Diagnosis and Therapy of Soft Tissue Sarcomas: Spanish Group for Research in Sarcomas (GEIS) Guidelines
Por:
Vaz-Salgado, MA, Valverde-Morales, C, Alvarez, R, Asencio, JM, Collado, E, de Alava, E, Beveridge, RD, Gómez-Mateo, MC, Alegria, IG, Marquina, G, Broto, JM, Martínez-Trufero, J, Narváez, JA, Redondo, A, Sebio, A, Verges, R, Viñals, JM, del Muro, XG
Publicada:
29 sep 2025
Resumen:
Soft tissue sarcomas (STSs) are a rare and highly heterogeneous group of tumours originating from mesenchymal cells, characterized by significant clinical and biological diversity. Due to this complexity, STSs present considerable challenges in both diagnosis and treatment, requiring an expert, multidisciplinary, and coordinated approach. To address these challenges, a multidisciplinary team of experts from the Spanish Group for Research in Sarcomas (GEIS) has developed a comprehensive, evidence-based consensus guideline that incorporates the latest advancements in biology, imaging techniques, and treatment options. The primary objective of this guideline is to provide clear and practical, up-to-date recommendations addressing the key questions that arise in the management of STSs. This approach aims to support therapeutic decision-making, enhance overall patient management, and ultimately improve clinical outcomes for patients affected by STSs. Key recommendations include the use of MRI as the preferred imaging modality prior to biopsy and ensuring that all patients are referred to specialised sarcoma centres with a multidisciplinary team for diagnosis and treatment.
Filiaciones:
Vaz-Salgado, MA:
Hosp Univ Ramon y Cajal Irycis, Med Oncol Dept, Madrid 28034, Spain
Valverde-Morales, C:
Hosp Univ Vall DHebron, Med Oncol Dept, Barcelona 08035, Spain
Alvarez, R:
Hosp Gen Univ Gregorio Maranon, Med Oncol Dept, Madrid 28007, Spain
Asencio, JM:
Hosp Gen Univ Gregorio Maranon, Gen Surg Dept, CSUR Sarcoma & Mesenchymal Tumors, Madrid 28007, Spain
Collado, E:
Hosp Clin Valencia, Radiat Oncol Dept, Valencia 46010, Spain
de Alava, E:
Univ Seville, Virgen del Rocio Univ Hosp, Inst Biomed Sevilla IBiS, CSIC,CIBERONC, Seville 41013, Spain
Univ Seville, Sch Med, Dept Normal & Pathol Cytol & Histol, Seville 41004, Spain
Beveridge, RD:
Hosp Univ & Politecn Fe Valencia, Med Oncol Dept, Valencia 46026, Spain
Gómez-Mateo, MC:
Hosp Univ Miguel Servet, Pathol Dept, Zaragoza 50009, Spain
Alegria, IG:
Hosp Santa Creu & Sant Pau, Orthoaped & Traumatol Dept, Orthopaed Oncol Unit, Barcelona 08041, Spain
Marquina, G:
Hosp Clin San Carlos, Med Oncol Dept, Sch Med, UCM,IdISSC,EURACAN Referral Ctr, Madrid 28040, Spain
Broto, JM:
Hosp Univ Fdn Jimenez Diaz, Med Oncol Dept, Madrid 28040, Spain
Gen Villalba, Madrid 28400, Spain
Inst Invest Sanitaria Fdn Jimenez Diaz, Madrid 28003, Spain
Martínez-Trufero, J:
Hosp Univ Miguel Servet, Med Oncol Dept, Zaragoza 50009, Spain
Narváez, JA:
Hosp Univ Bellvitge, Musculoskeletal Radiol, Barcelona 08907, Spain
Redondo, A:
Hosp Univ La Paz IdiPAZ, Med Oncol Dept, Madrid 28046, Spain
Sebio, A:
Hosp Santa Creu& St Pau, Med Oncol Dept, Barcelona 08041, Spain
Verges, R:
Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Radiotherapy Dept, Barcelona 08193, Spain
Viñals, JM:
Hosp Bellvitge Princeps Espanya, Plast Surg Dept, Lhospitalet De Llobregat 08908, Barcelona, Spain
del Muro, XG:
Univ Barcelona, Inst Catalan Oncol, Med Oncol Dept, Sarcoma Multidisciplinary Unit, Barcelona 08007, Spain
Green Accepted, Green Submitted, gold
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