Frequency of sensitization to the individual fragrances of fragrance mix I and II according to the factors included in the MOAHLFA index
Por:
Sanchez-Pujol, MJ, Docampo-Simon, A, Mercader, P, Gonzalez-Perez, R, Hervella-Garces, M, Sanz-Sanchez, T, Cordoba, S, Sanchez-Perez, J, Heras-Mendaza, F, Gimenez-Arnau, AM, Gatica-Ortega, ME, Pastor-Nieto, MA, Zaragoza, V, Carrascosa, JM, Garcia-Bravo, B, Ruiz-Gonzalez, I, Borrego, L, Sanchez-Pedreno, P, Frutos, JO, Armario-Hita, JC, Garcia-Gavin, J, Fernandez-Redondo, V, Serra, E, Silvestre, JF
Publicada:
1 jun 2021
Ahead of Print:
1 feb 2021
Resumen:
Background Fragrances constitute the second most frequent cause of allergic contact dermatitis in Spain.
Objectives To determine the rate of sensitization to the individual fragrances of fragrance mix (FM) I and FM II for each of the demographic and clinical factors included in the MOAHLFA (male, occupational dermatitis, atopic dermatitis, hand dermatitis, leg dermatitis, facial dermatitis, age) index.
Methods We conducted a 5-year retrospective study in 23 Spanish centres. We identified the patients who had undergone patch testing with a specific fragrance series after reacting positively to fragrance markers in a baseline series. We obtained the MOAHLFA index items in this population, then calculated for each demographic and clinical factor the frequencies of sensitization to the individual fragrances of FM I and FM II.
Results A specific fragrance series was patch tested in 1013 patients. The most frequent allergens in men, women, children, and retired people were Evernia prunastri (16%), geraniol (16.6%), isoeugenol (17.9%), and geraniol (22.4%), respectively. Citral (20.5%) and Lyral (14.5%) were the most common allergens in occupational eczemas and were also associated with a large proportion of hand and facial dermatitis.
Conclusions Frequency of sensitization to the individual fragrances of FM I and FM II varies with age, sex, affected body region, and history of occupational or atopic dermatitis.
Filiaciones:
Sanchez-Pujol, MJ:
Hosp Gen Univ Alicante ISABIAL, Dept Dermatol, Alicante, Spain
Docampo-Simon, A:
Hosp Gen Univ Alicante ISABIAL, Dept Dermatol, Alicante, Spain
Mercader, P:
Hosp Gen Univ Jose M Morales Meseguer, Dept Dermatol, Murcia, Spain
Gonzalez-Perez, R:
Hosp Univ Araba, Dept Dermatol, Vitoria, Spain
Hervella-Garces, M:
Complejo Hosp Navarra, Dept Dermatol, Pamplona, Spain
Sanz-Sanchez, T:
Hosp Univ Infanta Sofia, Dept Dermatol, Madrid, Spain
Cordoba, S:
Hosp Univ Fuenlabrada, Dept Dermatol, Fuenlabrada, Spain
Sanchez-Perez, J:
Hosp Univ Princesa, Dept Dermatol, Madrid, Spain
Heras-Mendaza, F:
Fdn Jimenez Diaz, Dept Dermatol, Madrid, Spain
Gimenez-Arnau, AM:
Univ Autonoma Barcelona, Hosp del Mar, Dept Dermatol, Barcelona, Spain
Gatica-Ortega, ME:
Complejo Hosp Toledo, Dept Dermatol, Toledo, Spain
Pastor-Nieto, MA:
Hosp Univ Guadalajara, Dept Dermatol, Guadalajara, Spain
Zaragoza, V:
Consorci Hosp Univ Valencia, Dept Dermatol, Valencia, Spain
Carrascosa, JM:
Hosp Badalona Germans Trias & Pujol, Dept Dermatol, Badalona, Spain
Garcia-Bravo, B:
Hosp Univ Virgen de la Macarena, Dept Dermatol, Seville, Spain
Ruiz-Gonzalez, I:
Hosp Univ Leon, Dept Dermatol, Leon, Spain
Borrego, L:
Univ Las Palmas Gran Canaria, Hosp Univ Insular Gran Canaria, Dept Dermatol, Las Palmas Gran Canaria, Spain
Sanchez-Pedreno, P:
Hosp Univ Virgen de la Arrixaca, Dept Dermatol, Murcia, Spain
Frutos, JO:
Hosp Univ 12 Octubre, Dept Dermatol, Madrid, Spain
Armario-Hita, JC:
Hosp Univ Puerto Real, Dept Dermatol, Cadiz, Spain
Garcia-Gavin, J:
Complejo Hosp Univ Vigo, Dept Dermatol, Vigo, Spain
Fernandez-Redondo, V:
Hosp Univ Santiago Compostela, Dept Dermatol, Santiago De Compostela, Spain
Serra, E:
Hosp Santa Creu & Sant Pau, Dept Dermatol, Barcelona, Spain
Silvestre, JF:
Hosp Gen Univ Alicante ISABIAL, Dept Dermatol, Alicante, Spain
Green Accepted
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