The functioning assessment short test (FAST) applied to first-episode psychosis: Psychometric properties and severity thresholds
Por:
Amoretti, S, Mezquida, G, Rosa, AR, Bioque, M, Cuesta, MJ, Pina-Camacho, L, Garcia-Rizo, C, Barcones, F, Gonzalez-Pinto, A, Merchan-Naranjo, J, Corripio, I, Vieta, E, Baeza, I, Cortizo, R, Bonnin, CM, Torrent, C, Bernardo, M, PEPs Grp
Publicada:
1 jun 2021
Ahead of Print:
1 jun 2021
Resumen:
Functional impairment is a defining feature of psychotic disorders. The Functional Assessment Short Test (FAST) is one of the most widely used instruments to measure psychosocial functioning. However, cut-offs of impairment have been well-established for bipolar disorders, but not for other clinical populations. This study aims to analyse psychometric properties of the FAST and establish their corresponding cut-off values for the different severity gradations in a first-episode of non-affective psychosis (FEP) patients. Global Assessment Functioning (GAF) and FAST ratings from 212 non-affective FEP and 204 healthy controls were analyzed. The psychometric properties of FAST (internal consistency, concurrent validity, discriminant validity, factorial analyses and sensitivity to change) were analyzed. The severity gradations of the FAST were defined by the congruence between two grading methods: linear regression analysis (LRA) and percentiles. The FAST showed strong psychometric properties. LRA with the GAF scores yielded the following equation: GAF(score) = 80.83 - 0.639*FAST(score). The FAST ranges in non-affective FEP patients derived from LRA and percentiles, were as follows: 0-9 (No impairment); 10-19 (Minimal impairment); 20-34 (Mild impairment); 35-45 (Moderate impairment); 46-72 (Severe impairment). Patients with no functional impairment had a higher socioeconomic status, fewer depressive and negative symptoms, lower severity of illness and higher cognitive reserve level than the others groups. In conclusion, the FAST shows optimal psychometric properties which corroborate its applicability in FEP populations. It is a well-demonstrated valid instrument and the present cut-off scores could be implemented in clinical and research practice to assess properly the psychosocial functional outcome of non-affective FEP populations. (C) 2021 Elsevier B.V. and ECNP. All rights reserved.
Filiaciones:
Amoretti, S:
Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Mezquida, G:
Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Rosa, AR:
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Hosp Clin Porto Alegre, Lab Mol Psychiat, Porto Alegre, RS, Brazil
Univ Fed Rio Grande UFRGS, Dept Pharmacol, Porto Alegre, RS, Brazil
Univ Fed Rio Grande UFRGS, Postgrad Program Psychiat & Behav Sci, Porto Alegre, RS, Brazil
Bioque, M:
Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Cuesta, MJ:
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Complejo Hosp Navarra, Dept Psychiat, Pamplona, Spain
Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain
Pina-Camacho, L:
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Univ Complutense, Dept Child & Adolescent Psychiat, Inst Psychatry & Mental Hlth, Hosp Gen Univ Gregorio Maranon,IiSGM,Sch Med, Madrid, Spain
Garcia-Rizo, C:
Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Barcones, F:
Hosp Univ Miguel Servet, Dept Family Med, Zaragoza, Spain
Univ Zaragoza, Dept Med & Psychiat, Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza, Spain
Gonzalez-Pinto, A:
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Univ Basque Country, Bioaraba Res Inst, Dept Neuroci, Dept Psychiat,Araba Univ Hosp, Vitoria, Spain
Merchan-Naranjo, J:
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Corripio, I:
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
Univ Autonoma Barcelona UAB, Hosp Santa Creu & St Pau, Dept Psychiat, Inst Invest Biomed St Pau IIBSANT PAU, Barcelona, Spain
Vieta, E:
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Hosp Clin Barcelona, Neurosci Inst, Bipolar & Depress Disorders Unit, Barcelona, Spain
Baeza, I:
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Univ Barcelona, Hosp Clin Barcelona, Dept Child & Adolescent Psychiat & Psychol, Clin Inst Neurosci, 2017SGR881, Barcelona, Spain
Cortizo, R:
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Inst Neuropsiquiatria Adicciones INAD, Barcelona, Spain
Bonnin, CM:
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Torrent, C:
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
Bernardo, M:
Hosp Clin Barcelona, Neurosci Inst, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
Univ Barcelona, Inst Neurociencies, Dept Med, Barcelona, Spain
Biomed Res Networking Ctr Mental Hlth Network CIB, Barcelona, Spain
August Pi & Sunyer Biomed Res Inst, IDIBAPS, Barcelona, Spain
|