GradCAM as an explicability method to evaluate the performance of deep learning models in classifying pediatric arteriovenous malformations (AVM) in arterial spin labeling sequences (ASL)


Por: Romagosa, J, Mata, C, Benítez, R, Valls-Esteve, A, Bernaus, S, Ibnoulkhatib, M, Stephan-Otto, C, Munuera, J

Publicada: 20 oct 2025
Resumen:
PurposeThe study investigates the usefulness of Convolutional Neural Networks (CNNs) in accurately detecting arteriovenous malformations in pediatric medical imaging, particularly using arterial spin labeling sequences. It also aims to offer diagnostic explanations comparable to expert analysis.MethodsThe research analyzed three different CNN architectures to determine their performance in detecting arteriovenous malformations. The study focused on evaluating the relationship between model complexity and performance increase, using data to assess the accuracy and diagnostic usefulness of each model.ResultsThe findings indicated a nonlinear link between model complexity and performance. Sur- prisingly, more complex models frequently produced poor results and diagnostically useless answers. The simplest CNN models achieved the highest accuracy rate (90%), demonstrating the effectiveness of minimal complexity in model construction. Heat maps showed a strong association with the real locations of irregularities, indicating that the models were interpretable.ConclusionThe study highlights the usefulness of CNNs in medical diagnostics, emphasizing the importance of model simplicity and interpretability in clinical applications. It suggests a need for balancing technical sophistication with clinical value and presents options for future research into refining CNN structures for increased diagnostic precision in various medical imaging modalities.

Filiaciones:
Romagosa, J:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

Mata, C:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

 Univ Politecn Cataluna, Inst Res & Innovat Hlth IRIS, BIOCOM SC, Barcelona, Spain

Benítez, R:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

 Univ Politecn Cataluna, Inst Res & Innovat Hlth IRIS, BIOCOM SC, Barcelona, Spain

Valls-Esteve, A:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

 Hosp San Juan Dios, Innovat Dept, Esplugues Del Llobregat, Spain

Bernaus, S:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

Ibnoulkhatib, M:
 Hosp San Juan Dios, Dept Diagnost Imaging, Esplugues Del Llobregat, Spain

Stephan-Otto, C:
 Inst Recerca Sant Joan de Deu, Pediat Computat Imaging Ctr, Esplugas de Llobregat, Spain

 Ctr Invest Biomed Red Salud Mental, Madrid, Spain

Munuera, J:
 Inst Recerca Sant Pau, Adv Med Imaging Artificial Intelligence & Imaging, Barcelona, Spain

 Hosp Santa Creu & Sant Pau, Diagnost Imaging Dept, Barcelona, Spain
ISSN: 20472501





Health Information Science and Systems
Editorial
SPRINGER, ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES, USA
Tipo de documento: Article
Volumen: 13 Número: 1
Páginas:
WOS Id: 001596223200001
ID de PubMed: 41127713
imagen Green Accepted

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