Chronic Nodular Prurigo: A European Cross-sectional Study of Patient Perspectives on Therapeutic Goals and Satisfaction
Por:
Pereira, MP, Zeidler, C, Wallengren, J, Halvorsen, JA, Weisshaar, E, Garcovich, S, Misery, L, Brenaut, E, Savk, E, Potekaev, N, Lvov, A, Bobko, S, Szepietowski, JC, Reich, A, Bozek, A, Legat, FJ, Metz, M, Streit, M, Serra-Baldrich, E, Goncalo, M, Storck, M, Nau, T, Hoffmann, V, Steinke, S, Greiwe, I, Dugas, M, Augustin, M, Stander, S, European Prurigo Project Epp Conse
Publicada:
1 feb 2021
Resumen:
Chronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. This questionnaire study examined these issues in 406 patients with chronic nodular prurigo from 15 European dermatological centres. Improvements in itch, skin lesions and sleep were the most important goals. Emollients, topical corticosteroids and antihistamines were the most frequently used treatments, while a minority of patients were prescribed potent medications, such as systemic immunosuppressants and gabapentinoids. Most patients were not satisfied with their previous therapy (56.8%), while 9.8% did not receive any ther apy despite having active disease. A substantial number of respondents (28.7%) considered none of the therapeutic options effective. Although chronic nodular prurigo is a severe disease, most patients were not treat ed with potent systemic drugs, which may contribute to the high levels of dissatisfaction and disbelief in available therapies. Specific guidelines for chronic nodular prurigo and the development of novel therapies are necessary to improve care.
Filiaciones:
Pereira, MP:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Zeidler, C:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Wallengren, J:
Lund Univ, Dept Clin Sci Lund, Dermatol & Venereol, Lund, Sweden
Skane Univ Hosp, Lund, Sweden
Halvorsen, JA:
Univ Oslo, Oslo Univ Hosp, Dept Dermatol, Oslo, Norway
Weisshaar, E:
Heidelberg Univ, Dept Social Med Occupat & Environm Dermatol, Heidelberg, Germany
Garcovich, S:
Univ Cattolica Sacro Cuore, UOC Dermatol, Dipartimento Sci Med & Chirurg, Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy
Misery, L:
Univ Hosp Brest, Dept Dermatol, Brest, France
Brenaut, E:
Univ Hosp Brest, Dept Dermatol, Brest, France
Savk, E:
Adnan Menderes Univ, Dept Dermatol, Aydin, Turkey
Potekaev, N:
Moscow Sci & Pract Ctr Dermatovenereol & Cosmetol, Moscow, Russia
Lvov, A:
Moscow Sci & Pract Ctr Dermatovenereol & Cosmetol, Moscow, Russia
Bobko, S:
Moscow Sci & Pract Ctr Dermatovenereol & Cosmetol, Moscow, Russia
Szepietowski, JC:
Wroclaw Med Univ, Dept Dermatol Venereol & Allergol, Wroclaw, Poland
Reich, A:
Univ Rzeszow, Dept Dermatol, Rzeszow, Poland
Bozek, A:
Univ Informat Technol & Management, Sch Med, Dept Dermatol, Rzeszow, Poland
Legat, FJ:
Med Univ Graz, Dept Dermatol, Graz, Austria
Metz, M:
Charite Univ Med Berlin, Dept Dermatol & Allergy, Berlin, Germany
Streit, M:
Kantonsspital Aarau, Dept Dermatol, Aarau, Switzerland
Serra-Baldrich, E:
St Pau Hosp, Dept Dermatol, Barcelona, Spain
Goncalo, M:
Univ Coimbra, Dept Dermatol, Univ Hosp, Coimbra, Portugal
Univ Coimbra, Fac Med, Coimbra, Portugal
Storck, M:
Univ Munster, Inst Med Informat, Munster, Germany
Nau, T:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Hoffmann, V:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Steinke, S:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Greiwe, I:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
Dugas, M:
Univ Munster, Inst Med Informat, Munster, Germany
Augustin, M:
Univ Hosp Hamburg Eppendorf, Competence Ctr Healthcare Res Dermatol CVderm, Inst Healthcare Res Dermatol & Nursing IVDP, Hamburg, Germany
Stander, S:
Univ Hosp Munster, Dept Dermatol, Von Esmarch Str 58, DE-48149 Munster, Germany
Univ Hosp Munster, Ctr Chron Pruritus, Von Esmarch Str 58, DE-48149 Munster, Germany
gold, Green Published
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