A Study of the Relationship Between Objective Tests to Diagnose Erectile Dysfunction and Markers of Cardiovascular Disease
Por:
Ponce, MD, Schwieters, CFQ, Meziere, J, Curbelo, JRS, Carratala, GA, Troka, E, Arnau, LB, Castañé, ER, Barcina, MJM, Rajmil, O
Publicada:
1 nov 2024
Resumen:
Background: Erectile dysfunction (ED) can stem from various organic and functional causes but is often linked to vascular health and cardiovascular disease. Limited data exist on how cardiovascular disease markers correlate with objective ED tests like the Nocturnal Penile Tumescence and Rigidity (NPTR) test and Penile Color Doppler Ultrasound (PCDU). Methods: A prospective observational study was performed, and 58 men with ED were assessed using the International Index of Erectile Function-15 (IIEF-15), NPTR test, and PCDU. Peripheral vascular health was evaluated through carotid intima-media thickness (cIMT) and brachial flow-mediated dilation (FMD). Results: Out of the participants, 44 had normal NPTR results, while 14 had abnormal results. The group with abnormal NPTR results was significantly older and had higher rates of hypertension and diabetes. Although the IIEF-15 scores were similar between the two groups, those with abnormal NPTR results had a lower peak systolic velocity (PSV) and a higher prevalence of impaired PSV. Correlations between the IIEF, NPTR, PCDU, and peripheral vascular markers lost significance after the age adjustment. Conclusions: This study suggests that abnormal NPTR results, combined with cardiovascular risk factors, may signal vascular ED and generalized vasculopathy, highlighting the need for cardiovascular assessment. An accurate ED diagnosis should integrate clinical evaluation with multiple tests while considering aging as a key risk factor.
Filiaciones:
Ponce, MD:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Schwieters, CFQ:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Meziere, J:
San Luigi Gonzaga Hosp, I-10043 Orbassano, Italy
Curbelo, JRS:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Carratala, GA:
Hosp Prov Castellon Plana, Castellon De La Plana 12002, Spain
Troka, E:
Univ Padua, Fac Med & Chirurg, I-35127 Padua, Italy
Arnau, LB:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Castañé, ER:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Barcina, MJM:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
Rajmil, O:
Univ Autonoma Barcelona, Fdn Puigvert, Inst Invest Biomed St Pau IIB St Pau, Barcelona 08041, Spain
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