Quality of Life in Acromegaly
Por:
Webb, SM, Badia, X
Publicada:
1 ene 2016
Resumen:
Available disease-specific questionnaires like the Acromegaly Quality of Life questionnaire have confirmed that quality of life (QoL) is impaired in acromegaly, especially in active disease. Successful therapy improves QoL, but it may not normalize completely even after endocrine cure; furthermore, there is not always a correlation between growth hormone (GH) and insulin-like growth factor 1 and subjective health perception of QoL. Appearance is the dimension most affected and has the highest impact on the patient's QoL. Worse QoL is associated with the presence of musculoskeletal pain, headache (if only medical therapy, not surgery, has been provided), having required treatment with radiotherapy, being older, of female gender, with a longer disease duration, coexisting diabetes mellitus, a higher BMI or becoming GH deficient after treatment for acromegaly. (C) 2015 S. Karger AG, Basel
Filiaciones:
Webb, SM:
Univ Barcelona, Endocrinol Dept, Barcelona, Spain
Univ Barcelona, Ctr Invest Biomed Red Enfermedades Rara CIBER ER, Dept Med, Hosp St Pau,ISCIII,IIB St Pau,Unidad 747, Barcelona, Spain
Univ Autonoma Barcelona, Bellaterra, Spain
Badia, X:
Univ Barcelona, Fac Farm, E-08028 Barcelona, Spain
Evidera, London, England
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