Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Por: Chia, R, Sabir, MS, Bandres-Ciga, S, Saez-Atienzar, S, Reynolds, RH, Gustavsson, E, Walton, RL, Ahmed, S, Viollet, C, Ding, JH, Makarious, MB, Diez-Fairen, M, Portley, MK, Shah, Z, Abramzon, Y, Hernandez, DG, Blauwendraat, C, Stone, DJ, Eicher, J, Parkkinen, L, Ansorge, O, Clark, L, Honig, LS, Marder, K, Lemstra, A, St George-Hyslop, P, Londos, E, Morgan, K, Lashley, T, Warner, TT, Jaunmuktane, Z, Galasko, D, Santana, I, Tienari, PJ, Myllykangas, L, Oinas, M, Cairns, NJ, Morris, JC, Halliday, GM, Van Deerlin, VM, Trojanowski, JQ, Grassano, M, Calvo, A, Mora, G, Canosa, A, Floris, G, Bohannan, RC, Brett, F, Gan-Or, Z, Geiger, JT, Moore, A, May, P, Kruger, R, Goldstein, DS, Lopez, G, Tayebi, N, Sidransky, E, Norcliffe-Kaufmann, L, Palma, JA, Kaufmann, H, Shakkottai, VG, Perkins, M, Newell, KL, Gasser, T, Schulte, C, Landi, F, Salvi, E, Cusi, D, Masliah, E, Kim, RC, Caraway, CA, Monuki, ES, Brunetti, M, Dawson, TM, Rosenthal, LS, Albert, MS, Pletnikova, O, Troncoso, JC, Flanagan, ME, Mao, QW, Bigio, EH, Rodriguez-Rodriguez, E, Infante, J, Lage, C, Gonzalez-Aramburu, I, Sanchez-Juan, P, Ghetti, B, Keith, J, Black, SE, Masellis, M, Rogaeva, E, Duyckaerts, C, Brice, A, Lesage, S, Xiromerisiou, G, Barrett, MJ, Tilley, BS, Gentleman, S, Logroscino, G, Serrano, GE, Beach, TG, McKeith, IG, Thomas, AJ, Attems, J, Morris, CM, Palmer, L, Love, S, Troakes, C, Al-Sarraj, S, Hodges, AK, Aarsland, D, Klein, G, Kaiser, SM, Woltjer, R, Pastor, P, Bekris, LM, Leverenz, JB, Besser, LM, Kuzma, A, Renton, AE, Goate, A, Bennett, DA, Scherzer, CR, Morris, HR, Ferrari, R, Albani, D, Pickering-Brown, S, Faber, K, Kukull, WA, Morenas-Rodriguez, E, Lleo, A, Fortea, J, Alcolea, D, Clarimon, J, Nalls, MA, Ferrucci, L, Resnick, SM, Tanaka, T, Foroud, TM, Graff-Radford, NR, Wszolek, ZK, Ferman, T, Boeve, BF, Hardy, JA, Topol, EJ, Torkamani, A, Singleton, AB, Ryten, M, Dickson, DW, Chio, A, Ross, OA, Gibbs, JR, Dalgard, CL, Traynor, BJ, Scholz, SW, Amer Genome Ctr

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Publicada: 1 mar 2021 Ahead of Print: 1 feb 2021

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Filiaciones:
Chia, R:
 NIA, Neuromuscular Dis Res Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Sabir, MS:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Bandres-Ciga, S:
 NIA, Mol Genet Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Saez-Atienzar, S:
 NIA, Neuromuscular Dis Res Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Reynolds, RH:
 UCL, Dept Neurodegenerat Dis, UCL Queen Sq Inst Neurol, London, England

 UCL, NIHR Great Ormond St Hosp, Biomed Res Ctr, London, England

 UCL, Great Ormond St Inst Child Hlth Genet & Genom Med, London, England

Gustavsson, E:
 UCL, NIHR Great Ormond St Hosp, Biomed Res Ctr, London, England

 UCL, Great Ormond St Inst Child Hlth Genet & Genom Med, London, England

Walton, RL:
 Mayo Clin, Dept Neurosci, Jacksonville, FL USA

Ahmed, S:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Viollet, C:
 Uniformed Serv Univ Hlth Sci, Collaborat Hlth Initiat Res Program, Bethesda, MD 20814 USA

 Henry M Jackson Fdn Adv Mil Med Inc, Bethesda, MD USA

Ding, JH:
 NIA, Computat Biol Grp, Lab Neurogenet, Bethesda, MD 20892 USA

Makarious, MB:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Diez-Fairen, M:
 Univ Hosp Mutua Terrassa, Dept Neurol, Memory & Movement Disorders Units, Barcelona, Spain

Portley, MK:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Shah, Z:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Abramzon, Y:
 NIA, Neuromuscular Dis Res Sect, Lab Neurogenet, Bethesda, MD 20892 USA

 UCL, Reta Lila Weston Inst, UCL Queen Sq Inst Neurol, London, England

Hernandez, DG:
 NIA, Mol Genet Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Blauwendraat, C:
 NIA, Mol Genet Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Stone, DJ:
 Cerevel Therapeut, Boston, MA USA

Eicher, J:
 Merck & Co Inc, Genet & Pharmacogen, West Point, PA USA

Parkkinen, L:
 Univ Oxford, Oxford Parkinsons Dis Ctr, Nuffield Dept Clin Neurosci, Oxford, England

Ansorge, O:
 Univ Oxford, Oxford Parkinsons Dis Ctr, Nuffield Dept Clin Neurosci, Oxford, England

Clark, L:
 Columbia Univ, Taub Inst Alzheimer Dis & Aging Brain, New York, NY USA

 Columbia Univ, Dept Pathol & Cell Biol, New York, NY USA

Honig, LS:
 Columbia Univ, GH Sergievsky Ctr, Taub Inst Alzheimer Dis & Aging Brain, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

Marder, K:
 Columbia Univ, GH Sergievsky Ctr, Taub Inst Alzheimer Dis & Aging Brain, New York, NY USA

 Columbia Univ, Dept Neurol, New York, NY USA

Lemstra, A:
 Neurosci Campus Amsterdam, Dept Neurol, Amsterdam, Netherlands

 Neurosci Campus Amsterdam, Alzheimer Ctr, Amsterdam, Netherlands

St George-Hyslop, P:
 Univ Cambridge, Cambridge Inst Med Res, Dept Clin Neurosci, Cambridge, England

 Univ Toronto, Dept Med, Toronto, ON, Canada

Londos, E:
 Lund Univ, Inst Clin Sci Malmo, Clin Memory Res Unit, Lund, Sweden

Morgan, K:
 Univ Nottingham, Queens Med Ctr, Sch Life Sci, Nottingham, England

Lashley, T:
 UCL, Dept Neurodegenerat Dis, UCL Queen Sq Inst Neurol, London, England

 UCL, UCL Queen Sq Inst Neurol, Dept Clin & Movement Neurosci, Queen Sq Brain Bank Neurol Disorders, London, England

Warner, TT:
 UCL, Reta Lila Weston Inst, UCL Queen Sq Inst Neurol, London, England

 UCL, UCL Queen Sq Inst Neurol, Dept Clin & Movement Neurosci, Queen Sq Brain Bank Neurol Disorders, London, England

Jaunmuktane, Z:
 UCL, UCL Queen Sq Inst Neurol, Dept Clin & Movement Neurosci, Queen Sq Brain Bank Neurol Disorders, London, England

Galasko, D:
 Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA

 Vet Affairs San Diego Healthcare Syst, La Jolla, CA USA

Santana, I:
 Univ Coimbra Hosp, Neurol Serv, Coimbra, Portugal

 Ctr Hosp & Univ Coimbra, Coimbra, Portugal

 Univ Coimbra, Fac Med, Coimbra, Portugal

 Univ Coimbra, Ctr Innovat Biomed & Biotechnol, Coimbra, Portugal

Tienari, PJ:
 Univ Helsinki, Res Programs Unit, Translat Immunol, Helsinki, Finland

 Helsinki Univ Hosp, Dept Neurol, Helsinki, Finland

Myllykangas, L:
 Univ Helsinki, Dept Pathol, Med, Helsinki, Finland

 Helsinki Univ Hosp, HUS Diagnost Ctr, Helsinki, Finland

Oinas, M:
 UiT Arctic Univ Norway, Fac Hlth, Dept Clin Med, Tromso, Norway

Cairns, NJ:
 Washington Univ, Sch Med, Dept Neurol, Knight Alzheimers Dis Res Ctr, St Louis, MO 63110 USA

Morris, JC:
 Washington Univ, Sch Med, Dept Neurol, Knight Alzheimers Dis Res Ctr, St Louis, MO 63110 USA

Halliday, GM:
 Neurosci Res Australia, Sydney, NSW, Australia

 Univ New South Wales, Fac Med, Sch Med Sci, Sydney, NSW, Australia

 Univ Sydney, Brain & Mind Ctr, Sydney Med Sch, Sydney, NSW, Australia

Van Deerlin, VM:
 Univ Penn, Dept Pathol & Lab Med, Ctr Neurodegenerat Dis Res, Perelman Sch Med, Philadelphia, PA USA

Trojanowski, JQ:
 Univ Penn, Dept Pathol & Lab Med, Ctr Neurodegenerat Dis Res, Perelman Sch Med, Philadelphia, PA USA

Grassano, M:
 NIA, Neuromuscular Dis Res Sect, Lab Neurogenet, Bethesda, MD 20892 USA

 Univ Turin, Rita Levi Montalcini Dept Neurosci, Turin, Italy

Calvo, A:
 Univ Turin, Rita Levi Montalcini Dept Neurosci, Turin, Italy

 Azienda Osped Univ Citt Salute & Sci, Turin, Italy

Mora, G:
 IRCCS, Ist Clin Sci Maugeri, Milan, Italy

Canosa, A:
 Univ Turin, Rita Levi Montalcini Dept Neurosci, Turin, Italy

 Azienda Osped Univ Citt Salute & Sci, Turin, Italy

Floris, G:
 Univ Hosp Cagliari, Dept Neurol, Cagliari, Italy

Bohannan, RC:
 Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA USA

Brett, F:
 Beaumont Hosp, Neuropathol Dept, Dublin Brain Bank, Dublin, Ireland

Gan-Or, Z:
 McGill Univ, Montreal Neurol Inst & Hosp, Dept Neurol & Neurosurg, Montreal, PQ, Canada

Geiger, JT:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Moore, A:
 NIA, Computat Biol Grp, Lab Neurogenet, Bethesda, MD 20892 USA

May, P:
 Univ Luxembourg, Luxembourg Ctr Syst Biomed, Esch Sur Alzette, Luxembourg

Kruger, R:
 Univ Luxembourg, Luxembourg Ctr Syst Biomed, Esch Sur Alzette, Luxembourg

 Luxembourg Inst Hlth, Transversal Translat Med, Strassen, Luxembourg

 Ctr Hosp Luxembourg, Parkinson Res Clin, Luxembourg, Luxembourg

Goldstein, DS:
 NINDS, Clin Neurocardiol Sect, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

Lopez, G:
 NHGRI, Med Genet Branch, Bethesda, MD 20892 USA

Tayebi, N:
 NHGRI, Med Genet Branch, Bethesda, MD 20892 USA

Sidransky, E:
 NHGRI, Med Genet Branch, Bethesda, MD 20892 USA

Norcliffe-Kaufmann, L:
 NYU, Sch Med, Dept Med, New York, NY USA

Palma, JA:
 NYU, Sch Med, Dept Med, New York, NY USA

Kaufmann, H:
 NYU, Sch Med, Dept Med, New York, NY USA

Shakkottai, VG:
 Univ Michigan, Dept Neurol, Sch Med, Ann Arbor, MI USA

Perkins, M:
 Univ Michigan, Sch Med, Michigan Brain Bank, Ann Arbor, MI USA

Newell, KL:
 Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA

Gasser, T:
 Univ Tubingen, Dept Neurodegenerat Dis, Ctr Neurol, Tubingen, Germany

 Univ Tubingen, Hertie Inst Clin Brain Res, Tubingen, Germany

 German Ctr Neurodegenerat Dis, Tubingen, Germany

Schulte, C:
 Univ Tubingen, Dept Neurodegenerat Dis, Ctr Neurol, Tubingen, Germany

 Univ Tubingen, Hertie Inst Clin Brain Res, Tubingen, Germany

 German Ctr Neurodegenerat Dis, Tubingen, Germany

Landi, F:
 Univ Cattolica Sacro Cuore, Fdn Policlin Univ Agostino Gemelli, IRCCS, Rome, Italy

Salvi, E:
 Fdn IRCCS Ist Neurol Carlo Besta, Neuroalgol Unit, Milan, Italy

Cusi, D:
 Bio4Dreams Business Nursery For Life, Milan, Italy

Masliah, E:
 NIA, Mol Neuropathol Sect, Lab Neurogenet, Bethesda, MD 20892 USA

Kim, RC:
 Univ Calif Irvine, Sch Med, Dept Neuropathol, Irvine, CA 92717 USA

Caraway, CA:
 Univ Calif Irvine, Inst Memory Impairments & Neurol Disorders, Irvine, CA USA

Monuki, ES:
 Univ Calif Irvine, Sch Med, Dept Pathol & Lab Med, Irvine, CA 92717 USA

Brunetti, M:
 Univ Turin, Rita Levi Montalcini Dept Neurosci, Turin, Italy

Dawson, TM:
 Johns Hopkins Univ, Med Ctr, Dept Neurol, Baltimore, MD 21218 USA

 Johns Hopkins Univ, Med Ctr, Inst Cell Engn, Neuroregenerat & Stem Cell Programs, Baltimore, MD 21218 USA

 Johns Hopkins Univ, Dept Pharmacol & Mol Sci, Med Ctr, Baltimore, MD 21218 USA

 Johns Hopkins Univ, Solomon H Snyder Dept Neurosci, Med Ctr, Baltimore, MD 21218 USA

Rosenthal, LS:
 Johns Hopkins Univ, Med Ctr, Dept Neurol, Baltimore, MD 21218 USA

Albert, MS:
 Johns Hopkins Univ, Med Ctr, Dept Neurol, Baltimore, MD 21218 USA

Pletnikova, O:
 Johns Hopkins Univ, Dept Pathol Neuropathol, Med Ctr, Baltimore, MD 21218 USA

 Univ Buffalo, Jacobs Sch Med & Biomed Sci, Dept Pathol & Anat Sci, Buffalo, NY USA

Troncoso, JC:
 Johns Hopkins Univ, Dept Pathol Neuropathol, Med Ctr, Baltimore, MD 21218 USA

Flanagan, ME:
 Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA

 Northwestern Univ, Dept Pathol, Feinberg Sch Med, Chicago, IL 60611 USA

Mao, QW:
 Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA

 Northwestern Univ, Dept Pathol, Feinberg Sch Med, Chicago, IL 60611 USA

Bigio, EH:
 Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA

 Northwestern Univ, Dept Pathol, Feinberg Sch Med, Chicago, IL 60611 USA

Rodriguez-Rodriguez, E:
 Univ Hosp Marques de Valdecilla, Neurol Serv, IDIVAL UC CIBERNED, Santander, Spain

Infante, J:
 Univ Hosp Marques de Valdecilla, Neurol Serv, IDIVAL UC CIBERNED, Santander, Spain

Lage, C:
 Univ Hosp Marques de Valdecilla, Neurol Serv, IDIVAL UC CIBERNED, Santander, Spain

Gonzalez-Aramburu, I:
 Univ Hosp Marques de Valdecilla, Neurol Serv, IDIVAL UC CIBERNED, Santander, Spain

Sanchez-Juan, P:
 Univ Hosp Marques de Valdecilla, Neurol Serv, IDIVAL UC CIBERNED, Santander, Spain

Ghetti, B:
 Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA

Keith, J:
 Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Anat Pathol, Toronto, ON, Canada

Black, SE:
 Univ Toronto, Fac Med, Inst Med Sci, Toronto, ON, Canada

 Univ Toronto, Dept Med, Div Neurol, Toronto, ON, Canada

 Univ Toronto, Heart & Stroke Fdn Canadian Partnership Stroke Re, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada

 Univ Toronto, Sunnybrook Res Inst, Hurvitz Brain Sci Res Program, Toronto, ON, Canada

 Univ Toronto, Sunnybrook Res Inst, LC Campbell Cognit Neurol Res Unit, Toronto, ON, Canada

Masellis, M:
 Univ Toronto, Dept Med, Div Neurol, Toronto, ON, Canada

 Univ Toronto, Sunnybrook Res Inst, Hurvitz Brain Sci Res Program, Toronto, ON, Canada

 Univ Toronto, Sunnybrook Res Inst, LC Campbell Cognit Neurol Res Unit, Toronto, ON, Canada

 Univ Toronto, Sunnybrook Hlth Sci Ctr, Cognit & Movement Disorders Clin, Toronto, ON, Canada

Rogaeva, E:
 Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada

Duyckaerts, C:
 Sorbonne Univ, Dept Neuropathol Escourolle, Paris Brain Inst, Paris, France

 Sorbonne Univ, Inst Cerveau, Paris Brain Inst,DMU Neurosci 6, ICM,INSERM,CNRS,Hop Pitie Salpetriere,AP HP, Paris, France

Brice, A:
 Sorbonne Univ, Inst Cerveau, Paris Brain Inst,DMU Neurosci 6, ICM,INSERM,CNRS,Hop Pitie Salpetriere,AP HP, Paris, France

Lesage, S:
 Sorbonne Univ, Inst Cerveau, Paris Brain Inst,DMU Neurosci 6, ICM,INSERM,CNRS,Hop Pitie Salpetriere,AP HP, Paris, France

Xiromerisiou, G:
 Univ Thessalia, Univ Hosp Larissa, Dept Neurol, Larisa, Greece

Barrett, MJ:
 Virginia Commonwealth Univ, Dept Neurol, Richmond, VA USA

Tilley, BS:
 Imperial Coll London, Dept Brain Sci, Neuropathol Unit, London, England

Gentleman, S:
 Imperial Coll London, Dept Brain Sci, Neuropathol Unit, London, England

Logroscino, G:
 Univ Aldo Moro, Dept Basic Med Neurosci & Sense Organs, Bari, Italy

 Univ Bari, Dept Clin Res Neurol, Ctr Neurodegenerat Dis & Aging Brain, Pia Fdn Card G Panico Hosp Tricase Le, Bari, Italy

Serrano, GE:
 Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Sun City, AZ USA

Beach, TG:
 Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Sun City, AZ USA

McKeith, IG:
 Newcastle Univ, Newcastle Brain Tissue Resource, Bristol Med Sch, Biomed Res Bldg, Newcastle Upon Tyne, Tyne & Wear, England

Thomas, AJ:
 Newcastle Univ, Newcastle Brain Tissue Resource, Bristol Med Sch, Biomed Res Bldg, Newcastle Upon Tyne, Tyne & Wear, England

Attems, J:
 Newcastle Univ, Newcastle Brain Tissue Resource, Bristol Med Sch, Biomed Res Bldg, Newcastle Upon Tyne, Tyne & Wear, England

Morris, CM:
 Newcastle Univ, Newcastle Brain Tissue Resource, Bristol Med Sch, Biomed Res Bldg, Newcastle Upon Tyne, Tyne & Wear, England

Palmer, L:
 Univ Bristol, Bristol Med Sch, South West Dementia Brain Bank, Bristol, Avon, England

Love, S:
 Univ Bristol, Bristol Med Sch, Dementia Res Grp, Bristol, Avon, England

Troakes, C:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

Al-Sarraj, S:
 Kings Coll Hosp London, Inst Psychiat Psychol & Neurosci, Dept Clin Neuropathol, London, England

 Kings Coll Hosp London, Inst Psychiat Psychol & Neurosci, London Neurodegenerat Dis Brain Bank, London, England

 Kings Coll London, London, England

Hodges, AK:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

Aarsland, D:
 Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

 Stavanger Univ Hosp, Ctr Age Related Med, Stavanger, Norway

Klein, G:
 Rush Univ, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA

Kaiser, SM:
 Indiana Univ Sch Med, Dept Neuropathol, Indianapolis, IN 46202 USA

Woltjer, R:
 Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

Pastor, P:
 Univ Hosp Mutua Terrassa, Dept Neurol, Memory & Movement Disorders Units, Barcelona, Spain

Bekris, LM:
 Cleveland Clin, Genom Med Inst, Cleveland, OH USA

Leverenz, JB:
 Cleveland Clin, Neurol Inst, Cleveland Lou Ruvo Ctr Brain Hlth, Cleveland, OH USA

Besser, LM:
 Florida Atlantic Univ, Inst Human Hlth & Dis Intervent, Boca Raton, FL 33431 USA

Kuzma, A:
 Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA USA

Renton, AE:
 Icahn Sch Med Mt Sinai, Ronald M Loeb Ctr Alzheimers Dis, Nash Family Dept Neurosci, New York, NY 10029 USA

Goate, A:
 Icahn Sch Med Mt Sinai, Ronald M Loeb Ctr Alzheimers Dis, Nash Family Dept Neurosci, Dept Genet & Genom Sci, New York, NY 10029 USA

Bennett, DA:
 Rush Univ, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA

Scherzer, CR:
 Harvard Med Sch, Precis Neurol Program, Brigham & Womens Hosp, Boston, MA 02115 USA

Morris, HR:
 UCL, Dept Clin & Movement Neurosci, UCL Queen Sq Inst Neurol, London, England

Ferrari, R:
 UCL, Dept Neurodegenerat Dis, UCL Queen Sq Inst Neurol, London, England

Albani, D:
 Ist Ric Farmacol Mario Negri IRCCS, Dept Neurosci, Milan, Italy

Pickering-Brown, S:
 Univ Manchester, Fac Biol Med & Hlth, Div Neurosci & Expt Psychol, Manchester, Lancs, England

Faber, K:
 Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA

Kukull, WA:
 Univ Washington, Dept Epidemiol, Natl Alzheimers Coordinating Ctr, Seattle, WA 98195 USA

Morenas-Rodriguez, E:
 Ludwig Maximilians Univ Munchen, Biomed Ctr, Biochem, Munich, Germany

 Deutsch Zentrum Neurodegenerat Erkrankungen, Munich, Germany

 Univ Autonoma Barcelona, St Pau Biomed Res Inst, Hosp Santa Creu & St Pau, Barcelona, Spain

 Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain

Lleo, A:
 Univ Autonoma Barcelona, St Pau Biomed Res Inst, Hosp Santa Creu & St Pau, Barcelona, Spain

 Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain

Fortea, J:
 Univ Autonoma Barcelona, St Pau Biomed Res Inst, Hosp Santa Creu & St Pau, Barcelona, Spain

 Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain

Alcolea, D:
 Univ Autonoma Barcelona, St Pau Biomed Res Inst, Hosp Santa Creu & St Pau, Barcelona, Spain

 Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain

Clarimon, J:
 Univ Autonoma Barcelona, St Pau Biomed Res Inst, Hosp Santa Creu & St Pau, Barcelona, Spain

 Network Ctr Biomed Res Neurodegenerat Dis, Madrid, Spain

Nalls, MA:
 NIA, Lab Neurogenet, Bethesda, MD 20892 USA

 Data Tecn Int, Glen Echo, MD USA

 NIA, Ctr Alzheimers & Related Dementias, Bethesda, MD 20892 USA

Ferrucci, L:
 NIA, Longitudinal Studies Sect, Baltimore, MD 20892 USA

Resnick, SM:
 NIA, Lab Behav Neurosci, Baltimore, MD 20892 USA

Tanaka, T:
 NIA, Longitudinal Studies Sect, Baltimore, MD 20892 USA

Foroud, TM:
 Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA

Graff-Radford, NR:
 Mayo Clin, Dept Neurol, Jacksonville, FL USA

Wszolek, ZK:
 Mayo Clin, Dept Neurol, Jacksonville, FL USA

Ferman, T:
 Mayo Clin, Dept Psychiat & Psychol, Jacksonville, FL USA

Boeve, BF:
 Mayo Clin, Dept Neurol, Rochester, MN USA

Hardy, JA:
 UCL, Dept Neurodegenerat Dis, UCL Queen Sq Inst Neurol, London, England

 UCL, Reta Lila Weston Inst, UCL Queen Sq Inst Neurol, London, England

 UCL, UK Dementia Res Inst UCL, UCL Inst Neurol, London, England

 UCL, UCL Movement Disorders Ctr, London, England

 Hong Kong Univ Sci & Technol, Inst Adv Study, Hong Kong, Peoples R China

Topol, EJ:
 Scripps Res, Scripps Res Translat Inst, La Jolla, CA USA

Torkamani, A:
 Scripps Res, Scripps Res Translat Inst, La Jolla, CA USA

Singleton, AB:
 NIA, Mol Genet Sect, Lab Neurogenet, Bethesda, MD 20892 USA

 NIA, Ctr Alzheimers & Related Dementias, Bethesda, MD 20892 USA

Ryten, M:
 Univ Tubingen, Dept Neurodegenerat Dis, Ctr Neurol, Tubingen, Germany

 Univ Tubingen, Hertie Inst Clin Brain Res, Tubingen, Germany

 German Ctr Neurodegenerat Dis, Tubingen, Germany

Dickson, DW:
 Mayo Clin, Dept Neurosci, Jacksonville, FL USA

Chio, A:
 Univ Turin, Rita Levi Montalcini Dept Neurosci, Turin, Italy

 Azienda Osped Univ Citt Salute & Sci, Turin, Italy

 CNR, Inst Cognit Sci & Technol, Rome, Italy

Ross, OA:
 Mayo Clin, Dept Neurosci, Jacksonville, FL USA

 Mayo Clin, Dept Clin Genom, Jacksonville, FL USA

Gibbs, JR:
 NIA, Computat Biol Grp, Lab Neurogenet, Bethesda, MD 20892 USA

Dalgard, CL:
 Uniformed Serv Univ Hlth Sci, Dept Anat Physiol & Genet, Bethesda, MD 20814 USA

 Uniformed Serv Univ Hlth Sci, Amer Genome Ctr, Bethesda, MD 20814 USA

Traynor, BJ:
 NIA, Neuromuscular Dis Res Sect, Lab Neurogenet, Bethesda, MD 20892 USA

 UCL, Reta Lila Weston Inst, UCL Queen Sq Inst Neurol, London, England

 Johns Hopkins Univ, Med Ctr, Dept Neurol, Baltimore, MD 21218 USA

Scholz, SW:
 NINDS, Neurodegenerat Dis Res Unit, Lab Neurogenet, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

 Johns Hopkins Univ, Med Ctr, Dept Neurol, Baltimore, MD 21218 USA