Basal cell carcinoma treated with Mohs micrographic surgery in young Ibero-American patients
Por:
Aluma-Tenorio, MS, Avila-Alvarez, A, Jaimes, N, Caballero-Uribe, N, Gonzalez, A, Terzian, LR, Ocampo-Candiani, J, Zuluaga, MA, Garza-Rodriguez, V, Tamayo-Betancur, MC, Cuesta-Castro, DP, Garces, JR, Ruiz-Salas, V, Goldberg, L, Kimyai-Asadi, A
Publicada:
1 dic 2018
Resumen:
Background The incidence of basal cell carcinoma (BCC) in younger individuals has increased in recent decades. However, the characteristics of BCCs in this population, especially in Ibero-Latin American countries, have not been completely defined. Objective Materials and Methods To describe the demographic, clinical, and histopathological characteristics of BCCs in patients younger than 40 treated with Mohs Micrographic Surgery (MMS). A multicenter, retrospective study conducted between January 2009 and December 2014, in five Ibero-American countries, included biopsy-proven BCCs in patients younger than 40 that were treated with MMS. Demographic, clinical, histopathological, and surgical characteristics were described. Results Conclusions The study included 301 tumors in 241 patients, of whom 61% were female. The most common Fitzpatrick phototype was III. The most common histological subtypes were nodular (37.5%) and infiltrative (18.9%). Perineural invasion was encountered in 1.7%, and tumor clearance was achieved in 87.4% within two stages of MMS. This is the first Ibero-Latin American transnational study describing the characteristics of BCCs in young patients treated with MMS. Despite darker skin phototypes in this population, BCCs can occur in early ages and may present with aggressive features. Therefore, MMS may be considered an appropriate first-line treatment option in this population.
Filiaciones:
Aluma-Tenorio, MS:
Aurora, Ctr Especializado Canc Piel, Cra 46 7-12, Medellin, Colombia
Avila-Alvarez, A:
Univ Pontificia Bolivariana, Medellin, Colombia
Jaimes, N:
Univ Miami, Miller Sch Med, Dept Dermatol & Cutaneous Surg, Miami, FL 33136 USA
Caballero-Uribe, N:
Aurora, Ctr Especializado Canc Piel, Cra 46 7-12, Medellin, Colombia
Univ Fed ABC, Santo Andre, SP, Brazil
Gonzalez, A:
Inst Med Especializado Alexander Fleming, Buenos Aires, DF, Argentina
Univ Buenos Aires, Inst Oncol Angel H Roffo, Buenos Aires, DF, Argentina
Terzian, LR:
Univ Fed ABC, Santo Andre, SP, Brazil
Ocampo-Candiani, J:
Univ Autonoma Nuevo Leon, Fac Med, Serv Dermatol, Univ Hosp, Monterrey, Mexico
Zuluaga, MA:
Univ Autonoma Nuevo Leon, Fac Med, Serv Dermatol, Univ Hosp, Monterrey, Mexico
Garza-Rodriguez, V:
Univ Autonoma Nuevo Leon, Fac Med, Serv Dermatol, Univ Hosp, Monterrey, Mexico
Tamayo-Betancur, MC:
Aurora, Ctr Especializado Canc Piel, Cra 46 7-12, Medellin, Colombia
Cuesta-Castro, DP:
Univ Pontificia Bolivariana, Medellin, Colombia
Garces, JR:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Ctr Med Teknon, Barcelona, Catalunya, Spain
Ruiz-Salas, V:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Ctr Med Teknon, Barcelona, Catalunya, Spain
Goldberg, L:
DermSurg Associates, Houston, TX USA
Kimyai-Asadi, A:
DermSurg Associates, Houston, TX USA
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