Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
Por:
Parron, I, Barrabeig, I, Alseda, M, Rius, C, Cornejo-Sanchez, T, Jane, M, Perez, C, Guix, S, Dominguez, A, Alvarez, J, Sala, MR, Belver, AI, Rovira, A, Coronas, L, Godoy, P, de Andres, A, de Benito, J, Camprubi, E, Cunille, M, Forns, ML, Moreno-Martinez, A, Razquin, E, Sabate, S, de Simon, M, Soldevila, N, Bartolome, R, Martinez, A, Torner, N, Izquierdo, C, Vileu, RM, Camps, N, Sabate, M, Minguell, S, Carol, M
Publicada:
1 dic 2021
Resumen:
Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were analyzed. Viral loads were estimated. The attack rate (AR) of the outbreaks studied, and the rate ratio (RR) and the odds ratio (OR) and their 95% confidence intervals as measures of association were calculated. The mean cycle thresholds were compared using the t-test for independent means. We included 30 outbreaks (4631 exposed people). The global AR was 25.93%. The RR of residents vs. staff was 2.28 (95% CI 2.0-2.6). The RR between AR in residents with total or severe dependence vs. residents with moderate, low or no-dependence was 1.23 (95% CI 1.05-1.45). The AR were higher in smaller centers than in larger ones (38.47% vs. 19.25% and RR 2; 95% CI 1.82-2.2). GII was responsible for 70% of outbreaks. No association was found between the genogroup and presenting symptoms (OR 0.96; 95% CI 0.41-2.26). Viral loads were higher in symptomatic than in asymptomatic patients (p = 0.001).
Filiaciones:
Parron, I:
Subdireccio Reg Barcelona Dept Salut, Barcelona, Spain
Univ Barcelona, Dept Med, Barcelona, Spain
Barrabeig, I:
Subdireccio Reg Barcelona Dept Salut, Barcelona, Spain
Inst Salud Carlos III, CIBER Epidemiol & Salud Publ, Madrid, Spain
Alseda, M:
Subdireccio Reg Lleida Dept Salut, Lleida, Spain
Rius, C:
Inst Salud Carlos III, CIBER Epidemiol & Salud Publ, Madrid, Spain
Agencia Salut Publ Barcelona, Barcelona, Spain
Cornejo-Sanchez, T:
Vall Hebron Hosp, Dept Microbiol, Barcelona, Spain
Jane, M:
Univ Barcelona, Dept Med, Barcelona, Spain
Inst Salud Carlos III, CIBER Epidemiol & Salud Publ, Madrid, Spain
Subdireccio Gen Vigilancia & Resposta Emergencies, Barcelona, Spain
Guix, S:
Univ Barcelona, Grup Virus Enter, Dept Genet Microbiol & Estadist, Barcelona, Spain
Univ Barcelona, Inst Recerca Nutr & Seguretat Alimentaria INSA UB, Santa Coloma De Gramenet, Spain
Dominguez, A:
Univ Barcelona, Dept Med, Barcelona, Spain
Inst Salud Carlos III, CIBER Epidemiol & Salud Publ, Madrid, Spain
Green Published, gold, Green Submitted
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