Patterns of Red and Processed Meat Consumption and Risk for Cardiometabolic and Cancer Outcomes A Systematic Review and Meta-analysis of Cohort Studies
Por:
Vernooij, RWM, Zeraatkar, D, Han, MA, El Dib, R, Zworth, M, Milio, K, Sit, D, Lee, Y, Gomaa, H, Valli, C, Swierz, MJ, Chang, YP, Hanna, SE, Brauer, PM, Sievenpiper, J, de Souza, R, Alonso-Coello, P, Bala, MM, Guyatt, GH, Johnston, BC
Publicada:
19 nov 2019
Resumen:
Background: Studying dietary patterns may provide insights into the potential effects of red and processed meat on health outcomes.
Purpose: To evaluate the effect of dietary patterns, including different amounts of red or processed meat, on all-cause mortality, cardiometabolic outcomes, and cancer incidence and mortality.
Data Sources: Systematic search of MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, CINAHL, Web of Science, and ProQuest Dissertations & Theses Global from inception to April 2019 with no restrictions on year or language.
Study Selection: Teams of 2 reviewers independently screened search results and included prospective cohort studies with 1000 or more participants that reported on the association between dietary patterns and health outcomes.
Data Extraction: Two reviewers independently extracted data, assessed risk of bias, and evaluated the certainty of evidence using GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria.
Data Synthesis: Eligible studies that followed patients for 2 to 34 years revealed low- to very-low-certainty evidence that dietary patterns lower in red and processed meat intake result in very small or possibly small decreases in all-cause mortality, cancer mortality and incidence, cardiovascular mortality, nonfatal coronary heart disease, fatal and nonfatal myocardial infarction, and type 2 diabetes. For all-cause, cancer, and cardiovascular mortality and incidence of some types of cancer, the total sample included more than 400 000 patients; for other outcomes, total samples included 4000 to more than 300 000 patients.
Limitation: Observational studies are prone to residual confounding, and these studies provide low- or very-low-certainty evidence according to the GRADE criteria.
Conclusion: Low- or very-low-certainty evidence suggests that dietary patterns with less red and processed meat intake may result in very small reductions in adverse cardiometabolic and cancer outcomes.
Primary Funding Source: None. (PROSPERO: CRD42017074074)
Filiaciones:
Vernooij, RWM:
Netherlands Comprehens Canc Org, Utrecht, Netherlands
Dalhousie Univ, Halifax, NS, Canada
Netherlands Comprehens Canc Org, Dept Res, Godebaldkwartier 419, NL-3511 DT Utrecht, Netherlands
Zeraatkar, D:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Han, MA:
Chosun Univ, Gwangju, South Korea
Chosun Univ, Sch Med, Dept Prevent Med, 309 Philmum Daero, Gwangju 61452, South Korea
El Dib, R:
Dalhousie Univ, Halifax, NS, Canada
Univ Estadual Paulista, Sao Paulo, Brazil
Univ Estadual Paulista, Inst Sci & Technol, Ave Engenheiro Francisco Jose Longo 777, BR-12245000 Sao Paulo, Brazil
Zworth, M:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, Hlth Sci Ctr, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
Milio, K:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, Hlth Sci Ctr, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
Sit, D:
Univ British Columbia, 107-1165 West 13th Ave, Vancouver, BC V6H 1N4, Canada
Lee, Y:
McMaster Univ, Hamilton, ON, Canada
Gomaa, H:
Alexandria Univ, Alexandria, Egypt
Minist Hlth, Tanta Chest Hosp, Tanta, Egypt
Alexandria Univ, High Inst Publ Hlth, Dept Biostat, 165 El Horreya Ave, Alexandria, Egypt
Valli, C:
Biomed Res Inst San Pau IIB St Pau, Iberoamer Cochrane Ctr, Barcelona, Spain
Iberoamer Cochrane Ctr, Carrer St Antoni Maria Claret 167, Barcelona 08025, Spain
Swierz, MJ:
Jagiellonian Univ, Coll Med, Krakow, Poland
Jagiellonian Univ, Dept Hyg & Dietet, Coll Med, Kopernika 7,31-034, PL-30019 Krakow, Poland
Chang, YP:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Hanna, SE:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, Dept Hlth Res Methods Evidence & Impact, 1280 Main St West, Hamilton, ON L8S 4K1, Canada
Brauer, PM:
Univ Guelph, Guelph, ON, Canada
Univ Guelph, Dept Family Relat & Appl Nutr, 50 Stone Rd East, Guelph, ON N1G 2W1, Canada
Sievenpiper, J:
Univ Toronto, Toronto, ON, Canada
St Michaels Hosp, Toronto, ON, Canada
St Michaels Hosp, 6138-61 Queen St East, Toronto, ON M5C 2T2, Canada
de Souza, R:
McMaster Univ, Hamilton, ON, Canada
McMaster Univ, MDCL, 1280 Main St West,Room 3210, Hamilton, ON L8S 4K1, Canada
Alonso-Coello, P:
Biomed Res Inst San Pau IIB St Pau, Iberoamer Cochrane Ctr, Barcelona, Spain
CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain
Iberoamer Cochrane Ctr, Carrer St Antoni Maria Claret 167, Barcelona 08025, Spain
Bala, MM:
Jagiellonian Univ, Coll Med, Krakow, Poland
Jagiellonian Univ, Coll Med, Chair Epidemiol & Prevent Med, Dept Hyg & Dietet, Kopernika 7, PL-30019 Krakow, Poland
Guyatt, GH:
McMaster Univ, Hamilton, ON, Canada
Johnston, BC:
Dalhousie Univ, Halifax, NS, Canada
McMaster Univ, Hamilton, ON, Canada
Texas A&M Univ, College Stn, TX USA
Dalhousie Univ, Dept Community Hlth & Epidemiol, Fac Med, Room 404,5790 Univ Ave, Halifax, NS B3J 0E4, Canada
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