Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group


Por: Cai, K, Fuller, A, Zhang, YL, Hensey, O, Grossberg, D, Christensen, R, Shea, B, Singh, JA, McCarthy, GM, Rosenthal, AK, Filippou, G, Taylor, WJ, Diaz-Torne, C, Stamp, LK, Edwards, NL, Pascart, T, Becce, F, Nielsen, SM, Tugwell, P, Beaton, D, Abhishek, A, Tedeschi, SK, Dalbeth, N

Publicada: 1 ago 2021 Ahead of Print: 1 ago 2021
Resumen:
Introduction: Although calcium pyrophosphate deposition (CPPD) is common, there are no published outcome domains or validated measurement instruments for CPPD studies. In this paper, we describe the framework for development of the Outcome Measures in Rheumatology (OMERACT) CPPD Core Domain Sets. Methods: The OMERACT CPPD working group performed a scoping literature review and qualitative interview study. Generated outcomes were presented at the 2020 OMERACT CPPD virtual Special Interest Group (SIG) meeting with discussion focused on whether different core domain sets should be developed for different calcium pyrophosphate deposition (CPPD) clinical presentations and how the future CPPD Core Domain Set may overlap with already established osteoarthritis (OA) domains. These discussions informed development of a future work plan for development of the OMERACT CPPD Core Domain Sets. Findings: Domains identified from a scoping review of 112 studies and a qualitative interview study of 36 people (28 patients with CPPD, 7 health care professionals, one stakeholder) were mapped to core areas of OMERACT Filter 2.1. The majority of SIG participants agreed there was need to develop separate core domain sets for "short term" and "long term" studies of CPPD. Although CPPD + OA is common and core domain sets for OA have been established, participants agreed that existing OA core domain sets should not influence the development of OMERACT core domain sets for CPPD. Prioritization exercises (using Delphi methodology) will consider 40 potential domains for short term studies of CPPD and 47 potential domains for long term studies of CPPD. Conclusion: Separate OMERACT CPPD Core Domain Sets will be developed for "short term" studies for an individ-ual flare of acute CPP crystal arthritis and for "long term" studies that may include participants with any clinical presentation of CPPD (acute CPP crystal arthritis, chronic CPP crystal inflammatory arthritis, and/or CPPD + OA). (c) 2021 Elsevier Inc. All rights reserved.

Filiaciones:
Cai, K:
 Univ Auckland, Fac Med & Hlth Sci, Dept Med, Bone & Joint Res Grp, 85 Pk Rd, Auckland, New Zealand

Fuller, A:
 Univ Nottingham, Acad Rheumatol, Nottingham, England

 Nottingham NIHR BRC, Nottingham, England

Zhang, YL:
 Univ Auckland, Fac Med & Hlth Sci, Dept Med, Bone & Joint Res Grp, 85 Pk Rd, Auckland, New Zealand

Hensey, O:
 Cent Remedial Clin, Dublin, Ireland

Grossberg, D:
 Holy Cross Hosp, Silver Spring, MD USA

 Suburban Hosp, Bethesda, MD USA

Christensen, R:
 Bispebjerg & Frederiksberg Hosp, Parker Inst, Sect Biostat & Evidence Based Res, Copenhagen, Denmark

 Odense Univ Hosp, Univ Southern Denmark, Dept Clin Res, Res Unit Rheumatol, Odense, Denmark

Shea, B:
 Univ Ottawa, Ottawa Hosp Res Inst, Ottawa, ON, Canada

Singh, JA:
 VA Med Ctr, Med Serv, Birmingham, AL USA

 Univ Alabama Birmingham UAB, Sch Med, Dept Med, Birmingham, AL USA

 UAB Sch Publ Hlth, Dept Epidemiol, Birmingham, AL USA

McCarthy, GM:
 Univ Coll Dublin, Dublin, Ireland

Rosenthal, AK:
 Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA

Filippou, G:
 Univ Milan, ASST Fatebenefratelli L Sacco Univ Hosp, Rheumatol Unit, Milan, Italy

Taylor, WJ:
 Univ Otago, Dept Med, Wellington, New Zealand

Diaz-Torne, C:
 Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Dept Rheumatol, Barcelona, Spain

Stamp, LK:
 Univ Otago, Dept Med, Christchurch, New Zealand

Edwards, NL:
 Univ Florida, Coll Med, Dept Med, Gainesville, FL USA

Pascart, T:
 Lille Catholic Univ, Dept Rheumatol, Hosp St Philbert, Lille, France

Becce, F:
 Lausanne Univ Hosp, Dept Diagnost & Intervent Radiol, Lausanne, Switzerland

 Univ Lausanne, Lausanne, Switzerland

Nielsen, SM:
 Bispebjerg & Frederiksberg Hosp, Parker Inst, Sect Biostat & Evidence Based Res, Copenhagen, Denmark

 Odense Univ Hosp, Univ Southern Denmark, Dept Clin Res, Res Unit Rheumatol, Odense, Denmark

Tugwell, P:
 Univ Ottawa, Dept Med, Ottawa, ON, Canada

Beaton, D:
 Univ Toronto, Inst Work & Hlth, Toronto, ON, Canada

Abhishek, A:
 Univ Nottingham, Acad Rheumatol, Nottingham, England

 Nottingham NIHR BRC, Nottingham, England

Tedeschi, SK:
 Brigham & Womens Hosp, Div Rheumatol Inflammat & Immun, 75 Francis St, Boston, MA 02115 USA

Dalbeth, N:
 Univ Auckland, Fac Med & Hlth Sci, Dept Med, Bone & Joint Res Grp, 85 Pk Rd, Auckland, New Zealand
ISSN: 00490172
Editorial
W B SAUNDERS CO-ELSEVIER INC, 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA, Estados Unidos America
Tipo de documento: Article
Volumen: 51 Número: 4
Páginas: 946-950
WOS Id: 000687968500035
ID de PubMed: 34140183
imagen Green Accepted

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