Overview of mitral regurgitation in Europe: results from the European Registry of mitral regurgitation (EuMiClip)
Por:
Ruiz, JMM, Galderisi, M, Buonauro, A, Badano, L, Aruta, P, Swaans, MJ, Sanchis, L, Saraste, A, Monaghan, M, Theodoropoulos, KC, Papitsas, M, Liel-Cohen, N, Kobal, S, Bervar, M, Berlot, B, Filippatos, G, Ikonomidis, I, Katsanos, S, Tanner, FC, Cassani, D, Faletra, FF, Leo, LA, Martinez, A, Matabuena, J, Grande-Trillo, A, Alonso-Rodriguez, D, Mesa, D, Gonzalez-Alujas, T, Sitges, M, Carrasco-Chinchilla, F, Li, CH, Fernandez-Golfin, C, Zamorano, JL
Publicada:
1 may 2018
Resumen:
Aims To determine the prevalence of mitral regurgitation (MR) in a large cohort of consecutive patients undergoing clinically indicated echocardiography and to examine the distribution of primary and secondary MR
Methods and results All patients undergoing an echocardiographic study in 19 European centres within a 3-month period were prospectively included. MR assessment was performed as recommended by the European Association of Cardiovascular Imaging (EACVI). MR was classified according to mechanism as primary or secondary and aetiologies were reported. A total of 63 463 consecutive echocardiographic studies were reviewed. Any degree of MR was described in 15 501 patients. Concomitant valve disease of at least moderate grade was present in 28.5% of patients, being tricuspid regurgitation the most prevalent. In the subgroup of moderate and severe MR (n = 3309), 55% of patients had primary MR and 30% secondary MR. Both mechanisms were described in 14% of the studies. According to Carpentier's classification, 26.7% of MR were classified as I, 19.9% of MR as II, 22.4% of MR as IIIa, and 31.1% of MR as IIIb
Conclusion To date, this is the largest echocardiography-based study to analyse the prevalence and aetiology distribution of MR in Europe. The burden of secondary MR was higher than previously described, representing 30% of patients with significant MR. In our environment, degenerative disease is the most common aetiology of primary MR (60%), whereas ischaemic is the most common aetiology of secondary MR (51%). Up to 70% of patients with severe primary MR may have a Class I indication for surgery. However, the optimal therapeutic approach for secondary MR remains uncertain.
Filiaciones:
Ruiz, JMM:
Univ Alcala De Henares, Hosp Ramon & Cajal, Dept Cardiol, CIBERCV, Carretera Colmenar Km 9,100, Madrid 28034, Spain
Galderisi, M:
Federico II Univ Hosp, Dept Adv Biomed Sci, Lab Standard & Adv Echocardiog, Via S Pansini 5, I-80131 Naples, Italy
Buonauro, A:
Federico II Univ Hosp, Dept Adv Biomed Sci, Lab Standard & Adv Echocardiog, Via S Pansini 5, I-80131 Naples, Italy
Badano, L:
Padova Univ Hosp, Dept Cardiac Vasc & Thorac Sci, Via Giustiniani 2, I-35128 Padua, Italy
Aruta, P:
Padova Univ Hosp, Dept Cardiac Vasc & Thorac Sci, Via Giustiniani 2, I-35128 Padua, Italy
Swaans, MJ:
St Antonius Hosp, Dept Cardiol, Koekoekslaan 1, NL-3435 Nieuwegein, Netherlands
Sanchis, L:
St Antonius Hosp, Dept Cardiol, Koekoekslaan 1, NL-3435 Nieuwegein, Netherlands
Saraste, A:
Turku Univ Hosp, Dept Med, Kiinamyllynkatu 4-8, Turku 20521, Finland
Monaghan, M:
Kings Coll Hosp London, Dept Cardiol, Denmark Hill, London SE5 9RS, England
Theodoropoulos, KC:
Kings Coll Hosp London, Dept Cardiol, Denmark Hill, London SE5 9RS, England
Papitsas, M:
Kings Coll Hosp London, Dept Cardiol, Denmark Hill, London SE5 9RS, England
Liel-Cohen, N:
Soroka Med Ctr, Div Cardiol, Yitzhack I Rager Blvd 151, IL-84101 Beer Sheva, Israel
Ben Gurion Univ Negev, Yitzhack I Rager Blvd 151, IL-84101 Beer Sheva, Israel
Kobal, S:
Soroka Med Ctr, Div Cardiol, Yitzhack I Rager Blvd 151, IL-84101 Beer Sheva, Israel
Ben Gurion Univ Negev, Yitzhack I Rager Blvd 151, IL-84101 Beer Sheva, Israel
Bervar, M:
Univ Med Ctr Ljubljana, Dept Cardiol, Zaloska Cesta 7, Ljubljana 1000, Slovenia
Berlot, B:
Univ Med Ctr Ljubljana, Dept Cardiol, Zaloska Cesta 7, Ljubljana 1000, Slovenia
Filippatos, G:
Attikon Hosp, Dept Cardiol, Rimini 1, Chaidari 12462, Greece
Ikonomidis, I:
Attikon Hosp, Dept Cardiol, Rimini 1, Chaidari 12462, Greece
Katsanos, S:
Attikon Hosp, Dept Cardiol, Rimini 1, Chaidari 12462, Greece
Tanner, FC:
Univ Hosp Zurich, Dept Cardiol, Ramistr 100, CH-8091 Zurich, Switzerland
Cassani, D:
Univ Hosp Zurich, Dept Cardiol, Ramistr 100, CH-8091 Zurich, Switzerland
Faletra, FF:
Cardioctr Ticino, Dept Cardiol, Via Tesserete 48, CH-6900 Lugano, Switzerland
Leo, LA:
Cardioctr Ticino, Dept Cardiol, Via Tesserete 48, CH-6900 Lugano, Switzerland
Martinez, A:
Univ Hosp Santiago de Compostela, Dept Cardiol, Rua Choupana, Santiago De Compostela 15706, A Coruna, Spain
Matabuena, J:
Univ Hosp Virgen del Rocio, Dept Cardiol, Ave Manuel Siurot, Seville 41013, Spain
Grande-Trillo, A:
Univ Hosp Virgen del Rocio, Dept Cardiol, Ave Manuel Siurot, Seville 41013, Spain
Alonso-Rodriguez, D:
Hosp Leon, Dept Cardiol, Leon 24071, Spain
Mesa, D:
Univ Hosp Reina Sofia, Dept Cardiol, Ave Menendez Pidal, Cordoba 14004, Spain
Gonzalez-Alujas, T:
Univ Hosp Vall dHebron, Dept Cardiol, Passeig Vall dHebron 119-129, Barcelona 08035, Spain
Sitges, M:
Hosp Clin Barcelona, Thorax Inst, Cardiol Dept, Carrer Villarroel 170, E-08036 Barcelona, Spain
Carrasco-Chinchilla, F:
Univ Hosp Virgen Victoria, Dept Cardiol, Campus Teatinos, Malaga 29010, Spain
Li, CH:
Hosp Santa Creu & Sant Pau, Dept Med, Cardiol Div, Carrer St Quinti 89, Barcelona 08041, Spain
Fernandez-Golfin, C:
Univ Alcala De Henares, Hosp Ramon & Cajal, Dept Cardiol, CIBERCV, Carretera Colmenar Km 9,100, Madrid 28034, Spain
Zamorano, JL:
Univ Alcala De Henares, Hosp Ramon & Cajal, Dept Cardiol, CIBERCV, Carretera Colmenar Km 9,100, Madrid 28034, Spain
Hosp La Zarzuela, Univ Francisco de Vitoria, Dept Cardiol, Calle Pleyades 25, Madrid 28023, Spain
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