Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study


Por: Lopez-Alcalde, J, Stallings, E, Nunes, SC, Chavez, AF, Daheron, M, Cosp, XB, Zamora, J

Publicada: 15 mar 2019
Resumen:
BackgroundHealthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will limit their applicability and capacity to support informed decisions. This study aims to describe the extent to which Cochrane reviews of interventions for preventing HAIs consider sex and gender.MethodsMethodology study appraising Cochrane reviews of interventions to prevent HAIs. Search methods: Cochrane Database of Systematic Reviews from 1995 (launch of the journal) to 31 December 2016. Two authors independently extracted data with EPPI-Reviewer 4 software, and independently appraised the sex/gender content of the reviews with the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR).ResultsThis study included 113 reviews assessing the effects of interventions for preventing HAIs. 100 reviews (88%) used at least one sex or gender-related term. The terminology used was heterogeneous, being sex the term used in more reviews (51%). No review defined neither sex nor gender. Thus we could not assess the definitions provided. Consideration of sex and gender was practically absent in the included reviews; in fact, no review met all the applicable items of the SGAT-SR, and 51 reviews (50%) fulfilled no item. No review provided a complete description of the sex and the gender of the samples of the included studies. Only ten reviews (10%) planned to perform sex- and gender-based analysis and only three (3%) could complete the analysis. The method chosen was always the subgroup analysis based on sex (one review) or gender (two reviews). Three reviews (3%) considered sex or gender-related findings in the conclusions.ConclusionConsideration of sex and gender in Cochrane reviews of interventions for preventing HAIs was practically absent. This lack of attention to sex and gender reduces the quality of Cochrane reviews, and their applicability for all people: women and men, boys and girls, and people of diverse gender identities. Cochrane should attempt to address the shortfalls detected.

Filiaciones:
Lopez-Alcalde, J:
 Univ Autonoma Barcelona, Dept Paediat Obstet & Gynaecol & Preventat Med, Barcelona, Spain

 Univ Francisco Vitoria UFV Madrid, Fac Hlth Sci, Madrid, Spain

 Hosp Univ Ramon y Cajal IRYCIS, Clin Biostat Unit, Madrid, Spain

 Cochrane Associate Ctr Madrid, Madrid, Spain

Stallings, E:
 Hosp Univ Ramon y Cajal IRYCIS, Clin Biostat Unit, Madrid, Spain

Chavez, AF:
 Hosp Univ Ramon y Cajal, Prevent Med Unit, Madrid, Spain

Cosp, XB:
 Univ Autonoma Barcelona, IIB St Pau, Iberoamer Cochrane Ctr, Madrid, Spain

 CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain

Zamora, J:
 Hosp Univ Ramon y Cajal IRYCIS, Clin Biostat Unit, Madrid, Spain

 CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain
ISSN: 14726963
Editorial
BMC, CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 19 Número:
Páginas:
WOS Id: 000461364400001
ID de PubMed: 30876452
imagen Gold, Green Published

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