Prevalence of Electrocardiographic Patterns Associated With Sudden Cardiac Death in the Spanish Population Aged 40 Years or Older. Results of the OFRECE Study
Por:
Garcia, PA, Martin, JJA, Abad, CG, Hernandez, RMJ, Ruigomez, AC, Calle, PT, Varela, CC, Antolin, JS, Muniz, J, Doblas, JJG, Roig, E
Publicada:
1 oct 2017
Resumen:
Introduction and objectives: Some electrocardiographic patterns are associated with an increased risk of sudden cardiac death due to ventricular arrhythmias. There is no information on the prevalence of these patterns in the general population in Spain. The objective of this study was to analyze the prevalence of these patterns and associated clinical and epidemiological factors.
Methods: This subanalysis of the OFRECE study selected a representative sample of the Spanish population aged >= 40 years. We studied the presence or absence of electrocardiographic patterns of Brugada syndrome and QT interval abnormalities. Clinical data and electrocardiograms were available in all participants. Electrocardiograms were evaluated by 2 cardiologists and a third cardiologist was consulted if there was disagreement in the diagnosis. We calculated the weighted prevalence and clinical factors associated with the presence of Brugada-type patterns or QT segment abnormalities.
Results: Overall, 8343 individuals were evaluated (59.2 years, 52.4% female). There were 12 Brugada cases (type 1, 2 cases; type 2, 10 cases; weighted prevalence, 0.13%). For corrected QT (QTc) analysis, we excluded participants with left bundle branch block or without sinus rhythm. Weighted prevalences were as follows: short QTc (< 340 ms) 0.18%, borderline QTc (441-469 ms) 8.33%, long QTc (>= 470 ms criterion) 1.01% and long QTc (>= 480 criterion) 0.42%.
Conclusions: A total of 0.6% to 1.1% of the Spanish population aged >= 40 years has an electrocardiographic pattern associated with a higher risk of sudden death (Brugada syndrome, long QT, or short QT). Full English text available from: www.revespcardiol.org/en (C) 2016 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
Garcia, PA:
Hosp Univ Getafe, Serv Cardiol, Carretera Toledo Km 12-500, Madrid 28905, Spain
Martin, JJA:
Hosp Univ Getafe, Serv Cardiol, Carretera Toledo Km 12-500, Madrid 28905, Spain
Abad, CG:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Hernandez, RMJ:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Ruigomez, AC:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Calle, PT:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Varela, CC:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Antolin, JS:
Hosp Univ Fuenlabrada, Serv Cardiol, Madrid, Spain
Muniz, J:
Univ A Coruna, Inst Univ Ciencias Salud, La Coruna, Spain
Univ A Coruna, Inst Invest Biomed A Coruna INIBIC, La Coruna, Spain
Doblas, JJG:
Hosp Clin Univ Virgen Victoria, Serv Cardiol, Malaga, Spain
Roig, E:
Hosp Santa Creu & Sant Pau, Serv Cardiol, Barcelona, Spain
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