Characterization of Tako-tsubo Cardiomyopathy in Spain: Results from the RETAKO National Registry
Por:
Gil, IJN, Andres, M, Delia, MA, Sionis, A, Martin, A, Bastante, T, Soriano, JGC, Vicente, JAL, Sucarrats, SG, Flecha, ASG
Publicada:
1 jun 2015
Resumen:
Introduction and aims: The etiology and epidemiology of tako-tsubo cardiomyopathy remain uncertain. The symptoms of this condition are often similar to those of myocardial infarction and, although it usually has a good prognosis, it is not without complications. Our aim was to characterize this disease in our setting using a dedicated registry (Spanish REgistry for TAKOtsubo cardiomyopathy).
Methods: The prospective registry included 202 incident patients in 23 hospitals from 2012 to 2013. The patients' clinical characteristics and analytical, echocardiographic, and imaging results were recorded, as were the events during follow-up. Patients were included when the attending physician considered the case proven, and incidence was calculated relative to the catheterizations requested for a presumptive diagnosis of acute coronary syndrome.
Results: The patients were predominantly women (90%), with a mean age of 70 years, and many had cardiovascular risk factors, such as hypertension (67%), dyslipidemia (41%), diabetes mellitus (15%), and smoking (15%). The incidence of tako-tsubo cardiomyopathy was 1.2%, and there was no clear weekly or seasonal distribution pattern. Chest pain was the predominant symptom, a triggering factor (emotional, physical, or both) was present in 72%, and most patients consulted within the first 6 h after symptom onset. The median duration of hospitalization was 7 days. There were heart failure symptoms in 34.0%, arrhythmia in 26.7%, and 2.4% of patients died.
Conclusions: The incidence of tako-tsubo cardiomyopathy is low. This disease primarily affects postmenopausal women, and occurs after a situation of emotional stress in more than half of affected individuals. It is characterized by anginal pain, shows no seasonal distribution, and has a good prognosis, although it is not without morbidity and mortality. (C) 2014 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
Gil, IJN:
Hosp Clin San Carlos, Inst Cardiovasc, Madrid 28040, Spain
Andres, M:
Hosp Valle De Hebron, Serv Cardiol, Barcelona, Spain
Delia, MA:
Hosp Virgen Macarena, Serv Cardiol, Seville, Spain
Sionis, A:
Hosp Sant Pau, IIB Sant Pau, Serv Cardiol, Unidad Cuidados Intens Cardiol, Barcelona, Spain
Martin, A:
Hosp Univ Salamanca, Serv Cardiol, Salamanca, Spain
Bastante, T:
Hosp Univ Princesa, Serv Cardiol, Madrid, Spain
Soriano, JGC:
Complejo Hosp Univ Albacete, Serv Cardiol, Albacete, Spain
Vicente, JAL:
Hosp Clin Lozano Blesa, Serv Cardiol, Zaragoza, Spain
Sucarrats, SG:
Hosp Arnau Vilanova, Serv Cardiol, Lerida, Spain
Flecha, ASG:
Hosp Univ Canarias, Serv Cardiol, Santa Cruz De Tenerife, Spain
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