Prevalence of microbiologically-confirmed influenza in patients with influenza-like illness in primary care and clinical and epidemiological characteristics


Por: Moragas, A, Garcia-Sangenis, A, Escudero, AP, Faro, CB, Ibanez, RH, Brotons, C, Vilella, T, Puig, M, Casaponsa, RF, Guerrero, SC, Pera, H, van der Velden, AW, Butler, CC, Llor, C

Publicada: 1 oct 2021
Resumen:
Objectives. We evaluated the prevalence of microbiologically-confirmed influenza infection among patients with influenza-like symptoms and compared the clinical and epidemiological characteristics of patients with and without influenza infection. Methods. Retrospective study of a cohort of patients with influenza-like symptoms from 2016 to 2018 who participated in a clinical trial in thirteen urban primary centres in Catalonia. Different epidemiological data were collected. Patients rated the different symptoms and signs on a Likert scale (absent, little problem, moderate problem and severe problem) and self-reported the measure of health status with the EuroQol visual analogue scale. A nasopharyngeal swab was taken for microbiological isolation of influenza and other microorganisms. Results. A total of 427 patients were included. Microbiologically confirmed influenza was found in 240 patients (56.2%). The percentage of patients with moderate-to-severe cough, muscle aches, tiredness and dizziness was greater among patients with microbiologically confirmed influenza. The self-reported health status was significantly lower among patients with true flu infection (mean of 36.3 +/- 18.2 vs 41.7 +/- 17.8 in patients without influenza; p<0.001). Conclusion. Clinical findings are not particularly useful for confirming or excluding the diagnosis of influenza when intensity is not considered. However, the presence of moderate-to-severe cough, myalgias, tiredness and dizziness along with a poor health status is more common in patients with confirmed flu infection.

Filiaciones:
Moragas, A:
 EAP Jaume I, Tarragona, Spain

Garcia-Sangenis, A:
 Inst Univ Invest Atencio Primaria Jordi Gol IDIAP, Barcelona, Spain

Escudero, AP:
 EAP Concordia, Sabadell, Spain

Faro, CB:
 EAP La Marina, Barcelona, Spain

Ibanez, RH:
 EAP La Marina, Barcelona, Spain

Brotons, C:
 Inst Invest Biomed St Pau IIB St Pau, EAP Sardenya, Barcelona, Spain

Vilella, T:
 Inst Invest Biomed St Pau IIB St Pau, EAP Sardenya, Barcelona, Spain

Puig, M:
 Inst Invest Biomed St Pau IIB St Pau, EAP Sardenya, Barcelona, Spain

Casaponsa, RF:
 EAP 17 Setembre, El Prat De Llobregat, Spain

Guerrero, SC:
 EAP Gavarra, Cornella De Llobregat, Spain

Pera, H:
 Inst Univ Invest Atencio Primaria Jordi Gol IDIAP, Barcelona, Spain

van der Velden, AW:
 Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands

Butler, CC:
 Univ Oxford, Dept Primary Care Hlth Serv, Oxford, England

Llor, C:
 EAP, Via Roma, Barcelona, Spain
ISSN: 02143429
Editorial
SOCIEDAD ESPANOLA QUIMIOTERAPIA, UNIV COMPLUTENSE MADRID, MICROBIOLOGY DEPT, SCHOOL MEDICINE, AVDA COMPLUTENSE S/N, MADRID, 28040, SPAIN, ESP
Tipo de documento: Article
Volumen: 34 Número: 5
Páginas: 468-475
WOS Id: 000747670800008
ID de PubMed: 34118801
imagen Green Published, Bronze, All Open Access, Green

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