Detection of mcr-1 colistin resistance gene in polyclonal Escherichia coli isolates in Barcelona, Spain, 2012 to 2015
Por:
Prim, N, Rivera, A, Rodriguez-Navarro, J, Espanol, M, Turbau, M, Coll, P, Mirelis, B
Publicada:
31 mar 2016
Resumen:
Colistin resistance was detected in 53 of 10,011 Escherichia coli (0.5%) by prospective phenotypic testing of consecutive clinical isolates in a single hospital in Barcelona, Spain (2012-15). The mcr-1 gene was retrospectively identified by PCR and sequencing in 15 of 50 available isolates. Each isolate had a unique PFGE pattern except for two. This clonal diversity supports the hypothesis of horizontal dissemination of the mcr-1 gene in the local study population.
Filiaciones:
Prim, N:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Rivera, A:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Rodriguez-Navarro, J:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Espanol, M:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Turbau, M:
Hosp Santa Creu & Sant Pau, Emergency Dept, Barcelona, Spain
Coll, P:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Univ Autonoma Barcelona, E-08193 Barcelona, Spain
Mirelis, B:
Hosp Santa Creu & Sant Pau, Dept Microbiol, Barcelona, Spain
Univ Autonoma Barcelona, E-08193 Barcelona, Spain
Gold
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