Selective neck dissection in surgically treated head and neck squamous cell carcinoma patients with a clinically positive neck: Systematic review
Por:
Rodrigo, JP, Grilli, G, Shah, JP, Medina, JE, Robbins, KT, Takes, RP, Hamoir, M, Kowalski, LP, Suarez, C, Lopez, F, Quer, M, Boedeker, CC, de Bree, R, Coskun, H, Rinaldo, A, Silver, CE, Ferlito, A
Publicada:
1 abr 2018
Resumen:
Adequate treatment of lymph node metastases is essential for patients with head and neck squamous cell carcinoma (HNSCC). However, there is still no consensus on the optimal surgical treatment of the neck for patients with a clinically positive (cN+) neck. In this review, we analyzed current literature about the feasibility of selective neck dissection (SND) in surgically treated HNSCC patients with cN + neck using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. From the reviewed literature, it seems that SND is a valid option in patients with cN1 and selected cN2 neck disease (non-fixed nodes, absence of palpable metastases at level IV or V, or large volume ->3 cm multiple lymph nodes at multiple levels). Adjuvant (chemo) radiotherapy is fundamental to achieve good control rates in pN2 cases. The use of SND instead a comprehensive neck dissection (CND) could result in reduced morbidity and better functional results. We conclude that SND could replace a CND without compromising oncologic efficacy in cN1 and cN2 cases with the above-mentioned characteristics. (C) 2018 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
Filiaciones:
Rodrigo, JP:
Univ Oviedo, CIBERONC, IUOPA, Dept Otolaryngol,Hosp Univ Cent Asturias, Oviedo, Spain
Grilli, G:
Osped Riuniti Foggia, Div Otolaryngol, Foggia, Italy
Shah, JP:
Mem Sloan Kettering Canc Ctr, Head & Neck Serv, 1275 York Ave, New York, NY 10021 USA
Medina, JE:
Univ Oklahoma, Hlth Sci Ctr, Dept Otorhinolaryngol, Oklahoma City, OK USA
Robbins, KT:
Southern Illinois Univ, Sch Med, Div Otolaryngol Head & Neck Surg, Springfield, IL USA
Takes, RP:
Radboud Univ Nijmegen, Med Ctr, Dept Otolaryngol Head & Neck Surg, Nijmegen, Netherlands
Hamoir, M:
St Luc Univ Hosp & Canc Ctr, Dept Head & Neck Surg, Head & Neck Oncol Program, Brussels, Belgium
Kowalski, LP:
Hosp Canc AC Camargo, Ctr Tratamento & Pesquisa, Dept Otorhinolaryngol Head & Neck Surg, Sao Paulo, Brazil
Suarez, C:
ISCIII, Inst Invest Sanitaria Principado Asturias, Oviedo, Spain
ISCIII, CIBERONC, Oviedo, Spain
Univ Oviedo, Inst Univ Oncol Principado Asturias, Oviedo, Spain
Lopez, F:
Univ Oviedo, CIBERONC, IUOPA, Dept Otolaryngol,Hosp Univ Cent Asturias, Oviedo, Spain
Quer, M:
Hosp Santa Creu & Sant Pau, Dept Otolaryngol, Barcelona, Spain
Boedeker, CC:
Univ Freiburg, Dept Otorhinolaryngol Head & Neck Surg, Freiburg, Germany
de Bree, R:
Vrije Univ Amsterdam, Med Ctr, Dept Otolaryngol Head & Neck Surg, Amsterdam, Netherlands
Coskun, H:
Uludag Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Bursa, Turkey
Rinaldo, A:
Univ Udine, Sch Med, Udine, Italy
Silver, CE:
Univ Arizona, Coll Med, Dept Surg, Phoenix, AZ USA
Ferlito, A:
Int Head & Neck Sci Grp, Padua, Italy
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