Estimating the impact of obesity and metabolic phenotype on sickness absence. Results from the ICARIA study


Por: Catalina-Romero, C, Chaparro, MAS, Valdivielso, R, Quevedo-Aguado, L, Brotons, C, Ruilope, LM, Calvo-Bonacho, E

Publicada: 1 abr 2019
Resumen:
Background and aims: To assess the impact of obesity and being overweight on sickness absence (SA) as a function of healthy/unhealthy metabolic phenotype. Methods and results: A total of 173 120 healthy workers who underwent a routine check-up, consisting of a structured interview, anthropometric measurements and blood pressure and fasting blood analysis, were included as the study sample (67.1% males; 49.2% manual workers; mean age 40.6 +/- 21.9 years). Workers were classified according to their body mass index (BMI) and metabolic phenotype. A metabolically unhealthy phenotype was defined as the presence of three or more of the following criteria: glycaemia >= 110 mg/dL or previously diagnosed type I/II diabetes or treatment for diabetes; triglycerides >= 150 mg/dL or lipid-lowering therapy; HDL <40/ 50 mg/dL M/F; blood pressure >= 130/85 mmHg or previously diagnosed hypertension or antihy-pertensive therapy; waist circumference >102/88 cm M/F. A one-year follow-up was conducted to evaluate the incidence of work-related and non-work-related SA (WRSA/NWRSA). The association of BMI with SA was tested using Poisson regression (standard error correction), segmenting on the basis of metabolic phenotype. The overall percentages of workers who were overweight, obese and/or had a metabolically unhealthy phenotype were 37.7%, 16.3% and 8.8%, respectively. BMI was associated with increased incidence of NWRSA in both phenotypes. It was also associated with WRSA in subjects with a BMI in the range of 35-39.99 kg/m(2)and in metabolically healthy individuals. WRSA was lower in subjects with a BMI >= 40 kg/m(2)and among metabolically unhealthy individuals. Conclusion: Obesity is associated with health problems that have a significant impact on SA. (C) 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Filiaciones:
Catalina-Romero, C:
 Ibermutuamur Mutua Colaboradora Seguridad Social, Madrid, Spain

Chaparro, MAS:
 Univ Hosp Virgen de la Victoria, Dept Internal Med, Malaga, Spain

 Univ Malaga, Malaga, Spain

Valdivielso, R:
 Univ Hosp Virgen de la Victoria, Dept Internal Med, Malaga, Spain

 Univ Malaga, Malaga, Spain

Quevedo-Aguado, L:
 Ibermutuamur Mutua Colaboradora Seguridad Social, Madrid, Spain

Brotons, C:
 Biomed Res Inst St Pau, IIB St Pau, Sardenya Primary Hlth Care Ctr, Res Unit, Barcelona, Spain

Ruilope, LM:
 Res Inst Hosp 12 Octubre, Madrid, Spain

Calvo-Bonacho, E:
 Ibermutuamur Mutua Colaboradora Seguridad Social, Madrid, Spain
ISSN: 09394753





NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Editorial
ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, Italia
Tipo de documento: Article
Volumen: 29 Número: 4
Páginas: 383-389
WOS Id: 000461777400009
ID de PubMed: 30803866

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