Gender Differences in Response to Metacognitive Training in People With First-Episode Psychosis
Por:
Salas-Sender, M, Lopez-Carrilero, R, Barajas, A, Lorente-Rovira, E, Pousa, E, Barrigon, ML, Grasa, E, Ruiz-Delgado, I, Gonzalez-Higueras, F, Cid, J, Aznar, A, Pelaez, T, Birules, I, Moritz, S, Ochoa, S
Publicada:
1 jun 2020
Resumen:
Introduction: The study aimed to assess gender differences in the efficacy of metacognitive training (MCT) in people with first-episode psychosis in terms of symptoms and cognitive insight as a primary outcome and other metacognitive and social cognition measures as a secondary outcome. Method: A multicenter, controlled, randomized clinical trial was performed including 122 patients with first-episode psychosis. A total of 8 weekly group sessions of MCT or a psychoeducational intervention were performed. Patients were assessed at baseline. posttreatment, and follow-up. Symptoms were assessed with the Positive and Negative Syndrome Scale and cognitive insight with the Beck Cognitive Insight Scale. A battery of questionnaires on metacognition and social cognition variables was included to assess secondary outcomes. A regression model for repeated measures was performed by gender. Results: Women of the MCT group improved more in general symptoms (p = .046). self-certainty (p = .010), and a composite index of the cognitive insight (p = .031). Moreover, women in the MCT group showed a reduction in personalizing bias (p = .021) and irrational beliefs related to dependence (p = .024), while men in the MCI group showed an improvement in intolerance to frustration (p = .017). In the Jumping to Conclusions task, men in the MCI group improved in the affective task (p = .021) while no differences were found in women. Conclusions: Our results suggest that MCT is more effective in reducing symptoms and improving cognitive insight for women than men. Moreover, different irrational beliefs and cognitive biases were reduced differently considering gender. MCT could be a gender-sensitive intervention.
Filiaciones:
Salas-Sender, M:
Parc Sanitari St Joan de Deu, Barcelona, Spain
Lopez-Carrilero, R:
Parc Sanitari St Joan de Deu, Res Inst St Joan de Deu, C Pujades 42, Barcelona 08033, Spain
CIBERSAM, Madrid, Spain
Barajas, A:
Ctr Higiene Mental Le Corts, Barcelona, Spain
Univ Autonoma Barcelona, Dept Personal Evaluat & Psychol Treatment, Barcelona, Spain
Lorente-Rovira, E:
CIBERSAM, Madrid, Spain
Hosp Clin Univ Valencia, Valencia, Spain
Pousa, E:
Hosp Santa Creu & Sant Pau, Dept Psychiat, Inst Invest Biomed St Pau IIBSt Pau, Barcelona, Spain
Univ Autonoma Barcelona, Salut Mental Parc Tauli, Barcelona, Spain
Barrigon, ML:
Univ Autonoma Madrid, Dept Psychiat, Fdn IIS Jimenez Diaz, Madrid, Spain
Area Gest Sanitaria Sur Granada, Psychiat Serv, Granada, Spain
Grasa, E:
CIBERSAM, Madrid, Spain
Hosp Santa Creu & Sant Pau, Dept Psychiat, Biomed St Pau Res Inst IIBSt Pau, Barcelona, Spain
Ruiz-Delgado, I:
UGC Salud Mental Carlos Haya, Community Mental Hlth Unit Malaga Norte, Serv Andaluz Salud, Malaga, Spain
Gonzalez-Higueras, F:
UGC Salud Mental Jaen, Therapeut Community, Serv Andaluz Salud, Jaen, Spain
Cid, J:
Inst Assistencia Sanitaria, Girona, Spain
Aznar, A:
Ctr Higiene Mental Les Corts, Barcelona, Spain
Pelaez, T:
Parc Sanitari St Joan de Deu, Res Inst St Joan de Deu, C Pujades 42, Barcelona 08033, Spain
CIBERSAM, Madrid, Spain
Birules, I:
Parc Sanitari St Joan de Deu, Res Inst St Joan de Deu, C Pujades 42, Barcelona 08033, Spain
CIBERSAM, Madrid, Spain
Moritz, S:
Univ Med Ctr Hamburg, Dept Psychiat & Psychotherapy, Hamburg, Germany
Ochoa, S:
Parc Sanitari St Joan de Deu, Res Inst St Joan de Deu, C Pujades 42, Barcelona 08033, Spain
CIBERSAM, Madrid, Spain
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