, Barcelona, Spain
Univ Pompeu Fabra, Dept Expt & Life Sci, Barcelona, Spain
Fernandez, E:
Inst Catala Oncol, Canc Prevent & Control Program, Tobacco Control Unit, Barcelona 08908, Spain
Inst Invest Biomed Bellvitge IDIBELL, Canc Prevent & Control Grp, Barcelona, Spain
Univ Barcelona, Dept Clin Sci, Barcelona, Spain
|