Second-generation preimplantation genetic testing for aneuploidy in assisted reproduction: a SWOT analysis


Por: Bellver, J, Bosch, E, Espinos, JJ, Fabregues, F, Fontes, J, Garcia-Velasco, J, Llacer, J, Requena, A, Checa, MA

Publicada: 1 dic 2019
Resumen:
Second-generation preimplantation genetic testing for aneuploidy (PGT-A 2.0) in patients with an unfavourable reproductive and IVF prognosis is becoming common practice, with the aim of improving reproductive outcomes. However, there is still no clear evidence on the possible advantages and drawbacks with regard to this procedure. In this discussion paper, based on a SWOT (strengths, weaknesses, opportunities, threats) analysis, the different aspects of this strategy are evaluated. Current evidence suggests that PGT-A 2.0 should not at present have an indiscriminate application, but it might be indicated in cases in which the risk of aneuploidy is increased.

Filiaciones:
Bellver, J:
 Univ Valencia, Fac Med, Inst Valenciano Infertilidad, Valencia, Spain

 Univ Valencia, Fac Med, Dept Pediat Obstet & Ginecol, Valencia, Spain

Bosch, E:
 Univ Valencia, Fac Med, Inst Valenciano Infertilidad, Valencia, Spain

 Univ Valencia, Fac Med, Dept Pediat Obstet & Ginecol, Valencia, Spain

Espinos, JJ:
 Fertty, Barcelona, Spain

 Hosp Santa Creu & Sant Pau, Barcelona, Spain

Fabregues, F:
 Hosp Clin Barcelona, Inst Clin Gynecol Obstet & Neonatol, Barcelona, Spain

Fontes, J:
 Hosp Univ Virgen de las Nieves, Granada, Spain

Garcia-Velasco, J:
 IVI RMA Madrid, Madrid, Spain

Llacer, J:
 Inst Bernabeu Alicante, Alicante, Spain

Requena, A:
 IVI RMA Madrid, Madrid, Spain

Checa, MA:
 Hosp del Mar, Parc Salut Mar, Barcelona, Spain
ISSN: 14726483





REPRODUCTIVE BIOMEDICINE ONLINE
Editorial
ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, Reino Unido
Tipo de documento: Review
Volumen: 39 Número: 6
Páginas: 905-915
WOS Id: 000502337600004
ID de PubMed: 31653432
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