Is vitamin-D supplementation not useful in patients at risk of fractures and falls?
Por:
del Rey, JA, Gimeno, EJ, Baztan, FB, Alonso, CG, Lama, YG, Sierra, JM, Borrego, RS, de la Morena, JS, Perez, JAS, Llorca, CVY
Publicada:
1 feb 2020
Ahead of Print:
1 ago 2019
Resumen:
To evaluate numerous publications that question the bone and extraosseous benefits of vitamin D diet supplementation based on results, which often transcend to public opinion, but are not well interpreted. This may have negative consequences on compliance of patients under vitamin D supplementation. Critical appraisal of several articles on vitamin D supplementation and its relationship with fractures, falls, cardiovascular diseases, and cancer incidence. Such publications have certain limitations (i.e. patients excluded because of a diagnosis of osteoporosis, or at a higher risk for fractures and falls, or because they have a vitamin D deficiency, etc.), and conclusions and/or subsequent recommendations should be approached with caution. Our research shows that patients with osteoporosis, vitamin D deficiency, and at high risk of fractures and falls should not discontinue vitamin D supplementation (often associated with calcium). It is becoming increasingly evident that patients with hypovitaminosis D are those that gain a maximal benefit from vitamin D supplementation.
Filiaciones:
del Rey, JA:
Hosp Clin Virgen Victoria, Serv Reumatol, Malaga, Spain
Gimeno, EJ:
Hosp Univ Quironsalud, Serv Endocrinol, Madrid, Spain
Baztan, FB:
Hosp Univ Infanta Leonor, Secc Geriatria, Madrid, Spain
Alonso, CG:
Hosp Univ Cent Asturias, Serv Metab Oseo & Mineral, Oviedo, Spain
Lama, YG:
Hosp Univ Puerta Hierro, Serv Gastroenterol & Hepatol, Madrid, Spain
Sierra, JM:
Hosp Santa Creu & Sant Pau, Unidad Metab Mineral, Dept Med Interna, Barcelona, Spain
Borrego, RS:
DIATROS, Clin Atenc Mujer, Barcelona, Spain
de la Morena, JS:
Hosp Univ 12 Octubre, Serv Nefrol, Madrid, Spain
Perez, JAS:
Hosp Univ Virgen Victoria, Serv Dermatol, Malaga, Spain
Llorca, CVY:
SERMAS, Ctr Salud Fuencarral, Med Familia, Madrid, Spain
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