Reliability, validity, and diagnostic accuracy of Parkinson's Disease-Cognitive Rating Scale in Iranian patients with idiopathic Parkinson's disease
Por:
Asl, AM, Mehdizadeh, M, Kulisevsky, J, Sabet, A, Sharabiani, PTA, Mehdizadeh, H, Ashayeri, H, Taghizadeh, G
Publicada:
8 may 2022
Ahead of Print:
1 sep 2020
Resumen:
Purpose To investigate the reliability and validity of Parkinson's Disease-Cognitive Rating Scale (PD-CRS) in Iranian patients with idiopathic PD. Methods One hundred and eighty patients with PD and 60 age-, gender-, and educational level-matched healthy individuals participated in this study. Inter-rater and test-retest reliability of the Persian version of PD-CRS was investigated in 80 patients with PD. To evaluate the construct validity of the PD-CRS, its correlation with the Scales for Outcomes in Parkinson's disease-Cognition (SCOPA-Cog), Mini-Mental State Examination, Montreal Cognitive Assessment, Clock Drawing Test, Unified Parkinson's Disease Rating Scale-Section I, and Quick Dementia Rating System was assessed. To assess the diagnostic accuracy of the PD-CRS, patients with PD were classified as groups with normal cognitive function, mild cognitive impairment (MCI), and dementia using the Clinical Dementia Rating. Results Test-retest and inter-rater reliability (ICC > 0.90), as well as internal consistency (alpha = 0.94) of the Persian version of PD-CRS, were excellent. A high positive correlation was found between the PD-CRS and SCOPA-Cog. A cut-off point of <= 79 (sensitivity 98.15% and specificity 98.04%) and <= 62 (sensitivity 100%, and specificity 100%) on the PD-CRS total score was obtained for detecting MCI and dementia in PD patients, respectively. Conclusions The results of this study showed that the Persian version of PD-CRS is a reliable and valid measure with high sensitivity and specificity to identify MCI and dementia in patients with PD.
Filiaciones:
Asl, AM:
Iran Univ Med Sci, Sch Rehabil Sci, Dept Occupat Therapy, Tehran, Iran
Univ Salamanca, Inst Biomed Res Salamanca, Neurosci Res Unit, Salamanca, Spain
Mehdizadeh, M:
Iran Univ Med Sci, Cellular & Mol Res Ctr, Tehran, Iran
Iran Univ Med Sci, Fac Adv Technol Med, Dept Neurosci, Tehran, Iran
Kulisevsky, J:
Hosp Santa Creu & Sant Pau, Neurol Dept, Movement Disorders Unit, Barcelona, Spain
Univ Autonoma Barcelona UAB, Inst Invest Biomed St Pau IIB St Pau, Ctr Invest Red Enfermedades Neurodegenerat CIBERN, Barcelona, Spain
Sabet, A:
Iran Univ Med Sci, Sch Rehabil Sci, Dept Occupat Therapy, Tehran, Iran
Sharabiani, PTA:
Iran Univ Med Sci, Shafa Yahyaeian Hosp, Dept Occupat Therapy, Tehran, Iran
Mehdizadeh, H:
Univ Tehran Med Sci, Sch Adv Technol Med, Dept Neurosci, Tehran, Iran
Ashayeri, H:
Iran Univ Med Sci, Sch Rehabil Sci, Dept Basic Sci, Rehabil Res Ctr, Tehran, Iran
Taghizadeh, G:
Iran Univ Med Sci, Sch Rehabil Sci, Dept Occupat Therapy, Rehabil Res Ctr, Shahnazari St,Mirdamad Blvd, Tehran, Iran
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