The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have We Learned from the DALI Studies?


Por: Harreiter, J, Desoye, G, van Poppel, MNM, Kautzky-Willer, A, Dunne, F, Corcoy, R, Devlieger, R, Simmons, D, Adelantado, JM, Damm, P, Mathiesen, ER, Jensen, DM, Anderson, LLT, Lapolla, A, Dalfra, MG, Bertolotto, A, Wender-Ozegowska, E, Zawiejska, A, Hill, DJ, Snoek, FJ, DALI Consortium

Publicada: 1 dic 2019
Resumen:
Purpose of Review The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDMwith lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI >= 29 kg/m(2). Recent Findings Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Summary Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.

Filiaciones:
Harreiter, J:
 Med Univ Vienna, Div Endocrinol & Metab, Dept Med 3, Gender Med Unit, Vienna, Austria

Desoye, G:
 Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria

van Poppel, MNM:
 Karl Franzens Univ Graz, Inst Sport Sci, Graz, Austria

 Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Publ & Occupat Hlth, Amsterdam, Netherlands

Kautzky-Willer, A:
 Med Univ Vienna, Div Endocrinol & Metab, Dept Med 3, Gender Med Unit, Vienna, Austria

Dunne, F:
 Natl Univ Ireland, Galway, Ireland

Corcoy, R:
 Hosp Santa Creu & Sant Pau, Inst Recerca, Barcelona, Spain

 Inst Salud Carlos III, CIBER Bioengn Biomat & Nanotechnol, Madrid, Spain

 Univ Autonoma Barcelona, Dept Med, Bellaterra, Spain

Devlieger, R:
 Katholieke Univ Leuven, Univ Hosp Leuven, Dept Dev & Regenerat Pregnancy Fetus & Neonate Gy, Leuven, Belgium

Simmons, D:
 Addenbrookes Hosp, Inst Metab Sci, Cambridge, England

 Western Sydney Univ, Sch Med, Macarthur Clin Sch, Locked Bag 1797, Campbelltown, NSW 2751, Australia

Adelantado, JM:
 Hosp Santa Creu & Sant Pau, Inst Recerca, Barcelona, Spain

Damm, P:
 Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Endocrinol, Copenhagen, Denmark

 Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Obstet, Copenhagen, Denmark

Mathiesen, ER:
 Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Endocrinol, Copenhagen, Denmark

 Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Obstet, Copenhagen, Denmark

Jensen, DM:
 Odense Univ Hosp, Dept Endocrinol, Odense, Denmark

 Odense Univ Hosp, Dept Obstet & Gynaecol, Odense, Denmark

 Univ Southern Denmark, Dept Clin Res, Fac Hlth Sci, Odense, Denmark

Anderson, LLT:
 Odense Univ Hosp, Dept Endocrinol, Odense, Denmark

 Odense Univ Hosp, Dept Obstet & Gynaecol, Odense, Denmark

 Univ Southern Denmark, Dept Clin Res, Fac Hlth Sci, Odense, Denmark

Lapolla, A:
 Univ Padua, Padua, Italy

Dalfra, MG:
 Univ Padua, Padua, Italy

Bertolotto, A:
 Azienda Osped Univ Pisana, Pisa, Italy

Wender-Ozegowska, E:
 Poznan Univ Med Sci, Div Reprod, Poznan, Poland

Zawiejska, A:
 Poznan Univ Med Sci, Div Reprod, Poznan, Poland

Hill, DJ:
 Rech Sante Lawson SA, St Gallen, Switzerland

Snoek, FJ:
 Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Med Psychol, Amsterdam, Netherlands

 AMC, Med Psychol, Amsterdam, Netherlands
ISSN: 15344827
Editorial
CURRENT MEDICINE GROUP, 400 MARKET STREET, STE 700, PHILADELPHIA, PA 19106 USA, Estados Unidos America
Tipo de documento: Review
Volumen: 19 Número: 12
Páginas:
WOS Id: 000510481300004
ID de PubMed: 31845115
imagen Green Published

MÉTRICAS