Medical help-seeking intentions among patients with early Alzheimer's disease
Por:
Villarejo-Galende, A, García-Arcelay, E, Piñol-Ripoll, G, del Olmo-Rodríguez, A, Viñuela, F, Boada, M, Franco-Macías, E, de la Peña, AI, Riverol, M, Puig-Pijoan, A, Abizanda-Soler, P, Arroyo, R, Baquero-Toledo, M, Feria-Vilar, I, Balasa, M, Berbel, A, Rodríguez-Rodríguez, E, Vieira-Campos, A, Garcia-Ribas, G, Rodrigo-Herrero, S, Lleó, A, Maurino, J
Publicada:
19 dic 2023
Resumen:
BackgroundLimited information is available on the active process of seeking medical help in patients with Alzheimer's disease (AD) at early stages. The aim of this study was to assess the phenomenon of medical help-seeking in early AD and to identify associated factors.MethodsA multicenter, non-interventional study was conducted including patients of 50-90 years of age with prodromal or mild AD (National Institute on Aging/Alzheimer's Association criteria), a Mini-Mental State Examination (MMSE) score >= 22, and a Clinical Dementia Rating-Global score (CDR-GS) of 0.5-1.0. A multivariate logistic regression analysis was conducted.ResultsA total of 149 patients were included. Mean age (SD) was 72.3 (7.0) years, 50.3% were female, and 87.2% had a CDR-GS score of 0.5. Mean disease duration was 1.4 (1.8) years. Ninety-four (63.1%) patients sought medical help, mostly from neurologists. Patients with help-seeking intentions were mostly female (60.6%) with a CDR-GS score of 0.5 (91.5%) and had a greater awareness of diagnosis, poorer quality of life, more depressive symptoms, and a more severe perception of their condition than their counterparts. Lack of help-seeking intentions was associated with male sex (p = 0.003), fewer years of education (p = 0.005), a low awareness of diagnosis (p = 0.005), and a low emotional consequence of the condition (p = 0.016).ConclusionUnderstanding the phenomenon of active medical help-seeking may facilitate the design of specific strategies to improve the detection of cognitive impairment, especially in patients with a lower level of educational attainment and poor awareness of their condition.
Filiaciones:
Villarejo-Galende, A:
Hosp Univ 12 Octubre, Univ Complutense Madrid, Dept Neurol, Inst Invest Imas12, Madrid, Spain
García-Arcelay, E:
Roche Farma, Med Dept, Madrid, Spain
Piñol-Ripoll, G:
Hosp Univ Santa Maria Lleida, Cognit Disorders Unit, Lleida, Spain
del Olmo-Rodríguez, A:
Hosp Univ Dr Peset, Dept Neurol, Hosp Univ Dr, Valencia, Spain
Viñuela, F:
Hosp Univ Virgen Macarena, Cognit Impairment Unit, Seville, Spain
Boada, M:
Ace Alzheimer Ctr Barcelona, Barcelona, Spain
Franco-Macías, E:
Hosp Univ Virgen Rocio, Dept Neurol, Dementia Unit, Seville, Spain
de la Peña, AI:
Policlin Guipuzcoa, San Sebastian, Spain
Riverol, M:
Univ Navarra, Clin Univ Navarra, Dept Neurol, Pamplona, Spain
Puig-Pijoan, A:
Hosp Mar, Dept Neurol, Cognit Impairment & Movement Disorders Unit, Barcelona, Spain
Abizanda-Soler, P:
Complejo Hosp Univ Albacete, Dept Geriatr, Albacete, Spain
Arroyo, R:
Hosp Univ Quironsalud, Dept Neurol, Madrid, Spain
Baquero-Toledo, M:
Hosp Univ, Dept Neurol, Grp Invest Malaltia Alzheimer, Valencia, Spain
Politecn La Fe, Valencia, Spain
Feria-Vilar, I:
Complejo Hosp Univ Albacete, Dept Neurol, Albacete, Spain
Balasa, M:
Hosp Clin Barcelona, Unit Alzheimers Dis & Other Cognit Disorders, Barcelona, Spain
Berbel, A:
Hosp Cent Cruz Roja, Dept Neurol, Madrid, Spain
Rodríguez-Rodríguez, E:
Univ Cantabria, Hosp Univ Marques Valdecilla, Dept Neurol, IDIVAL, Santander, Spain
Vieira-Campos, A:
Hosp Univ Princesa, Dept Neurol, Madrid, Spain
Garcia-Ribas, G:
Hosp Univ Ramon y Cajal, Dept Neurol, Madrid, Spain
Rodrigo-Herrero, S:
Hosp Univ Juan Ramon Jimenez, Dept Neurol, Memory Unit, Huelva, Spain
Lleó, A:
Hosp Santa Creu & Sant Pau, Dept Neurol, Barcelona, Spain
Maurino, J:
Roche Farma, Med Dept, Madrid, Spain
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