SEOM clinical guidelines for the management of germ cell testicular cancer (2016)
Por:
Aparicio, J, Terrasa, J, Duran, I, Germa-Lluch, JR, Girones, R, Gonzalez-Billalabeitia, E, Guma , J, Maroto, P, Pinto, A, Garcia-del-Muro, X
Publicada:
1 dic 2016
Resumen:
Testicular cancer represents the most common malignancy in males aged 15-34 years and is considered a model of curable neoplasm. Maintaining success, reducing treatment burden, and focusing on survivorship are then key objectives. Inguinal orchiectomy is the first recommended maneuver that has both diagnostic and therapeutic aims. Most patients are diagnosed with stage I disease (confined to the testicle). Close surveillance and selective, short-course adjuvant chemotherapy are accepted alternatives for these cases. In patients with more advanced disease (stages II and III), 3-4 courses of cisplatin-based chemotherapy (according to IGCCCG risk classification) followed by the judicious surgical removal of residual masses represent the cornerstone of therapy. Poor-risk patients and those failing a first-line therapy should be referred to specialized tertiary centers. Paclitaxel-based conventional chemotherapy and high-dose chemotherapy plus autologous hematopoietic support can cure a proportion of patients with relapsing or refractory disease.
Filiaciones:
Aparicio, J:
Hosp Univ & Politecn La Fe, Serv Oncol Med, Av Abril Martorell 106, Valencia 46026, Spain
Terrasa, J:
Hosp Univ Son Espases, Palma De Mallorca, Spain
Duran, I:
Univ Seville, Inst Biomed Sevilla, IBiS Hosp, Univ Virgen del Rocio,CSIC, Seville, Spain
Germa-Lluch, JR:
ICO IDIBELL Lhospitalet, Inst Catala Oncol, Barcelona, Spain
Girones, R:
Hosp Lluis Alcanyis, Xativa, Spain
Gonzalez-Billalabeitia, E:
Univ Catolica Murcia UCAM, Hosp Univ Morales Meseguer IMIB, Murcia, Spain
Guma , J:
Hosp Univ St Joan Reus, URV, IISPV, Reus, Spain
Maroto, P:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Pinto, A:
Hosp Univ La Paz, Madrid, Spain
Garcia-del-Muro, X:
ICO IDIBELL Lhospitalet, Inst Catala Oncol, Barcelona, Spain
Green Published
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