Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections in Leukemia (ECIL)
Por:
Maschmeyer, G, De Greef, J, Mellinghoff, SC, Nosari, A, Thiebaut-Bertrand, A, Bergeron, A, Franquet, T, Blijlevens, NMA, Maertens, JA, ECIL
Publicada:
1 abr 2019
Resumen:
A multitude of new agents for the treatment of hematologic malignancies has been introduced over the past decade. Hematologists, infectious disease specialists, stem cell transplant experts, pulmonologists and radiologists have met within the framework of the European Conference on Infections in Leukemia (ECIL) to provide a critical state-of-the-art on infectious complications associated with immunotherapeutic and molecular targeted agents used in clinical routine. For brentuximab vedotin, blinatumomab, CTLA4- and PD-1/PD-L1-inhibitors as well as for ibrutinib, idelalisib, HDAC inhibitors, mTOR inhibitors, ruxolitinib, and venetoclax, a detailed review of data available until August 2018 has been conducted, and specific recommendations for prophylaxis, diagnostic and differential diagnostic procedures as well as for clinical management have been developed.
Filiaciones:
Maschmeyer, G:
Klinikum Ernst von Bergmann, Dept Hematol Oncol & Palliat Care, Charlottenstr 72, D-14467 Potsdam, Germany
De Greef, J:
Catholic Univ Louvain, St Luc Univ Hosp, Dept Internal Med & Infect Dis, Brussels, Belgium
Henri Mondor Teaching Hosp, AP HP, Dept Hematol, Creteil, France
Mellinghoff, SC:
Univ Hosp Cologne, Dept Internal Med 1, Cologne, Germany
Univ Cologne, Cologne Excellence Cluster Cellular Stress Respon, Cologne, Germany
Nosari, A:
ASST Grande Osped Metropolitano Niguarda, Dept Hematol, Milan, Italy
Thiebaut-Bertrand, A:
Univ Grenoble Alpes, Dept Hematol, Grenoble, France
Bergeron, A:
Univ Paris Diderot, St Louis Hosp, AP HP, Dept Pneumol, Paris, France
Franquet, T:
Hosp Santa Creu & Sant Pau, Dept Radiol, Barcelona, Spain
Blijlevens, NMA:
Radboud Univ Nijmegen, Med Ctr, Dept Hematol, Nijmegen, Netherlands
Maertens, JA:
Univ Hosp Leuven, Dept Hematol, Leuven, Belgium
Univ Leuven, Dept Microbiol & Immunol, Leuven, Belgium
Green Published, Hybrid Gold
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