The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
Por:
Martin-Sanchez, FJ, Rodriguez-Adrada, E, Mueller, C, Vidan, MT, Christ, M, Peacock, WF, Rizzi, MA, Alquezar, A, Pinera, P, Aragues, PL, Llorens, P, Herrero, P, Jacob, J, Fernandez, C, Miro, O
Publicada:
1 mar 2017
Resumen:
ObjectiveThe objective was to determine the effect of frailty on risk of 30-day mortality in nonseverely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs).
MethodologyThe Frailty-AHF Study is a retrospective analysis of a multicenter, observational, prospective, cohort study (Older-AHF Register). This study included consecutive patients 65 years of age without severe functional dependence or dementia attended for AHF in three Spanish EDs for 4 months. Frailty was defined by frailty phenotype as the presence of three or more domains. Baseline and episode characteristics and 30-day mortality were collected in all the patients.
ResultsA total of 465 patients with a mean (SD) age of 82 (+/- 7) years were included, 283 (61.0%) being female and 225 (51.3%) with severe comorbidity (Charlson index 3). Frailty was present in 169 (36.3%). The rate of 30-day mortality was 7.3%. Frailty adjusted for potential confounding factors was an independent factor associated with 30-day mortality (adjusted hazard ratio=2.5; 95% confidence interval= 1.0 to 6.0; p=0.047).
ConclusionThe presence of frailty is an independent risk factor of 30-day mortality in nonsevere dependent older patients attended with AHF in EDs.
Filiaciones:
Martin-Sanchez, FJ:
Hosp Clin San Carlos IdISSC, Inst Invest Sanitaria, Emergency Dept, Hosp Clin San Carlos, Madrid, Spain
Rodriguez-Adrada, E:
Hosp Clin San Carlos IdISSC, Inst Invest Sanitaria, Emergency Dept, Hosp Clin San Carlos, Madrid, Spain
Mueller, C:
Univ Basel Hosp, Dept Cardiol, Basel, Switzerland
Univ Basel Hosp, CRIB, Basel, Switzerland
Vidan, MT:
Univ Complutense Madrid, Inst Invest IiSGM, Hosp Gen Univ Gregorio Maranon, Dept Geriatr Med, Madrid, Spain
Christ, M:
Paracelsus Med Univ, Dept Emergency & Crit Care Med, Nurnberg, Germany
Peacock, WF:
Baylor Coll Med, Dept Emergency Med, Houston, TX 77030 USA
Rizzi, MA:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Emergency Dept, Barcelona, Spain
Alquezar, A:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Emergency Dept, Barcelona, Spain
Pinera, P:
Hosp Reina Sofia, Emergency Dept, Murcia, Spain
Aragues, PL:
Hosp Reina Sofia, Emergency Dept, Murcia, Spain
Llorens, P:
Univ Miguel Hernandez Alicante, Inst Invest Sanitaria & Biomed Alicante ISABIAL, Hosp Gen Alicante, Emergency Dept,Unit Stay & Hosp Home,Fdn FISABIO, Alicante, Spain
Herrero, P:
Hosp Cent Asturias, Emergency Dept, Oviedo, Asturias, Spain
Jacob, J:
Hosp Univ Bellvitge, Emergency Dept, Barcelona, Spain
Fernandez, C:
Univ Complutense Madrid, Inst Invest Sanitaria, Hosp Clin San Carlos, Dept Prevent Med,Hosp Clin San Carlos IdISSC, Madrid, Spain
Miro, O:
Hosp Clin Barcelona, Emergency Dept, Barcelona, Catalonia, Spain
Inst Recerca Biomad August Pi & Sunyer IDIBAPS, Barcelona, Catalonia, Spain
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