Acute Myeloid Leukemia as a Trigger for Hemolytic-Uremic Syndrome
Por:
El Bachouti, J, Domínguez-Guasch, A, Arce, Y, Oñate, G, Marco, H, Diaz, M, Guirado, L, Torra, R, Barros, X
Publicada:
1 nov 2024
Resumen:
Acute myeloid leukemia (AML) has not been identified as a cause of secondary hemolytic-uremic syndrome (HUS). This case report describes a woman who developed severe HUS at the time of AML diagnosis and responded favorably to initial treatment with eculizumab, which stabilized her condition and allowed for treatment of the AML. After one year, with stable renal function and genetic studies reported as normal, eculizumab was successfully discontinued. The prompt use of eculizumab was critical to the patient's survival and improvement in renal function, highlighting the efficacy of early eculizumab treatment in secondary HUS.
Filiaciones:
El Bachouti, J:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Domínguez-Guasch, A:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Arce, Y:
Fdn Puigvert, Dept Pathol, Barcelona 08025, Spain
Oñate, G:
Hosp Santa Creu i Sant Pau, Dept Hematol, Barcelona 08025, Spain
Marco, H:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Diaz, M:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Guirado, L:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Torra, R:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
Barros, X:
Fdn Puigvert, Dept Nephrol, Barcelona 08025, Spain
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