Programa de optimización de antibioterapia en infección urinaria por cepas multirresistentes en el servicio de urgencias.


Por: Ruiz-Ramos J, Herrera-Mateo S, Rivera-Martínez MA, Monje-López AE, Hernández-Ontiveros H, Pereia-Batista CS, Martinez-Ysasis YM, Puig-Campmany M

Publicada: 1 oct 2023 Ahead of Print: 17 jul 2023
Resumen:
OBJECTIVE: Urinary tract infections (UTI) are a frequent reason for attendance at emergency department (ED). The present study evaluates the impact of a multidisciplinary program for the optimization of antibiotic therapy in patients with UTI caused by multi-drug resistant bacteria treated from the hospital ED. METHODS: Descriptive study of the implementation of a program in which emergency, microbiology and pharmacy departments participated. Antibiotic treatment of the patients who consulted the ED with positive urine cultures caused by multidrug-resistant bacteria was reviewed upon discharge. In those patients with inappropriate treatment, doctors and/or pharmacists of the next level of healthcare or patients in the case of home discharge were contacted. The impact of the program was evaluated based on new visits to the ED at 30 days after discharge, compared with the results obtained from the usual practice three months prior the intervention. RESULTS: During the first year, 2,474 urine cultures of patients with UTI were reviewed, 533 (21.7%) were caused by multidrug-resistant bacteria. Empirical treatment was inappropriate in 287 (53.4%), making treatment modifications in 243 of them. 73 (19.3%) patients returned to the ED 30 days after discharge, being lower than the results obtained in the three months prior intervention (27.9%; p=0.031), without significant differences in new visits associated with UTI. CONCLUSIONS: The implementation of a multidisciplinary program focused on multidrug resistant UTI at discharge form ED correct antibiotic therapy in a large number of patients, being a potentially tool to reduce the number of new ED visits.

Filiaciones:
Ruiz-Ramos J:
 Servicio de Farmacia. Hospital Santa Creu i Sant Pau. Barcelona, Spain.

Herrera-Mateo S:
 Servicio de Urgencias. Hospital Santa Creu i Sant Pau. Barcelona, España

Rivera-Martínez MA:
 Servicio de Microbiología. Hospital Santa Creu i Sant Pau. Barcelona, España

Monje-López AE:
 Servicio de Farmacia. Hospital Santa Creu i Sant Pau. Barcelona, Spain.

Hernández-Ontiveros H:
 Servicio de Urgencias. Hospital Santa Creu i Sant Pau. Barcelona, España

Pereia-Batista CS:
 Servicio de Microbiología. Hospital Santa Creu i Sant Pau. Barcelona, España

Martinez-Ysasis YM:
 Servicio de Microbiología. Hospital Santa Creu i Sant Pau. Barcelona, España

Puig-Campmany M:
 Servicio de Urgencias. Hospital Santa Creu i Sant Pau. Barcelona, España
ISSN: 02143429





Revista Espanola de Quimioterapia
Editorial
SOCIEDAD ESPANOLA QUIMIOTERAPIA, UNIV COMPLUTENSE MADRID, MICROBIOLOGY DEPT, SCHOOL MEDICINE, AVDA COMPLUTENSE S/N, MADRID, 28040, SPAIN, España
Tipo de documento: Article
Volumen: 36 Número: 5
Páginas: 486-491
WOS Id: 001113652400005
ID de PubMed: 37458335
imagen gold, Green Published, All Open Access; Gold

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