Chronic Diabetes Complications: The Need to Move beyond Classical Concepts
Por:
Mauricio, D, Alonso, N, Gratacos, M
Publicada:
1 abr 2020
Resumen:
Chronic-diabetes-related complications simultaneously compromise both the micro- and macrovascular trees, with target organs considered as the paradigm of large vessel injury also entailing microangiopathic changes. However, complications independent or partially independent from vascular damage are often overlooked. This includes neuronal dysfunction (e.g., retinal neurodegeneration), interstitial injury (e.g., tubulointerstitial disease), metabolic damage (e.g., in the heart and liver), and nonclassical conditions such as cognitive decline, impaired pulmonary function, or increased risk of cancer. In this scenario, researchers, endocrinologists and primary care physicians should have a holistic view of the disease and pay further attention to all organs and all potential clinical repercussions, which would certainly contribute to a more rational and integrated patient health care.
Filiaciones:
Mauricio, D:
Fundacio Inst Univ Recerca Atencio Primaria Salut, Unitat Suport Recerca Barcelona, DAP Cat Grp, Barcelona, Spain
ISCIII, CIBER Diabet & Associated Metab Dis CIBERDEM, Barcelona, Spain
Autonomous Univ Barcelona, Hosp Santa Creu & St Pau, Dept Endocrinol & Nutr, Barcelona, Spain
Alonso, N:
ISCIII, CIBER Diabet & Associated Metab Dis CIBERDEM, Barcelona, Spain
Hlth Sci Res Inst, Dept Endocrinol & Nutr, Badalona, Spain
Univ Hosp Germans Trias & Pujol, Badalona, Spain
Gratacos, M:
Fundacio Inst Univ Recerca Atencio Primaria Salut, Unitat Suport Recerca Barcelona, DAP Cat Grp, Barcelona, Spain
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