Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR)


Por: Giulioni C., Brocca C., Gauhar V., Somani B.K., Chew B.H., Traxer O., Emiliani E., Innoue T., Sarica K., Gadzhiev N., Tanidir Y., Teoh J.Y.-C., Galosi A.B., Castellani D.

Publicada: 8 sep 2023 Ahead of Print: 1 ene 2023
Resumen:
BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS: Data from 12 centers were retrospectively reviewed. INCLUSION CRITERIA: = 75 years, renal stones only, normal renal anatomy. Patients were divided into three groups; Group 1: patients aged 75-79 years; Group 2: age 80-84 years; Group 3: age = 85 years. Multivariable logistic regression analyses were performed to assess factors associated with perioperative complications, sepsis, and RFs. RESULTS: 366 patients were included. There were 189 patients in Group 1, 113 in Group 2, and 64 in Group 3. There was no difference between groups regarding stone features and total surgical time. Median length of stay was significantly longer in Group 3 (6.0 days, vs 2.0 days in Group 2 vs 2.5 days in Group 1, p = 0.043). There was no significant difference in postoperative complications and RFs between the groups. At multivariable logistic regression analysis, female gender (OR 2.82) and maximum stone diameter (OR 1.14) were associated with higher odds of sepsis, while surgical time (OR 1.12) and the use of a reusable ureteroscope (OR 6.51) with overall complications. Stone size (OR 1.23) was associated with higher odds of RFs. CONCLUSION: RIRS showed safety and efficacy for kidney stones in elderly patients. Surgical time should be kept as short as possible to avoid higher odds of postoperative complications, particularly in females.

Filiaciones:
Giulioni C.:
 Urology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, Ancona, 60126, Italy

Brocca C.:
 Urology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, Ancona, 60126, Italy

Gauhar V.:
 Department of Urology, Ng Teng Fong General Hospital, Jurong East, Singapore

Somani B.K.:
 Department of Urology, University Hospitals Southampton, NHS Trust, Southampton, United Kingdom

Chew B.H.:
 Department of Urology, University of British Columbia, Vancouver, Canada

Traxer O.:
 Department of Urology AP-HP, Sorbonne University, Tenon Hospital, Paris, France

Emiliani E.:
 Department of Urology, Fundación Puigvert, Universidad Autónoma de Barcelona, Barcelona, Spain

Innoue T.:
 Department of Urology and Stone Center, Hara Genitourinary Hospital, Hyogo, Kobe, Japan

Sarica K.:
 Department of Urology, Biruni University Medical School, Istanbul, Turkey

Gadzhiev N.:
 Endourology department, Saint-Petersburg State Medical University, Saint-Petersburg, Russian Federation

Tanidir Y.:
 Department of Urology, Marmara University School of Medicine, Istanbul, Turkey

Teoh J.Y.-C.:
 Department of Surgery, Faculty of Medicine, S.H. Ho Urology Centre, The Chinese University of Hong Kong, Hong Kong

Galosi A.B.:
 Urology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, Ancona, 60126, Italy

Castellani D.:
 Urology Unit, Azienda Ospedaliero-Universitaria Delle Marche, Università Politecnica Delle Marche, Via Conca 71, Ancona, 60126, Italy
ISSN: 15940667
Editorial
SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA, Italia
Tipo de documento: Article
Volumen: 35 Número: 11
Páginas: 2711-2719
WOS Id: 001061565500003
ID de PubMed: 37682489
imagen hybrid, All Open Access; Hybrid Gold

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