Influence of antrum size on gastric emptying and weight-loss outcomes after laparoscopic sleeve gastrectomy (preliminary analysis of a randomized trial)
Por:
Garay, M, Balague, C, Rodriguez-Otero, C, Gonzalo, B, Domenech, A, Pernas, JC, Gich, IJ, Minambres, I, Fernandez-Ananin, S, Targarona, EM
Publicada:
1 jun 2018
Resumen:
Laparoscopic sleeve gastrectomy (LSG) has increased in popularity in recent years as a definitive bariatric procedure. Despite its growing popularity worldwide, the surgical technique is not well standardized. There is a lack of evidence on the matter of the antrum size and its relation to gastric emptying and weight-loss outcomes. The aim of the study is to evaluate the influence of antrum size over gastric emptying and weight-loss outcomes.
Twenty-five patients were prospectively randomized according to the distance between the first firing and the pylorus: AR group (antrum resection-2 cm from the pylorus) and AP group (antrum preservation-5 cm from the pylorus). Gastric emptying (%GE) was evaluated by a gastric emptying scintigraphy before surgery, 2 months and 1 year after LSG. Antrum volume was measured using a MultiSlice CT Scan performed 2 months and 1 year after surgery. The percent of excess weight loss (%EWL) was calculated after 1 year follow-up.
At 2 months after LSG the mean %GE was 69.7 +/- 18 in the AR group and 72.8 +/- 20 in the AP group (p = 0.69). At 1 year it was 66.5 +/- 21 and 74.2 +/- 16 in the AR and AP groups, respectively (p = 0.30). A significant accelerated gastric emptying was observed at 2 months (p = 0.025) and at 1 year (p = 0.013) in the AP group. Meanwhile in the AR group this increase was not significant (p = 0.12 at 2 months and p = 0.21 at 1 year). Differences regarding the %EWL between groups were no statistically significant (p = 0.74).
After LSG there is a global tendency to an accelerated gastric emptying, although only significant in the antrum preservation group; however, no differences were observed regarding the %EWL between groups after 1 year follow-up.
Filiaciones:
Garay, M:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
Balague, C:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
Rodriguez-Otero, C:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
Gonzalo, B:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
Domenech, A:
Univ Autonoma Barcelona, Dept Nucl Med, Hosp Santa Creu & St Pau, Barcelona, Spain
Pernas, JC:
Univ Autonoma Barcelona, Dept Radiol, Hosp Santa Creu & St Pau, Barcelona, Spain
Gich, IJ:
Univ Autonoma Barcelona, Dept Epidemiol, Hosp Santa Creu & St Pau, Barcelona, Spain
Minambres, I:
Univ Autonoma Barcelona, Dept Endocrinol, Hosp Santa Creu & St Pau, Barcelona, Spain
Fernandez-Ananin, S:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
Targarona, EM:
Univ Autonoma Barcelona, Dept Surg, Hosp Santa Creu & St Pau, Barcelona, Spain
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