A systematic review of how patients value COPD outcomes
Por:
Zhang, Y, Morgan, RL, Alonso-Coello, P, Wiercioch, W, Bala, MM, Jaeschke, RR, Styczen, K, Pardo-Hernandez, H, Selva, A, Begum, HA, Morgano, GP, Waligora, M, Agarwal, A, Ventresca, M, Strzebonska, K, Wasylewski, MT, Blanco-Silvente, L, Kerth, JL, Wang, MX, Zhang, YQ, Narsingam, S, Fei, YT, Guyatt, G, Schunemann, HJ
Publicada:
1 jul 2018
Resumen:
Our objective was to summarise systematically all research evidence related to how patients value outcomes in chronic obstructive pulmonary disease (COPD).
We conducted a systematic review (systematic review registration number CRD42015015206) by searching PubMed, Embase, PsycInfo and CINAHL, and included reports that assessed the relative importance of outcomes from COPD patients' perspective. Two authors independently determined the eligibility of studies, abstracted the eligible studies and assessed risk of bias. We narratively summarised eligible studies, meta-analysed utilities for individual outcomes and assessed the certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations approach.
We included 217 quantitative studies. Investigators most commonly used utility measurements of outcomes (n=136), discrete choice exercises (n=13), probability trade-off (n=4) and forced choice techniques (n=46). Patients rated adverse events as important but on average, less so than symptom relief. Exacerbation and hospitalisation due to exacerbation are the outcomes that COPD patients rate as most important. This systematic review provides a comprehensive registry of related studies.
Filiaciones:
Zhang, Y:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Morgan, RL:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Alonso-Coello, P:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
CIBERESP IIB St Pau, Iberoamer Cochrane Ctr, Barcelona, Spain
Wiercioch, W:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Bala, MM:
Jagiellonian Univ, Coll Med, Fac Med, Dept Hyg & Dietet, Krakow, Poland
Jaeschke, RR:
Jagiellonian Univ, Coll Med, Dept Psychiat, Sect Affect Disorders, Krakow, Poland
Styczen, K:
Jagiellonian Univ, Coll Med, Dept Psychiat, Sect Affect Disorders, Krakow, Poland
Pardo-Hernandez, H:
CIBERESP IIB St Pau, Iberoamer Cochrane Ctr, Barcelona, Spain
Selva, A:
Corp Sanitaria Parc Tauli, Clin Epidemiol & Canc Screening, Sabadell, Spain
Res Network Hlth Serv Chron Dis REDISSEC, Barcelona, Spain
Begum, HA:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Morgano, GP:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Waligora, M:
Jagiellonian Univ, Coll Med, Dept Philosophy & Bioeth, REMEDY,Res Eth Med Study Grp, Krakow, Poland
Agarwal, A:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Univ Toronto, Sch Med, Toronto, ON, Canada
Ventresca, M:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Strzebonska, K:
Jagiellonian Univ, Coll Med, Dept Philosophy & Bioeth, REMEDY,Res Eth Med Study Grp, Krakow, Poland
Wasylewski, MT:
Jagiellonian Univ, Coll Med, Dept Philosophy & Bioeth, REMEDY,Res Eth Med Study Grp, Krakow, Poland
Blanco-Silvente, L:
Univ Girona, Dept Med Sci, TransLab Res Grp, Girona, Spain
Kerth, JL:
Rhein Westfal TH Aachen, Fac Med, Dept Med Didact & Curricular Dev, Aachen, Germany
Wang, MX:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Zhang, YQ:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
Narsingam, S:
Dartmouth Hitchcock Med Ctr, Dartmouth Med Sch, Dept Med, Lebanon, NH 03766 USA
Fei, YT:
Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, Beijing, Peoples R China
Guyatt, G:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
McMaster Univ, Dept Med, Hamilton, ON, Canada
Schunemann, HJ:
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St W, Hamilton, ON L8S 4K1, Canada
McMaster Univ, Dept Med, Hamilton, ON, Canada
Bronze
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