Low-toxicity metallosomes for biomedical applications by self-assembly of organometallic metallosurfactants and phospholipids
Por:
Marin-Garcia, M, Benseny-Cases, N, Camacho, M, Suades, J, Barnadas-Rodriguez, R
Publicada:
4 ago 2017
Resumen:
A new and convenient strategy for the preparation of metallosomes has been developed by mixing organometallic metallosurfactants and phospholipids. These aggregates show the characteristic properties of liposomes (stability upon dilution and low toxicity) and the toxicity is at least ten-fold lower than that of the metallosurfactant aggregates without phospholipids.
Filiaciones:
Marin-Garcia, M:
Univ Autonoma Barcelona, Biophys Unit, Ctr Biophys Studies, Dept Biochem & Mol Biol,Fac Med, Avda Can Domenech, Cerdanyola Del Valles 08193, Spain
Benseny-Cases, N:
ALBA Synchrotron, Carrer Llum 2-26, Cerdanyola Del Valles 08290, Spain
Camacho, M:
Univ Autonoma Barcelona, Lab Angiol Vasc Biol & Inflammat, Inst Biomed Res, Hosp Santa Creu & St Pau, St Antoni Maria Claret 167, Barcelona 08025, Spain
Suades, J:
Univ Autonoma Barcelona, Dept Quim, Edifici C, Cerdanyola Del Valles 08193, Spain
Barnadas-Rodriguez, R:
Univ Autonoma Barcelona, Biophys Unit, Ctr Biophys Studies, Dept Biochem & Mol Biol,Fac Med, Avda Can Domenech, Cerdanyola Del Valles 08193, Spain
Hybrid Gold
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