Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A beta, tau, immunity and lipid processing
Por:
Kunkle, BW, Grenier-Boley, B, Sims, R, Bis, JC, Damotte, V, Naj, AC, Boland, A, Vronskaya, M, van der Lee, SJ, Amlie-Wolf, A, Bellenguez, C, Frizatti, A, Chouraki, V, Martin, ER, Sleegers, K, Badarinarayan, N, Jakobsdottir, J, Hamilton-Nelson, KL, Moreno-Grau, S, Olaso, R, Raybould, R, Chen, YN, Kuzma, AB, Hiltunen, M, Morgan, T, Ahmad, S, Vardarajan, BN, Epelbaum, J, Hoffmann, P, Boada, M, Beecham, GW, Garnier, JG, Harold, D, Fitzpatrick, AL, Valladares, O, Moutet, ML, Gerrish, A, Smith, AV, Qu, LM, Bacq, D, Denning, N, Jian, XQ, Zhao, Y, Del Zompo, M, Fox, NC, Choi, SH, Mateo, I, Hughes, JT, Adams, HH, Malamon, J, Sanchez-Garcia, F, Patel, Y, Brody, JA, Dombroski, BA, Naranjo, MCD, Daniilidou, M, Eiriksdottir, G, Mukherjee, S, Wallon, D, Uphill, J, Aspelund, T, Cantwell, LB, Garzia, F, Galimberti, D, Hofer, E, Butkiewicz, M, Fin, B, Scarpini, E, Sarnowski, C, Bush, WS, Meslage, S, Kornhuber, J, White, CC, Song, Y, Barber, RC, Engelborghs, S, Sordon, S, Voijnovic, D, Adams, PM, Vandenberghe, R, Mayhaus, M, Cupples, LA, Albert, MS, De Deyn, PP, Gu, W, Himali, JJ, Beekly, D, Squassina, A, Hartmann, AM, Orellana, A, Blacker, D, Rodriguez-Rodriguez, E, Lovestone, S, Garcia, ME, Doody, RS, Munoz-Fernadez, C, Sussams, R, Lin, HH, Fairchild, TJ, Benito, YA, Holmes, C, Karamujic-Comic, H, Frosch, MP, Thonberg, H, Maier, W, Roschupkin, G, Ghetti, B, Giedraitis, V, Kawalia, A, Li, S, Huebinger, RM, Kilander, L, Moebus, S, Hernandez, I, Kamboh, MI, Brundin, R, Turton, J, Yang, Q, Katz, MJ, Concari, L, Lord, J, Beiser, AS, Keene, CD, Helisalmi, S, Kloszewska, I, Kukull, WA, Koivisto, AM, Lynch, A, Tarraga, L, Larson, EB, Haapasalo, A, Lawlor, B, Mosley, TH, Lipton, RB, Solfrizzi, V, Gill, M, Longstreth, WT, Montine, TJ, Frisardi, V, Diez-Fairen, M, Rivadeneira, F, Petersen, RC, Deramecourt, V, Alvarez, I, Salani, F, Ciaramella, A, Boerwinkle, E, Reiman, EM, Fievet, N, Rotter, JI, Reisch, JS, Hanon, O, Cupidi, C, Uitterlinden, AGA, Royall, DR, Dufouil, C, Maletta, RG, de Rojas, I, Sano, M, Brice, A, Cecchetti, R, St George-Hyslop, P, Ritchie, K, Tsolaki, M, Tsuang, DW, Dubois, B, Craig, D, Wu, CK, Soininen, H, Avramidou, D, Albin, RL, Fratiglioni, L, Germanou, A, Apostolova, LG, Keller, L, Koutroumani, M, Arnold, SE, Panza, F, Gkatzima, O, Asthana, S, Hannequin, D, Whitehead, P, Atwood, CS, Caffarra, P, Hampel, H, Quintela, I, Carracedo, A, Lannfelt, L, Rubinsztein, DC, Barnes, LL, Pasquier, F, Frolich, L, Barral, S, McGuinness, B, Beach, TG, Johnston, JA, Becker, JT, Passmore, P, Bigio, EH, Schott, JM, Bird, TD, Warren, JD, Boeve, BF, Lupton, MK, Bowen, JD, Proitsi, P, Boxer, A, Powell, JF, Burke, JR, Kauwe, JSK, Burns, JM, Mancuso, M, Buxbaum, JD, Bonuccelli, U, Cairns, NJ, McQuillin, A, Cao, CH, Livingston, G, Carlson, CS, Bass, NJ, Carlsson, CM, Hardy, J, Carney, RM, Bras, J, Carrasquillo, MM, Guerreiro, R, Allen, M, Chui, HC, Fisher, E, Masullo, C, Crocco, EA, DeCarli, C, Bisceglio, G, Dick, M, Ma, L, Duara, R, Graff-Radford, NR, Evans, DA, Hodges, A, Faber, KM, Scherer, M, Fallon, KB, Riemenschneider, M, Fardo, DW, Heun, R, Farlow, MR, Kolsch, H, Ferris, S, Leber, M, Foroud, TM, Heuser, I, Galasko, DR, Giegling, I, Gearing, M, Hull, M, Geschwind, DH, Gilbert, JR, Morris, J, Green, RC, Mayo, K, Growdon, JH, Feulner, T, Hamilton, RL, Harrell, LE, Drichel, D, Honig, LS, Cushion, TD, Huentelman, MJ, Hollingworth, P, Hulette, CM, Hyman, BT, Marshall, R, Jarvik, GP, Meggy, A, Abner, E, Menzies, GE, Jin, LW, Leonenko, G, Real, LM, Jun, GR, Baldwin, CT, Grozeva, D, Karydas, A, Russo, G, Kaye, JA, Kim, R, Jessen, F, Kowall, NW, Vellas, B, Kramer, JH, Vardy, E, LaFerla, FM, Jockel, KH, Lah, JJ, Dichgans, M, Leverenz, JB, Mann, D, Levey, AI, Pickering-Brown, S, Lieberman, AP, Klopp, N, Lunetta, KL, Wichmann, HE, Lyketsos, CG, Morgan, K, Marson, DC, Brown, K, Martiniuk, F, Medway, C, Mash, DC, Nothen, MM, Masliah, E, Hooper, NM, McCormick, WC, Daniele, A, McCurry, SM, Bayer, A, McDavid, AN, Gallacher, J, McKee, AC, van den Bussche, H, Mesulam, M, Brayne, C, Miller, BL, Riedel-Heller, S, Miller, CA, Miller, JW, Al-Chalabi, A, Morris, JC, Shaw, CE, Myers, AJ, Wiltfang, J, O'Bryant, S, Olichney, JM, Alvarez, V, Parisi, JE, Singleton, AB, Paulson, HL, Collinge, J, Perry, WR, Mead, S, Peskind, E, Cribbs, DH, Rossor, M, Pierce, A, Ryan, NS, Poon, WW, Nacmias, B, Potter, H, Sorbi, S, Quinn, JF, Sacchinelli, E, Raj, A, Spalletta, G, Raskind, M, Caltagirone, C, Bossu, P, Orfei, MD, Reisberg, B, Clarke, R, Reitz, C, Smith, AD, Ringman, JM, Warden, D, Roberson, ED, Wilcock, G, Rogaeva, E, Bruni, AC, Rosen, HJ, Gallo, M, Rosenberg, RN, Ben-Shlomo, Y, Sager, MA, Mecocci, P, Saykin, AJ, Pastor, P, Cuccaro, ML, Vance, JM, Schneider, JA, Schneider, LS, Slifer, S, Seeley, WW, Smith, AG, Sonnen, JA, Spina, S, Stern, RA, Swerdlow, RH, Tang, M, Tanzi, RE, Trojanowski, JQ, Troncoso, JC, Van Deerlin, VM, Van Eldik, LJ, Vinters, HV, Vonsattel, JP, Weintraub, S, Welsh-Bohmer, KA, Wilhelmsen, KC, Williamson, J, Wingo, TS, Woltjer, RL, Wright, CB, Yu, CE, Yu, L, Saba, Y, Pilotto, A, Bullido, MJ, Peters, O, Crane, PK, Bennett, D, Bosco, P, Coto, E, Boccardi, V, De Jager, PL, Lleo, A, Warner, N, Lopez, OL, Ingelsson, M, Deloukas, P, Cruchaga, C, Graff, C, Gwilliam, R, Fornage, M, Goate, AM, Sanchez-Juan, P, Kehoe, PG, Amin, N, Ertekin-Taner, N, Berr, C, Debette, S, Love, S, Launer, LJ, Younkin, SG, Dartigues, JF, Corcoran, C, Ikram, MA, Dickson, DW, Nicolas, G, Campion, D, Tschanz, J, Schmidt, H, Hakonarson, H, Clarimon, J, Munger, R, Schmidt, R, Farrer, LA, Van Broeckhoven, C, O'Donovan, MC, DeStefano, AL, Jones, L, Haines, JL, Deleuze, JF, Owen, MJ, Gudnason, V, Mayeux, R, Escott-Price, V, Psaty, BM, Ramirez, A, Wang, LS, Ruiz, A, van Duijn, CM, Holmans, PA, Seshadri, S, Williams, J, Amouyel, P, Schellenberg, GD, Lambert, JC, Pericak-Vance, MA
Publicada:
1 mar 2019
Resumen:
Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association meta-analysis of clinically diagnosed LOAD (94,437 individuals). We confirm 20 previous LOAD risk loci and identify five new genome-wide loci (IQCK, ACE, ADAM10, ADAMTS1, and WWOX), two of which (ADAM10, ACE) were identified in a recent genome-wide association (GWAS)-by-familial-proxy of Alzheimer's or dementia. Fine-mapping of the human leukocyte antigen (HLA) region confirms the neurological and immune-mediated disease haplotype HLA-DR15 as a risk factor for LOAD. Pathway analysis implicates immunity, lipid metabolism, tau binding proteins, and amyloid precursor protein (APP) metabolism, showing that genetic variants affecting APP and A beta processing are associated not only with early-onset autosomal dominant Alzheimer's disease but also with LOAD. Analyses of risk genes and pathways show enrichment for rare variants (P = 1.32 x 10(-7)), indicating that additional rare variants remain to be identified. We also identify important genetic correlations between LOAD and traits such as family history of dementia and education.
Filiaciones:
Kunkle, BW:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Grenier-Boley, B:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Sims, R:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Bis, JC:
Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA
Damotte, V:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Naj, AC:
Univ Penn, Perelman Sch Med, Ctr Clin Epidemiol & Biostat, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
Boland, A:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Vronskaya, M:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
van der Lee, SJ:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Amlie-Wolf, A:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Bellenguez, C:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Frizatti, A:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Chouraki, V:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Martin, ER:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Sleegers, K:
VIB, Ctr Mol Neurol, Neurodegenerat Brain Dis Grp, Antwerp, Belgium
Univ Antwerp, Inst Born Bunge, Lab Neurogenet, Antwerp, Belgium
Badarinarayan, N:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Jakobsdottir, J:
Iceland Heart Assoc, Kopavogur, Iceland
Hamilton-Nelson, KL:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Moreno-Grau, S:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Olaso, R:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Raybould, R:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Chen, YN:
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Kuzma, AB:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Hiltunen, M:
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
Morgan, T:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Ahmad, S:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Vardarajan, BN:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10027 USA
Columbia Univ, Dept Neurol, New York, NY USA
Epelbaum, J:
Univ Paris 05, INSERM, Ctr Psychiat & Neurosci, UMR 894, Paris, France
Hoffmann, P:
Univ Bonn, Inst Human Genet, Bonn, Germany
Univ Bonn, Life & Brain Ctr, Dept Genom, Bonn, Germany
Univ Basel, Univ Hosp, Div Med Genet, Basel, Switzerland
Univ Basel, Dept Biomed, Basel, Switzerland
Boada, M:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Beecham, GW:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Garnier, JG:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Harold, D:
Dublin City Univ, Sch Biotechnol, Dublin, Ireland
Fitzpatrick, AL:
Univ Washington, Dept Family Med, Seattle, WA 98195 USA
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
Valladares, O:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Moutet, ML:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Gerrish, A:
UCL Inst Neurol, Dept Neurodegenerat Dis, Dementia Res Ctr, London, England
Smith, AV:
Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA
Univ Iceland, Fac Med, Reykjavik, Iceland
Qu, LM:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Bacq, D:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Denning, N:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Jian, XQ:
Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA
Zhao, Y:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Del Zompo, M:
Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy
Fox, NC:
UCL Inst Neurol, Dept Neurodegenerat Dis, Dementia Res Ctr, London, England
UCL Inst Neurol, UK Dementia Res Inst UCL, Dept Neurodegenerat Dis, London, England
Choi, SH:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Mateo, I:
Univ Cantabria, Marques de Valdecilla Univ Hosp, Neurol Serv, Santander, Spain
Univ Cantabria, Marques de Valdecilla Univ Hosp, CIBERNED, Santander, Spain
IDIVAL, Santander, Spain
Hughes, JT:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
Adams, HH:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Malamon, J:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Sanchez-Garcia, F:
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
Patel, Y:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
Brody, JA:
Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA
Dombroski, BA:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Naranjo, MCD:
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
Daniilidou, M:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Eiriksdottir, G:
Iceland Heart Assoc, Kopavogur, Iceland
Mukherjee, S:
Univ Washington, Dept Med, Seattle, WA USA
Wallon, D:
Normandie Univ, UNIROUEN, Inserm U1245, Rouen, France
Rouen Univ Hosp, Dept Neurol, Dept Genet, Rouen, France
CNR MAJ, Normandy Ctr Genom & Personalized Med, Rouen, France
Uphill, J:
Inst Prion Dis, MRC Prion Unit UCL, Dept Neurodegenerat Dis, London, England
Aspelund, T:
Iceland Heart Assoc, Kopavogur, Iceland
Univ Iceland, Ctr Publ Hlth, Reykjavik, Iceland
Cantwell, LB:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Garzia, F:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Galimberti, D:
Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Neurodegenerat Dis Unit, Milan, Italy
Univ Milan, Ctr Dino Ferrari, Milan, Italy
Hofer, E:
Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria
Med Univ Graz, Inst Med Informat Stat & Documentat, Graz, Austria
Butkiewicz, M:
Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol, Cleveland, OH 44106 USA
Fin, B:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Scarpini, E:
Fdn IRCCS Ca Granda, Osped Maggiore Policlin, Neurodegenerat Dis Unit, Milan, Italy
Univ Milan, Ctr Dino Ferrari, Milan, Italy
Sarnowski, C:
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Bush, WS:
Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol, Cleveland, OH 44106 USA
Meslage, S:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Kornhuber, J:
Univ Erlangen Nurnberg, Dept Psychiat & Psychotherapy, Erlangen, Germany
White, CC:
Brd Inst, Program Med & Populat Genet, Cambridge, MA USA
Song, Y:
Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol, Cleveland, OH 44106 USA
Barber, RC:
Univ North Texas, Hlth Sci Ctr, Dept Pharmacol & Neurosci, Ft Worth, TX USA
Engelborghs, S:
Univ Antwerp, Inst Born Bunge, Lab Neurochem & Behav, Antwerp, Belgium
Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium
Hosp Network Antwerp, Memory Clin, Antwerp, Belgium
Sordon, S:
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
Voijnovic, D:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Adams, PM:
Univ Texas Southwestern Med Ctr Dallas, Dept Psychiat, Dallas, TX 75390 USA
Vandenberghe, R:
Univ Hosp, Dept Neurol, Lab Cognit Neurol, Leuven, Belgium
Univ Leuven, Leuven, Belgium
Mayhaus, M:
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
Cupples, LA:
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Albert, MS:
Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21218 USA
De Deyn, PP:
Univ Antwerp, Inst Born Bunge, Lab Neurochem & Behav, Antwerp, Belgium
Hosp Network Antwerp, Dept Neurol, Antwerp, Belgium
Hosp Network Antwerp, Memory Clin, Antwerp, Belgium
Gu, W:
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
Himali, JJ:
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Beekly, D:
Univ Washington, Natl Alzheimers Coordinating Ctr, Seattle, WA 98195 USA
Squassina, A:
Univ Cagliari, Dept Biomed Sci, Sect Neurosci & Clin Pharmacol, Cagliari, Italy
Hartmann, AM:
Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany
Orellana, A:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Blacker, D:
Harvard Univ, Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
Harvard Med Sch, Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02115 USA
Rodriguez-Rodriguez, E:
Univ Cantabria, Marques de Valdecilla Univ Hosp, Neurol Serv, Santander, Spain
Univ Cantabria, Marques de Valdecilla Univ Hosp, CIBERNED, Santander, Spain
IDIVAL, Santander, Spain
Lovestone, S:
Univ Oxford, Dept Psychiat, Oxford, England
Garcia, ME:
NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA
Doody, RS:
Baylor Coll Med, Alzheimers Dis & Memory Disorders Ctr, Houston, TX 77030 USA
Munoz-Fernadez, C:
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
Sussams, R:
Univ Southampton, Sch Med, Div Clin Neurosci, Southampton, Hants, England
Lin, HH:
Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02118 USA
Fairchild, TJ:
Univ North Texas, Hlth Sci Ctr, Off Strategy & Measurement, Ft Worth, TX USA
Benito, YA:
Hosp Univ Doctor Negrin, Dept Immunol, Las Palmas Gran Canaria, Spain
Holmes, C:
Univ Southampton, Sch Med, Div Clin Neurosci, Southampton, Hants, England
Karamujic-Comic, H:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Frosch, MP:
Massachusetts Gen Hosp, CS Kub Lab Neuropathol, Charlestown, MA USA
Thonberg, H:
Karolinska Univ Hosp Solna, Unit Hereditary Dementias, Theme Aging, Stockholm, Sweden
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Alzheimer Res Ctr, Div Neurogeriatr, Solna, Sweden
Maier, W:
German Ctr Neurodegenerat Dis, Bonn, Germany
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
Roschupkin, G:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Ghetti, B:
Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA
Giedraitis, V:
Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden
Kawalia, A:
Univ Hosp Bonn, Dept Neurodegenerat Dis & Geriatr Psychiat, Bonn, Germany
Li, S:
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Huebinger, RM:
Univ Texas Southwestern Med Ctr Dallas, Dept Surg, Dallas, TX 75390 USA
Kilander, L:
Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden
Moebus, S:
Univ Duisburg Essen, Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany
Hernandez, I:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Kamboh, MI:
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA USA
Univ Pittsburgh, Alzheimers Dis Res Ctr, Pittsburgh, PA USA
Brundin, R:
Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden
Turton, J:
Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England
Yang, Q:
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Katz, MJ:
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
Concari, L:
Univ Parma, DIMEC, Sect Neurosci, Parma, Italy
FERB Alzheimer Ctr, Gazzaniga, Bergamo, Italy
Lord, J:
Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England
Beiser, AS:
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Keene, CD:
Univ Washington, Dept Pathol, Seattle, WA 98195 USA
Helisalmi, S:
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
Kloszewska, I:
Med Univ Lodz, Elderly & Psychiat Disorders Dept, Lodz, Poland
Kukull, WA:
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
Koivisto, AM:
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
Lynch, A:
St James Hosp, Mercers Inst Res Aging, Dublin, Ireland
Trinity Coll Dublin, Dublin, Ireland
St James Hosp, Dublin, Ireland
Tarraga, L:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Larson, EB:
Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA
Haapasalo, A:
Univ Eastern Finland, AI Virtanen Inst Mol Sci, Kuopio, Finland
Lawlor, B:
St James Hosp, Mercers Inst Res Aging, Dublin, Ireland
Trinity Coll Dublin, Dublin, Ireland
St James Hosp, Dublin, Ireland
Mosley, TH:
Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA
Univ Mississippi, Med Ctr, Dept Geriatr, Jackson, MS 39216 USA
Univ Mississippi, Med Ctr, Dept Gerontol, Jackson, MS 39216 USA
Univ Mississippi, Med Ctr, Dept Neurol, Jackson, MS 39216 USA
Lipton, RB:
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
Solfrizzi, V:
Univ Bari, Interdisciplinary Dept Med, Geriatr Med & Memory Unity, Bari, Italy
Gill, M:
St James Hosp, Mercers Inst Res Aging, Dublin, Ireland
Trinity Coll Dublin, Dublin, Ireland
St James Hosp, Dublin, Ireland
Longstreth, WT:
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
Univ Washington, Dept Neurol, Seattle, WA 98195 USA
Montine, TJ:
Univ Washington, Dept Pathol, Seattle, WA 98195 USA
Frisardi, V:
Univ Bari, Ctr Aging Brain, Dept Geriatr, Bari, Italy
Diez-Fairen, M:
Fundacio Recerca Biomed & Social Mutua Terrassa, Barcelona, Spain
Hosp Univ Mutua Terrassa, Dept Neurol, Memory Disorders Unit, Barcelona, Spain
Rivadeneira, F:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Erasmus Univ, Dept Internal Med, Med Ctr, Rotterdamt, Netherlands
Netherlands Consortium Hlth Aging & Natl Genom In, Leiden, Netherlands
Petersen, RC:
Mayo Clin, Dept Neurol, Rochester, MN USA
Deramecourt, V:
CHU Lille, Memory Ctr Lille, Ctr Memoire Ressources & Rech, Lille, France
Alvarez, I:
Fundacio Recerca Biomed & Social Mutua Terrassa, Barcelona, Spain
Hosp Univ Mutua Terrassa, Dept Neurol, Memory Disorders Unit, Barcelona, Spain
Salani, F:
IRCCS Santa Lucia Fdn, Expt Neuropsychobiol Lab, Dept Clin & Behav Neurol, Rome, Italy
Ciaramella, A:
IRCCS Santa Lucia Fdn, Expt Neuropsychobiol Lab, Dept Clin & Behav Neurol, Rome, Italy
Boerwinkle, E:
Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Sch Publ Hlth, Houston, TX 77030 USA
Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA
Reiman, EM:
Translat Genom Res Inst, Neurogen Div, Phoenix, AZ USA
Arizona Alzheimers Consortium, Phoenix, AZ USA
Banner Alzheimers Inst, Phoenix, AZ USA
Univ Arizona, Dept Psychiat, Phoenix, AZ USA
Fievet, N:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Rotter, JI:
Harbor UCLA Med Ctr, Los Angeles BioMed Res Inst, Dept Pediat, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA
Harbor UCLA Med Ctr, Los Angeles BioMed Res Inst, Dept Med, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA
Reisch, JS:
Univ Texas Southwestern Med Ctr Dallas, Dept Clin Sci, Dallas, TX 75390 USA
Hanon, O:
Univ Paris 05, Hop Broca, AP HP, Geriatr Dept,EA 4468, Paris, France
Cupidi, C:
ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy
Uitterlinden, AGA:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Erasmus Univ, Dept Internal Med, Med Ctr, Rotterdamt, Netherlands
Netherlands Consortium Hlth Aging & Natl Genom In, Leiden, Netherlands
Royall, DR:
UT Hlth Sci Ctr San Antonio, South Texas Vet Hlth Adm Geriatr Res Educ & Clin, Dept Psychiat, San Antonio, TX USA
UT Hlth Sci Ctr San Antonio, South Texas Vet Hlth Adm Geriatr Res Educ & Clin, Dept Med, San Antonio, TX USA
UT Hlth Sci Ctr San Antonio, South Texas Vet Hlth Adm Geriatr Res Educ & Clin, Dept Family & Community Med, San Antonio, TX USA
Dufouil, C:
Univ Bordeaux, Inserm 1219, Bordeaux, France
Bordeaux Univ Hosp, CHU Bordeaux, Dept Neurol, Bordeaux, France
Maletta, RG:
ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy
de Rojas, I:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Sano, M:
Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA
Brice, A:
UPMC Univ Paris 06, Inst Cerveau & Moelle Epiniere, UMRS 1127, Inserm U1127,CNRS UMR 7225,Sorbonne Univ, Paris, France
Hop La Pitie Salpetriere, AP HP, Dept Genet, Paris, France
Cecchetti, R:
Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy
St George-Hyslop, P:
Univ Cambridge, Cambridge Inst Med Res, Cambridge, England
Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada
Ritchie, K:
La Colombiere Hosp, Inserm Neuropsychiat U1061, Montpellier, France
Montpellier Univ, Montpellier, France
Univ Edinburgh, Dept Clin Brain Sci, Edinburgh, Midlothian, Scotland
Tsolaki, M:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Tsuang, DW:
GRECC, VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA
Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
Dubois, B:
Hop La Pitie Salpetriere, Dept Neurol, Inst Memoire & Malad Alzheimer, Paris, France
Hop La Pitie Salpetriere, Dept Neurol, Inst Cerveau & Moelle Epiniere, Paris, France
Inst Cerveau & Moelle Epiniere, Inst Neurosci Translat Paris, Paris, France
Inst Cerveau & Moelle Epiniere, UMR 5975, CNRS, Inserm, Paris, France
Univ Paris 06, Sorbonne Univ, Hop Pitie Salpetriere, AP HP, Paris, France
Craig, D:
Queens Univ Belfast, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Ageing Grp, Belfast, Antrim, North Ireland
Wu, CK:
Texas Tech Univ, Hlth Sci Ctr, Dept Neurol, Lubbock, TX 79409 USA
Texas Tech Univ, Hlth Sci Ctr, Dept Pharmacol, Lubbock, TX 79409 USA
Texas Tech Univ, Hlth Sci Ctr, Dept Neurosci, Lubbock, TX 79409 USA
Soininen, H:
Univ Eastern Finland, Inst Biomed, Kuopio, Finland
Kuopio Univ Hosp, Dept Neurol, Kuopio, Finland
Avramidou, D:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Albin, RL:
Univ Michigan, Dept Neurol, Ann Arbor, MI USA
VAAAHS, GRECC, Ann Arbor, MI USA
Michigan Alzheimer Dis Ctr, Ann Arbor, MI USA
Fratiglioni, L:
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden
Stockholm Univ, Stockholm, Sweden
Germanou, A:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Apostolova, LG:
Indiana Univ Sch Med, Indiana Alzheimers Dis Ctr, Indianapolis, IN 46202 USA
Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN 46204 USA
Indiana Univ, Dept Neurol, Indianapolis, IN 46204 USA
Indiana Univ, Dept Radiol & Imaging Sci, Indianapolis, IN 46204 USA
Keller, L:
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Aging Res Ctr, Stockholm, Sweden
Stockholm Univ, Stockholm, Sweden
Koutroumani, M:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Arnold, SE:
Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA
Panza, F:
Univ Bari, Ctr Aging Brain, Dept Geriatr, Bari, Italy
Gkatzima, O:
Aristotle Univ Thessaloniki, Med Sch, Dept Neurol, Thessaloniki, Greece
Asthana, S:
Univ Wisconsin, GRECC, Madison, WI USA
Univ Wisconsin, Dept Med, Madison, WI USA
Wisconsin Alzheimers Dis Res Ctr, Madison, WI USA
Hannequin, D:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
Whitehead, P:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Atwood, CS:
Indiana Univ, Dept Med & Mol Genet, Indianapolis, IN 46204 USA
Indiana Univ, Dept Neurol, Indianapolis, IN 46204 USA
Indiana Univ, Dept Radiol & Imaging Sci, Indianapolis, IN 46204 USA
Caffarra, P:
Univ Pittsburgh, Alzheimers Dis Res Ctr, Pittsburgh, PA USA
Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England
Hampel, H:
AXA Res Fund, Paris, France
Sorbonne Univ Chair, Paris, France
Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, GRC 21,APM, Paris, France
Inserm U 1127, Brain & Spine Inst, CNRS UMR 7225, Paris, France
Hop La Pitie Salpetriere, AP HP, Dept Neurol, Inst Memory & Alzheimers Dis, Paris, France
Quintela, I:
Univ Santiago de Compostela, Grp Med Xenom, Ctr Nacl Genotipado, Ctr Invest Biomed Red Enfermedades Raras, Santiago De Compostela, Spain
Carracedo, A:
Univ Santiago de Compostela, Grp Med Xenom, Ctr Nacl Genotipado, Ctr Invest Biomed Red Enfermedades Raras, Santiago De Compostela, Spain
Lannfelt, L:
Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden
Rubinsztein, DC:
Univ Cambridge, Cambridge Inst Med Res, Cambridge, England
Univ Cambridge, UK Dementia Res Inst, Cambridge, England
Barnes, LL:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Behav Sci, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Pasquier, F:
CHU Lille, Memory Ctr Lille, Ctr Memoire Ressources & Rech, Lille, France
Frolich, L:
Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Heidelberg, Germany
Barral, S:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10027 USA
Columbia Univ, Dept Neurol, New York, NY USA
McGuinness, B:
Queens Univ Belfast, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Ageing Grp, Belfast, Antrim, North Ireland
Beach, TG:
Banner Sun Hlth Res Inst, Civin Lab Neuropathol, Phoenix, AZ USA
Johnston, JA:
Queens Univ Belfast, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Ageing Grp, Belfast, Antrim, North Ireland
Becker, JT:
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Sch Med, Dept Psychol, Pittsburgh, PA USA
Passmore, P:
Queens Univ Belfast, Sch Med Dent & Biomed Sci, Ctr Publ Hlth, Ageing Grp, Belfast, Antrim, North Ireland
Bigio, EH:
Northwestern Univ, Feinberg Sch Med, Dept Pathol, Chicago, IL 60611 USA
Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA
Schott, JM:
UCL Inst Neurol, Dept Neurodegenerat Dis, Dementia Res Ctr, London, England
Bird, TD:
Univ Washington, Dept Neurol, Seattle, WA 98195 USA
GRECC, VA Puget Sound Hlth Care Syst GRECC, Seattle, WA USA
Warren, JD:
UCL Inst Neurol, Dept Neurodegenerat Dis, Dementia Res Ctr, London, England
Boeve, BF:
Mayo Clin, Dept Neurol, Rochester, MN USA
Lupton, MK:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
QIMR Berghofer Med Res Inst, Genet Epidemiol, Herston, Qld, Australia
Bowen, JD:
Swedish Med Ctr, Seattle, WA USA
Proitsi, P:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
Boxer, A:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
Powell, JF:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Basic & Clin Neurosci, London, England
Burke, JR:
Duke Univ, Dept Neurol, Durham, NC USA
Kauwe, JSK:
Brigham Young Univ, Dept Biol, Provo, UT USA
Burns, JM:
Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA
Mancuso, M:
Univ Pisa, Neurol Inst, Dept Expt & Clin Med, Pisa, Italy
Buxbaum, JD:
Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA
Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA
Icahn Sch Med Mt Sinai, Dept Neurosci, New York, NY 10029 USA
Bonuccelli, U:
Univ Pisa, Neurol Inst, Dept Expt & Clin Med, Pisa, Italy
Cairns, NJ:
Washington Univ, Dept Pathol & Immunol, St Louis, MO USA
McQuillin, A:
UCL, Div Psychiat, London, England
Cao, CH:
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
Livingston, G:
UCL, Div Psychiat, London, England
Carlson, CS:
Univ Wisconsin, Dept Med, Madison, WI USA
Wisconsin Alzheimers Dis Res Ctr, Madison, WI USA
Bass, NJ:
UCL, Div Psychiat, London, England
Carlsson, CM:
Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
Hardy, J:
UCL, Dept Mol Neurosci, Inst Neurol, London, England
Carney, RM:
Bruce Carter VA Med Ctr, Mental Hlth & Behav Sci Serv, Miami, FL USA
Bras, J:
UCL Inst Neurol, UK Dementia Res Inst UCL, Dept Neurodegenerat Dis, London, England
UCL Inst Neurol, Dept Neurodegenerat Dis, London, England
Carrasquillo, MM:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Guerreiro, R:
UCL Inst Neurol, UK Dementia Res Inst UCL, Dept Neurodegenerat Dis, London, England
UCL Inst Neurol, Dept Neurodegenerat Dis, London, England
Allen, M:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Chui, HC:
Univ Southern Calif, Dept Neurol, Los Angeles, CA USA
Fisher, E:
UCL Inst Neurol, Dept Neurodegenerat Dis, London, England
Masullo, C:
Univ Cattolica Sacro Cuore, Dept Neurol, Rome, Italy
Crocco, EA:
Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA
DeCarli, C:
Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
Bisceglio, G:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Dick, M:
Univ Calif Irvine, Inst Memory Impairments & Neurol Disorders, Irvine, CA USA
Ma, L:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Duara, R:
Mt Sinai Med Ctr, Wien Ctr Alzheimers Dis & Memory Disorders, Miami Beach, FL 33140 USA
Graff-Radford, NR:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Evans, DA:
Rush Univ, Med Ctr, Dept Internal Med, Rush Inst Hlth Aging, Chicago, IL 60612 USA
Hodges, A:
Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Old Age Psychiat, London, England
Faber, KM:
Indiana Univ Sch Med, Indiana Alzheimers Dis Ctr, Indianapolis, IN 46202 USA
Scherer, M:
Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany
Fallon, KB:
Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA
Riemenschneider, M:
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
Fardo, DW:
Univ Kentucky, Sanders Brown Ctr Aging, Dept Biostat, Lexington, KY 40536 USA
Heun, R:
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
Farlow, MR:
Indiana Univ, Dept Neurol, Indianapolis, IN 46204 USA
Kolsch, H:
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
Ferris, S:
NYU, Dept Psychiat, 550 1St Ave, New York, NY 10016 USA
Leber, M:
Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany
Foroud, TM:
Indiana Univ Sch Med, Indiana Alzheimers Dis Ctr, Indianapolis, IN 46202 USA
Heuser, I:
Charite, Dept Psychiat & Psychotherapy, Berlin, Germany
Galasko, DR:
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Giegling, I:
Martin Luther Univ Halle Wittenberg, Dept Psychiat, Halle, Germany
Gearing, M:
Emory Univ, Dept Pathol & Lab Med, Atlanta, GA 30322 USA
Emory Univ, Emory Alzheimers Dis Ctr, Atlanta, GA 30322 USA
Hull, M:
Univ Freiburg, Dept Psychiat, Freiburg, Germany
Geschwind, DH:
Univ Calif Los Angeles, Neurogenet Program, Los Angeles, CA USA
Gilbert, JR:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Morris, J:
Washington Univ, Dept Pathol & Immunol, St Louis, MO USA
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
Washington Univ, Sch Med, Hope Ctr Program Prot Aggregat & Neurodegenerat, St Louis, MO USA
Washington Univ, Dept Neurol, St Louis, MO USA
Green, RC:
Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA
Brigham & Womens Hosp, Partners Ctr Personalized Genet Med, 75 Francis St, Boston, MA 02115 USA
Harvard Med Sch, Boston, MA 02115 USA
Mayo, K:
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
Washington Univ, Dept Neurol, St Louis, MO USA
Washington Univ, Dept Genet, St Louis, MO 63110 USA
Growdon, JH:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02115 USA
Feulner, T:
Univ Hosp, Dept Psychiat & Psychotherapy, Saarland, Germany
Hamilton, RL:
Univ Pittsburgh, Dept Pathol Neuropathol, Pittsburgh, PA USA
Harrell, LE:
Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
Drichel, D:
Univ Cologne, Cologne Ctr Genom, Cologne, Germany
Honig, LS:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Cushion, TD:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Huentelman, MJ:
Translat Genom Res Inst, Neurogen Div, Phoenix, AZ USA
Hollingworth, P:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Hulette, CM:
Duke Univ, Dept Pathol, Durham, NC 27706 USA
Hyman, BT:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02115 USA
Marshall, R:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Jarvik, GP:
Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA
Univ Washington, Dept Med Med Genet, Seattle, WA 98195 USA
Meggy, A:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Abner, E:
Univ Kentucky, Dept Epidemiol, Coll Publ Hlth, Sanders Brown Ctr Aging, Lexington, KY USA
Menzies, GE:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Jin, LW:
Hosp Univ Valme, Unidad Clin Enfermedades Infecciosas & Microbiol, Seville, Spain
Leonenko, G:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Real, LM:
Hosp Univ Valme, Unidad Clin Enfermedades Infecciosas & Microbiol, Seville, Spain
Jun, GR:
Boston Univ, Sch Med, Dept Med Biomed Genet, Boston, MA 02118 USA
Baldwin, CT:
Boston Univ, Sch Med, Dept Med Biomed Genet, Boston, MA 02118 USA
Grozeva, D:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Karydas, A:
Swedish Med Ctr, Seattle, WA USA
Russo, G:
ETH Univ Zurich, Funct Genom Ctr Zurich, Zurich, Switzerland
Kaye, JA:
Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA
Portland VA Med Ctr, Dept Neurol, Portland, OR USA
Kim, R:
Univ Calif Irvine, Dept Pathol & Lab Med, Irvine, CA USA
Jessen, F:
German Ctr Neurodegenerat Dis, Bonn, Germany
Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany
Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany
Kowall, NW:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Pathol, Boston, MA 02118 USA
Vellas, B:
Univ Toulouse, Inserm U558, Toulouse, France
Kramer, JH:
Univ Calif San Francisco, Dept Neuropsychol, San Francisco, CA 94143 USA
Vardy, E:
Newcastle Univ, Inst Ageing & Hlth, Newcastle Upon Tyne, Tyne & Wear, England
LaFerla, FM:
Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA USA
Jockel, KH:
Univ Duisburg Essen, Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany
Lah, JJ:
Emory Univ, Dept Neurol, Atlanta, GA USA
Dichgans, M:
Klinikum Univ Munchen, Inst Stroke & Dementia Res, Munich, Germany
German Ctr Neurodegenerat Dis, Munich, Germany
Leverenz, JB:
Cleveland Clin, Lou Ruvo Ctr Brain Hlth, Cleveland, OH 44106 USA
Mann, D:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth, Div Neurosci & Expt Psychol,Sch Biol Sci, Manchester, Lancs, England
Levey, AI:
Emory Univ, Dept Neurol, Atlanta, GA USA
Pickering-Brown, S:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth, Div Neurosci & Expt Psychol,Sch Biol Sci, Manchester, Lancs, England
Lieberman, AP:
Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA
Klopp, N:
Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth Neuherberg, Inst Epidemiol, Munich, Germany
Lunetta, KL:
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Wichmann, HE:
Helmholtz Ctr Munich, Inst Epidemiol, Munich, Germany
Ludwig Maximilians Univ Chair Epidemiol, Munich, Germany
Joint Biobank Munich, Baltimore, MD USA
KORA Biobank, Baltimore, MD USA
Lyketsos, CG:
Johns Hopkins Univ, Dept Psychiat, Baltimore, MD USA
Morgan, K:
Univ Nottingham, Sch Life Sci & Med, Human Genet, Nottingham, England
Marson, DC:
Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
Brown, K:
Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England
Martiniuk, F:
NYU, Dept Med Pulm, New York, NY USA
Medway, C:
Univ Nottingham, Queens Med Ctr, Inst Genet, Nottingham, England
Mash, DC:
Univ Miami, Dept Neurol, Miami, FL USA
Nothen, MM:
Univ Bonn, Inst Human Genet, Bonn, Germany
Univ Bonn, Life & Brain Ctr, Dept Genom, Bonn, Germany
Masliah, E:
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA
Hooper, NM:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth, Div Neurosci & Expt Psychol,Sch Biol Sci, Manchester, Lancs, England
McCormick, WC:
Univ Washington, Dept Med, Seattle, WA USA
Daniele, A:
Catholic Univ Sacred Hearth, Inst Neurol, Rome, Italy
McCurry, SM:
Univ Washington, Sch Nursing Northwest Res Grp Aging, Seattle, WA 98195 USA
Bayer, A:
Cardiff Univ, Univ Hosp Wales, Inst Primary Care & Publ Hlth, Cardiff, S Glam, Wales
McDavid, AN:
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
Gallacher, J:
Univ Oxford, Dept Psychiat, Oxford, England
McKee, AC:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Pathol, Boston, MA 02118 USA
van den Bussche, H:
Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany
Mesulam, M:
Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA
Northwestern Univ, Feinberg Sch Med, Dept Neurol, Chicago, IL 60611 USA
Brayne, C:
Univ Cambridge, Cambridge Inst Publ Hlth, Sch Clin Med, Cambridge, England
Miller, BL:
Univ Calif San Francisco, Memory & Aging Ctr, Weill Inst Neurosci, San Francisco, CA 94143 USA
Riedel-Heller, S:
Univ Leipzig, Inst Social Med Occupat Hlth & Publ Hlth, Leipzig, Germany
Miller, CA:
Univ Southern Calif, Dept Pathol, Los Angeles, CA USA
Miller, JW:
Univ Calif Davis, Dept Pathol & Lab Med, Sacramento, CA 95817 USA
Al-Chalabi, A:
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England
Morris, JC:
Washington Univ, Dept Pathol & Immunol, St Louis, MO USA
Washington Univ, Dept Neurol, St Louis, MO USA
Shaw, CE:
Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England
Kings Coll London, UK Dementia Res Inst, London, England
Myers, AJ:
Univ Miami, Miller Sch Med, Dept Psychiat & Behav Sci, Miami, FL 33136 USA
Wiltfang, J:
Univ Med Ctr Goettingen, Dept Psychiat & Psychotherapy, Gottingen, Germany
German Ctr Neurodegenerat Dis, Gottingen, Germany
Univ Aveiro, Med Sci Dept, IBiMED, Aveiro, Portugal
O'Bryant, S:
Univ North Texas, Hlth Sci Ctr, Dept Pharmacol & Neurosci, Ft Worth, TX USA
Olichney, JM:
Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
Alvarez, V:
Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain
Parisi, JE:
Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA
Singleton, AB:
NIA, Mol Genet Sect, Lab Neurogenet, NIH, Bethesda, MD 20892 USA
Paulson, HL:
Univ Michigan, Dept Neurol, Ann Arbor, MI USA
Michigan Alzheimer Dis Ctr, Ann Arbor, MI USA
Collinge, J:
Inst Prion Dis, MRC Prion Unit UCL, Dept Neurodegenerat Dis, London, England
Perry, WR:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Mead, S:
Inst Prion Dis, MRC Prion Unit UCL, Dept Neurodegenerat Dis, London, England
Peskind, E:
Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
Cribbs, DH:
Univ Calif Irvine, Dept Neurol, Irvine, CA 92717 USA
Rossor, M:
UCL Inst Neurol, Dept Neurodegenerat Dis, Dementia Res Ctr, London, England
Pierce, A:
Univ Calif Irvine, Dept Neurol, Irvine, CA 92717 USA
Ryan, NS:
Inst Prion Dis, MRC Prion Unit UCL, Dept Neurodegenerat Dis, London, England
Poon, WW:
Univ Calif Irvine, Inst Memory Impairments & Neurol Disorders, Irvine, CA USA
Nacmias, B:
Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy
Univ Florence, Ctr Ric Trasferimento & Alta Formaz DENOTHE, Florence, Italy
Potter, H:
Univ Colorado, Sch Med, Dept Neurol, Aurora, CO USA
Sorbi, S:
Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth, Florence, Italy
IRCCS Fdn Don Carlo Gnocchi, Florence, Italy
Quinn, JF:
Univ Med Ctr Hamburg Eppendorf, Dept Primary Med Care, Hamburg, Germany
Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA
Sacchinelli, E:
IRCCS Santa Lucia Fdn, Expt Neuropsychobiol Lab, Dept Clin & Behav Neurol, Rome, Italy
Raj, A:
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
Spalletta, G:
IRCCS Santa Lucia Fdn, Lab Neuropsychiat, Rome, Italy
Baylor Coll Med, Dept Psychiat & Behav Sci, Div Neuropsychiat, Houston, TX 77030 USA
Raskind, M:
Univ Washington, Sch Med, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
Caltagirone, C:
IRCCS Santa Lucia Fdn, Lab Neuropsychiat, Rome, Italy
Bossu, P:
IRCCS Santa Lucia Fdn, Expt Neuropsychobiol Lab, Dept Clin & Behav Neurol, Rome, Italy
Orfei, MD:
IRCCS Santa Lucia Fdn, Lab Neuropsychiat, Rome, Italy
Reisberg, B:
NYU, Dept Psychiat, 550 1St Ave, New York, NY 10016 USA
NYU, Alzheimers Dis Ctr New, New York, NY USA
Clarke, R:
Univ Oxford, Clin Trial Serv Unit, Oxford Hlth Aging Project, Oxford, England
Reitz, C:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10027 USA
Columbia Univ, Dept Epidemiol, New York, NY USA
Smith, AD:
Univ Oxford, Oxford Project Investigate Memory & Ageing, Nuffield Dept Clin Neurosci, John Radcliffe Hosp, Oxford, England
Ringman, JM:
Univ Southern Calif, Keck Sch Med, Dept Neurol, Los Angeles, CA USA
Warden, D:
Univ Oxford, Oxford Project Investigate Memory & Ageing, Nuffield Dept Clin Neurosci, John Radcliffe Hosp, Oxford, England
Roberson, ED:
Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
Wilcock, G:
Univ Oxford, Oxford Project Investigate Memory & Ageing, Nuffield Dept Clin Neurosci, John Radcliffe Hosp, Oxford, England
Rogaeva, E:
Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, Toronto, ON, Canada
Bruni, AC:
ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy
Rosen, HJ:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
Gallo, M:
ASP Catanzaro, Reg Neurogenet Ctr CRN, Lamezia Terme, Italy
Rosenberg, RN:
Univ Texas Southwestern Med Ctr Dallas, Dept Neurol, Dallas, TX 75390 USA
Ben-Shlomo, Y:
Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, Avon, England
Sager, MA:
Univ Wisconsin, Dept Med, Madison, WI USA
Mecocci, P:
Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy
Saykin, AJ:
Indiana Univ Sch Med, Indiana Alzheimers Dis Ctr, Indianapolis, IN 46202 USA
Indiana Univ, Dept Neurol, Indianapolis, IN 46204 USA
Pastor, P:
Fundacio Recerca Biomed & Social Mutua Terrassa, Barcelona, Spain
Hosp Univ Mutua Terrassa, Dept Neurol, Memory Disorders Unit, Barcelona, Spain
Cuccaro, ML:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Vance, JM:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Schneider, JA:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Pathol Neuropathol, Chicago, IL 60612 USA
Schneider, LS:
Univ Southern Calif, Dept Neurol, Los Angeles, CA USA
Univ Southern Calif, Dept Psychiat, Los Angeles, CA USA
Slifer, S:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Seeley, WW:
Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
Smith, AG:
Univ S Florida, USF Hlth Byrd Alzheimers Inst, Tampa, FL USA
Sonnen, JA:
Univ Washington, Dept Pathol, Seattle, WA 98195 USA
Spina, S:
Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA
Stern, RA:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Swerdlow, RH:
Univ Kansas, Med Ctr, Alzheimers Dis Ctr, Kansas City, KS 66103 USA
Tang, M:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Tanzi, RE:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02115 USA
Trojanowski, JQ:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Troncoso, JC:
Johns Hopkins Univ, Dept Pathol, Baltimore, MD USA
Van Deerlin, VM:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Van Eldik, LJ:
Univ Kentucky, Dept Neurosci, Sanders Brown Ctr Aging, Lexington, KY USA
Vinters, HV:
Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA USA
Vonsattel, JP:
Columbia Univ, Dept Pathol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Weintraub, S:
Northwestern Univ, Feinberg Sch Med, Mesulam Ctr Cognit Neurol & Alzheimers Dis, Chicago, IL 60611 USA
Northwestern Univ, Feinberg Sch Med, Dept Psychiat & Behav Sci, Chicago, IL 60611 USA
Welsh-Bohmer, KA:
Duke Univ, Dept Neurol, Durham, NC USA
Duke Univ, Dept Psychiat & Behav Sci, Durham, NC USA
Wilhelmsen, KC:
Univ N Carolina, Dept Genet, Chapel Hill, NC 27515 USA
Williamson, J:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Wingo, TS:
Emory Univ, Dept Neurol, Atlanta, GA USA
Emory Univ, Dept Human Genet, Atlanta, GA 30322 USA
Woltjer, RL:
Oregon Hlth & Sci Univ, Dept Pathol, Portland, OR 97201 USA
Wright, CB:
NINDS, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA
Yu, CE:
Univ Washington, Dept Med, Seattle, WA USA
Yu, L:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Saba, Y:
Med Univ Graz, Div Mol Biol & Biochem, Gottfried Schatz Res Ctr Cell Signaling Metab & A, Graz, Austria
Pilotto, A:
IRCCS Casa Sollievo Sofferenza, Gerontol & Geriatr Res Lab, San Giovanni Rotondo, Italy
Galliera Hosp, Dept Geriatr Care Orthogeriatr & Rehabil, Genoa, Italy
Bullido, MJ:
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Inst Invest Sanitaria Paz, IdiPAZ, Madrid, Spain
CSIC UAM, Ctr Biol Mol Severo Ochoa, Madrid, Spain
Peters, O:
Charite, Dept Psychiat & Psychotherapy, Berlin, Germany
German Ctr Neurodegenerat Dis, Berlin, Germany
Crane, PK:
Univ Washington, Dept Med, Seattle, WA USA
Bennett, D:
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Bosco, P:
Associaz Oasi Maria Santissima Srl, Inst Ricovero & Cura Carattere Sci, Troina, Italy
Coto, E:
Univ Cent Asturias, Mol Genet Lab Hosp, Oviedo, Spain
Boccardi, V:
Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy
De Jager, PL:
Columbia Univ, Med Ctr, Dept Neurol, Ctr Translat & Computat Neuroimmunol, New York, NY USA
Lleo, A:
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, Neurol Dept, Memory Unit, Barcelona, Spain
Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain
Warner, N:
Somerset Partnership NHS Trust, Somerset, England
Lopez, OL:
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Univ Pittsburgh, Alzheimers Dis Res Ctr, Pittsburgh, PA USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA
Ingelsson, M:
Uppsala Univ, Dept Publ Hlth & Caring Sci Geriatr, Uppsala, Sweden
Deloukas, P:
Wellcome Trust Sanger Inst, Cambridge, England
Cruchaga, C:
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
Washington Univ, Sch Med, Hope Ctr Program Prot Aggregat & Neurodegenerat, St Louis, MO USA
Graff, C:
Karolinska Univ Hosp Solna, Unit Hereditary Dementias, Theme Aging, Stockholm, Sweden
Karolinska Inst, Dept Neurobiol Care Sci & Soc, Alzheimer Res Ctr, Div Neurogeriatr, Solna, Sweden
Gwilliam, R:
Wellcome Trust Sanger Inst, Cambridge, England
Fornage, M:
Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA
Goate, AM:
Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA
Icahn Sch Med Mt Sinai, Dept Neurosci, Ronald M Loeb Ctr Alzheimers Dis, New York, NY 10029 USA
Sanchez-Juan, P:
Univ Cantabria, Marques de Valdecilla Univ Hosp, Neurol Serv, Santander, Spain
Univ Cantabria, Marques de Valdecilla Univ Hosp, CIBERNED, Santander, Spain
IDIVAL, Santander, Spain
Kehoe, PG:
Univ Bristol, Learning & Res Level 2, Med Sch, Southmead Hosp, Bristol, Avon, England
Amin, N:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Ertekin-Taner, N:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA
Berr, C:
La Colombiere Hosp, Inserm Neuropsychiat U1061, Montpellier, France
Montpellier Univ, Montpellier, France
Debette, S:
UPMC Univ Paris 06, Inst Cerveau & Moelle Epiniere, UMRS 1127, Inserm U1127,CNRS UMR 7225,Sorbonne Univ, Paris, France
Hop La Pitie Salpetriere, AP HP, Dept Genet, Paris, France
Love, S:
Univ Bristol, Learning & Res Level 2, Med Sch, Southmead Hosp, Bristol, Avon, England
Launer, LJ:
NIA, Lab Epidemiol & Populat Sci, Bethesda, MD 20892 USA
Younkin, SG:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA
Dartigues, JF:
CMRR Bordeaux, Memory Res & Resources Ctr, Bordeaux, France
Corcoran, C:
Utah State Univ, Logan, UT 84322 USA
Ikram, MA:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Erasmus MC Univ, Dept Neurol, Med Ctr, Rotterdam, Netherlands
Erasmus MC Univ, Dept Radiol, Med Ctr, Rotterdam, Netherlands
Dickson, DW:
Mayo Clin, Dept Neurosci, Jacksonville, FL 32224 USA
Nicolas, G:
Normandie Univ, UNIROUEN, Inserm U1245, Rouen, France
Rouen Univ Hosp, Dept Neurol, Dept Genet, Rouen, France
CNR MAJ, Normandy Ctr Genom & Personalized Med, Rouen, France
Campion, D:
Normandie Univ, UNIROUEN, Inserm U1245, Rouen, France
Rouen Univ Hosp, Dept Neurol, Dept Genet, Rouen, France
CNR MAJ, Normandy Ctr Genom & Personalized Med, Rouen, France
Dept Res Rouvray Psychiat Hosp, Sotteville Les Rouen, France
Tschanz, J:
Utah State Univ, Logan, UT 84322 USA
Schmidt, H:
Med Univ Graz, Div Mol Biol & Biochem, Gottfried Schatz Res Ctr Cell Signaling Metab & A, Graz, Austria
Med Univ Graz, Dept Neurol, Graz, Austria
Hakonarson, H:
Univ Penn, Perelman Sch Med, Childrens Hosp Philadelphia, Ctr Appl Genom, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Dept Pediat, Div Human Genet, Philadelphia, PA 19104 USA
Clarimon, J:
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, Neurol Dept, Memory Unit, Barcelona, Spain
Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, St Pau Biomed Res Inst, Barcelona, Spain
Munger, R:
Utah State Univ, Logan, UT 84322 USA
Schmidt, R:
Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria
Farrer, LA:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Boston Univ, Sch Med, Dept Med Biomed Genet, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Ophthalmol, Boston, MA 02215 USA
Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
Van Broeckhoven, C:
VIB, Ctr Mol Neurol, Neurodegenerat Brain Dis Grp, Antwerp, Belgium
Univ Antwerp, Inst Born Bunge, Lab Neurogenet, Antwerp, Belgium
O'Donovan, MC:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
DeStefano, AL:
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
Jones, L:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Haines, JL:
Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Inst Computat Biol, Cleveland, OH 44106 USA
Deleuze, JF:
Univ Paris Saclay, CEA, Inst Biol Francois Jacob, Ctr Natl Rech Genom Humaine, Evry, France
LabEx GENMED, Evry, France
Owen, MJ:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Gudnason, V:
Iceland Heart Assoc, Kopavogur, Iceland
Univ Iceland, Fac Med, Reykjavik, Iceland
Mayeux, R:
Columbia Univ, Dept Neurol, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10027 USA
Columbia Univ, Dept Neurol, New York, NY USA
Escott-Price, V:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Psaty, BM:
Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA
Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA
Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA
Ramirez, A:
Univ Hosp Bonn, Dept Neurodegenerat Dis & Geriatr Psychiat, Bonn, Germany
Univ Cologne, Dept Psychiat & Psychotherapy, Cologne, Germany
Wang, LS:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Ruiz, A:
Univ Int Catalunya, Inst Catala Neurociencies Aplicades, Res Ctr & Memory Clin Fundacio ACE, Barcelona, Spain
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain
van Duijn, CM:
Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
Holmans, PA:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Seshadri, S:
Framingham Heart Dis Epidemiol Study, Framingham, MA USA
Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
Glenn Biggs Inst Alzheimers & Neurodegenerat Dis, San Antonio, TX USA
Williams, J:
Cardiff Univ, MRC Ctr Neuropsychiat Genet & Genom, Div Psychol Med & Clin Neurosci, Cardiff, S Glam, Wales
Cardiff Univ, UK Dementia Res Inst Cardiff, Cardiff, S Glam, Wales
Amouyel, P:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
CHU Lille, Lille, France
Schellenberg, GD:
Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, Penn Neurodegenerat Genom Ctr, Philadelphia, PA 19104 USA
Lambert, JC:
Inserm, RID AGE Risk Factors & Mol Determinants Aging Rel, U1167, Lille, France
Inst Pasteur, Lille, France
Univ Lille, U1167, Excellence Lab LabEx DISTALZ, Lille, France
Pericak-Vance, MA:
Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL 33136 USA
Green Accepted
|