Nomenclature and clinical phenotypes of atopic dermatitis
Por:
Girolomoni, G, de Bruin-Weller, M, Aoki, V, Kabashima, K, Deleuran, M, Puig, L, Bansal, A, Rossi, AB
Publicada:
1 mar 2021
Resumen:
Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies. We support using the term 'atopic dermatitis' rather than eczema, because it describes the allergic background and inflammation ('itis') as drivers of the disease. Atopic dermatitis has many morphologic manifestations that vary by topographic area affected, age, or race and require consideration in differential diagnosis. Different phenotypes based on morphology and topographic location, ethnicity, and age are discussed. A better-defined phenotype identification for atopic dermatitis will facilitate earlier and correct diagnosis of this complex condition and inform selection of the most appropriate treatment choice in an era in which targeted therapies may generate more individualized patient care.
Filiaciones:
Girolomoni, G:
Univ Verona, Dept Med, Sect Dermatol & Venereol, Piazzale A Stefani 1, I-37126 Verona, Italy
de Bruin-Weller, M:
Univ Med Ctr, Natl Expertise Ctr Atop Dermatitis, Dept Dermatol & Allergol, Utrecht, Netherlands
Aoki, V:
Univ Sao Paulo, Dept Dermatol, Sch Med, Sao Paulo, Brazil
Kabashima, K:
Kyoto Univ, Dept Dermatol, Grad Sch Med, Kyoto, Japan
Deleuran, M:
Aarhus Univ Hosp, Dept Dermatol, Aarhus, Denmark
Puig, L:
Univ Autonoma Barcelona, Dept Dermatol, Hosp Santa Creu & St Pau, Barcelona, Spain
Bansal, A:
Regeneron Pharmaceut Inc, 777 Old Saw Mill River Rd, Tarrytown, NY 10591 USA
Rossi, AB:
Sanofi Genzyme, Cambridge, MA USA
Green Published, gold
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