Type and doses of oral anticoagulants and adherence to anticoagulant treatment in elderly patients with atrial fibrillation: the ESPARTA study
Por:
Mostaza, JM, Fernandez, CS, Guerra, LC, Surinach, JM, Tamarit, JJ, Diaz, JLD, Polo, IG, Santamaria, EF, Fernandez, MAF, Acebal, CD, Ramos, MFD, Rafols, C
Publicada:
1 mar 2018
Resumen:
Aim: To analyze the use of oral anticoagulants in elderly patients with atrial fibrillation in clinical practice. Patients & methods: Cross-sectional and multicenter study performed in atrial fibrillation patients >= 75 years treated with oral anticoagulants >= 3 months. Results: 837 patients (83.0 +/- 5.0 years; CHA(2)DS(2)-VASc 5.0 +/- 1.4; HAS-BLED 2.1 +/- 0.9; 70.8% vitamin K antagonists; 29.2% direct oral anticoagulants [DOACs]) were included. Poor adherence was observed in 27.9% of patients. Higher scores in the Pfeiffer's test and FRAIL scale were associated with poorer adherence. Among patients treated with DOACs, 62.3% received the lower doses. Having high CHADS(2) score and being older were associated with the use of low doses. Conclusion: 28% of patients had a poor adherence to anticoagulant treatment. 62% of patients were treated with the lower doses of DOACs.
Filiaciones:
Mostaza, JM:
Hosp Carlos III, Internal Med Serv, Madrid 28029, Spain
Fernandez, CS:
Hosp Univ La Princesa, Internal Med Serv, Madrid 28006, Spain
Guerra, LC:
Hosp Virgen Macarena, Internal Med Dept, Seville 41009, Spain
Surinach, JM:
Hosp Vall D Hebron, Serv Med Interna, Barcelona 08035, Spain
Tamarit, JJ:
Hosp Gen Valencia, Serv Med Interna, Valencia 46014, Spain
Diaz, JLD:
Complejo Univ Hosp A Coruna, Serv Med Interna, La Coruna 15006, Spain
Polo, IG:
Hosp Univ La Princesa, Internal Med Serv, Madrid 28006, Spain
Santamaria, EF:
Hosp Santa Creu & Sant Pau, Geriatr Unit, Barcelona 08041, Spain
Fernandez, MAF:
Hosp Univ Salamanca, Internal Med Serv, Salamanca 37120, Spain
Acebal, CD:
Hosp Mendaro, Internal Med Serv, Guipuzcoa 20850, Spain
Ramos, MFD:
Hosp Ntra Sra La Candelaria, Internal Med Serv, Tenerife 38010, Spain
Rafols, C:
Bayer Hispania SL, Dept Med, Barcelona 08037, Spain
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