New therapeutic era for migraine attacks with recently approved monoclonal antibodies, ditans and gepants
Por:
Mínguez-Olaondo, A, López-Bravo, A, Quintas, S, Nieves-Castellanos, C, Layos-Romero, A, Belvís, R, Irimia, P, Díaz-Insa, S
Publicada:
16 ene 2024
Resumen:
Treatment of migraine attacks is advised in all patients, using non-steroidal anti-inflammatory drugs when the pain is mild and triptans when the pain intensity is moderate-severe. However, the effectiveness of these drugs is moderate, a high percentage of patients have side effects, and triptans are contraindicated in people with a history of stroke, ischaemic heart disease or poorly controlled hypertension. Hence, there is an urgent need for new therapeutic alternatives. In recent years, new drugs for migraine attacks have become available, most notably ditans (lasmiditan) and gepants (ubrogepant and rimegepant). Furthermore, eptinezumab, which has been approved for the preventive treatment of migraine in adults, has also been used for migraine attacks. This manuscript reviews the efficacy and safety results of the new drugs for migraines that will soon be on the market.
Filiaciones:
Mínguez-Olaondo, A:
Hosp Univ Donostia Osakidetza, Serv Neurol, Begiristain Doktorea Pasealekua S-N, E-20014 San Sebastian, Spain
Univ Deusto, Athenea Neuroclin, Bilbao, Spain
Univ Deusto, Area Neurociencias, Inst Invest Sanitaria Biogipuzkoa, Bilbao, Spain
Univ Deusto, Fac Ciencias Salud, Bilbao, Spain
López-Bravo, A:
Inst Invest Sanitaria Aragon, Zaragoza, Spain
Hosp Reina Sofia, Serv Neurol, Tudela, Spain
Quintas, S:
Hosp Univ La Princesa, Serv Neurol, Madrid, Spain
Nieves-Castellanos, C:
Hosp Univ Politecn La Fe, Serv Neurol, Valencia, Spain
Inst Invest Sanitaria La Fe, Linea Invest Cefaleas, Valencia, Spain
Layos-Romero, A:
Hosp Univ Albacete, Serv Neurol, Albacete, Spain
Belvís, R:
Hosp Santa Creu & Sant Pau, Serv Neurol, Barcelona, Spain
Irimia, P:
Univ Navarra, Dept Neurol Clin, Pamplona, Spain
Díaz-Insa, S:
Hosp Univ Politecn La Fe, Serv Neurol, Valencia, Spain
Inst Invest Sanitaria La Fe, Linea Invest Cefaleas, Valencia, Spain
Green Published
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