The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have We Learned from the DALI Studies?
Por:
Harreiter, J, Desoye, G, van Poppel, MNM, Kautzky-Willer, A, Dunne, F, Corcoy, R, Devlieger, R, Simmons, D, Adelantado, JM, Damm, P, Mathiesen, ER, Jensen, DM, Anderson, LLT, Lapolla, A, Dalfra, MG, Bertolotto, A, Wender-Ozegowska, E, Zawiejska, A, Hill, DJ, Snoek, FJ, DALI Consortium
Publicada:
1 dic 2019
Resumen:
Purpose of Review The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDMwith lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI >= 29 kg/m(2).
Recent Findings Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation.
Summary Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.
Filiaciones:
Harreiter, J:
Med Univ Vienna, Div Endocrinol & Metab, Dept Med 3, Gender Med Unit, Vienna, Austria
Desoye, G:
Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
van Poppel, MNM:
Karl Franzens Univ Graz, Inst Sport Sci, Graz, Austria
Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Publ & Occupat Hlth, Amsterdam, Netherlands
Kautzky-Willer, A:
Med Univ Vienna, Div Endocrinol & Metab, Dept Med 3, Gender Med Unit, Vienna, Austria
Dunne, F:
Natl Univ Ireland, Galway, Ireland
Corcoy, R:
Hosp Santa Creu & Sant Pau, Inst Recerca, Barcelona, Spain
Inst Salud Carlos III, CIBER Bioengn Biomat & Nanotechnol, Madrid, Spain
Univ Autonoma Barcelona, Dept Med, Bellaterra, Spain
Devlieger, R:
Katholieke Univ Leuven, Univ Hosp Leuven, Dept Dev & Regenerat Pregnancy Fetus & Neonate Gy, Leuven, Belgium
Simmons, D:
Addenbrookes Hosp, Inst Metab Sci, Cambridge, England
Western Sydney Univ, Sch Med, Macarthur Clin Sch, Locked Bag 1797, Campbelltown, NSW 2751, Australia
Adelantado, JM:
Hosp Santa Creu & Sant Pau, Inst Recerca, Barcelona, Spain
Damm, P:
Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Endocrinol, Copenhagen, Denmark
Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Obstet, Copenhagen, Denmark
Mathiesen, ER:
Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Endocrinol, Copenhagen, Denmark
Univ Copenhagen, Rigshosp, Fac Hlth & Med Sci,Inst Clin Med, Ctr Pregnant Women Diabet,Dept Obstet, Copenhagen, Denmark
Jensen, DM:
Odense Univ Hosp, Dept Endocrinol, Odense, Denmark
Odense Univ Hosp, Dept Obstet & Gynaecol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Fac Hlth Sci, Odense, Denmark
Anderson, LLT:
Odense Univ Hosp, Dept Endocrinol, Odense, Denmark
Odense Univ Hosp, Dept Obstet & Gynaecol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Fac Hlth Sci, Odense, Denmark
Lapolla, A:
Univ Padua, Padua, Italy
Dalfra, MG:
Univ Padua, Padua, Italy
Bertolotto, A:
Azienda Osped Univ Pisana, Pisa, Italy
Wender-Ozegowska, E:
Poznan Univ Med Sci, Div Reprod, Poznan, Poland
Zawiejska, A:
Poznan Univ Med Sci, Div Reprod, Poznan, Poland
Hill, DJ:
Rech Sante Lawson SA, St Gallen, Switzerland
Snoek, FJ:
Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Med Psychol, Amsterdam, Netherlands
AMC, Med Psychol, Amsterdam, Netherlands
Green Published
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