Determination of avermectins: A QuEChERS approach to the analysis of food samples
Por:
Rubies, A, Antkowiak, S, Granados, M, Companyo, R, Centrich, F
Publicada:
15 ago 2015
Resumen:
We present a simple method for extracting avermectines from meat, based on a QuEChERS approach followed by liquid chromatography (LC) coupled to triple quadrupole (QqQ) tandem mass spectrometry (MS/MS). The compounds considered are ivermectin, abamectin, emamectin, eprinomectin, doramectin and moxidectin. The new method has been fully validated according to the requirements of European Decision 657/2002/CE (EU, 2002). The method is suitable for the analysis of avermectins at concentration as low as 2.5 mu g kg(-1), and allows high sample throughput. In addition, the detection of avermectins by high resolution mass spectrometry using a quadrupole-Orbritrap (Q-Orbitrap) hybrid instrument has been explored, and the target Selected Ion Monitoring data dependent MS/MS (t-SIM-dd MS/MS) mode has been found to provide excellent performance for residue determination of target analytes. (C) 2015 Elsevier Ltd. All rights reserved.
Filiaciones:
Rubies, A:
Lab Agencia Salut Publ Barcelona, Barcelona 08001, Spain
CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain
Antkowiak, S:
Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland
Granados, M:
Univ Barcelona, Dept Analyt Chem, E-08028 Barcelona, Spain
Companyo, R:
Univ Barcelona, Dept Analyt Chem, E-08028 Barcelona, Spain
Centrich, F:
Lab Agencia Salut Publ Barcelona, Barcelona 08001, Spain
CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain
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