Changes in Principal Caregiver Mood Affects the Mood of the Parkinson's Disease Patient: The Vicious Cycle of Illness


Por: Santos-García D., Fonticoba, TD, Bartolome, CC, Painceiras, MJF, Iniguez-Alvarado, MC, Diaz, IG, Jesús S., Buongiorno M.T., Planellas L., Cosgaya M., Caldentey, JG, Caballol N., Legarda I., Vara, JH, Cabo I., Manzanares, LL, Aramburu, IG, Rivera, MAA, Mayordomo, VG, Nogueira V., Puente V., Garcia-Soto, JD, Borrué C., Vila, BS, Sauco, MA, Vela L., Escalante S., Cubo E., Padilla, FC, Castrillo, JCM, Alonso, PS, Losada, MGA, Ariztegui, NL, Gastón I., Kulisevsky J., Gonzalez, MM, Seijo M., Martinez, JR, Valero C., Kurtis M., Ardura, JG, Redondo, RA, Ordás C., Diaz, LML, McAfee D., Martinez-Martin P., Mir P.

Publicada: 1 ene 2023
Resumen:
Background: Although many studies have analyzed what factors contribute to caregiver burden in Parkinson's disease (PD), there is currently no knowledge about how the status of the caregiver could impact the patient. Objective: The aim of this study was to analyze how the change in the caregiver's status influences PD patients. Methods: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers in Spain from the COPPADIS cohort were included in the study (V0). They were evaluated again at 2-year follow-up (V2). Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), and EUROHIS-QOL 8-item index (EUROHIS-QOL8) at V0 and V2. Multivariate models were used to analyze the impact of the change from V0 to V2 ( similar to) on the caregiver's status over the change in the patient's status. Results: similar to BDI-II and similar to EUROHIS-QOL8 in the caregiver predicted similar to BDI-II (similar to = 0.32; p < 0.0001; R2 = 0.71) and similar to EUROHIS-QOL8 (similar to = 0.39; p < 0.0001; R2 = 0.68) in the patient, respectively. Variables related to the caregiver were not associated with changes in the patient ' s health-related QoL ( similar to PDQ-39 [39-item Parkinson's disease Questionnaire]) or autonomy for activities of daily-living ( similar to ADLS [Schwab & England Activities of Daily Living Scale]). Conclusion: The change in the caregiver's mood and global QoL was associated with the change in the patient's mood and global QoL, respectively, independently of other variables of the disease influencing both patient ' s aspects. Based on this finding, it could be of great importance to detect depression in the principal caregiver of a patient and act on it as earlier as possible.

Filiaciones:
Santos-García D.:
 CHUAC, La Coruna, Spain

Fonticoba, TD:
 CHUF, La Coruna, Spain

Bartolome, CC:
 CHUAC, La Coruna, Spain

Painceiras, MJF:
 CHUAC, La Coruna, Spain

Iniguez-Alvarado, MC:
 CHUAC, La Coruna, Spain

Diaz, IG:
 CHUAC, La Coruna, Spain

Jesús S.:
 Univ Seville, Inst Biomed Sevilla, Serv Neurol & Neurofisiol Clin,CSIC, Unidad Trastornos Movimiento,Hosp Univ Virgen Roc, Seville, Spain

 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

Buongiorno M.T.:
 Hosp Univ Mutua Terrassa, Barcelona, Spain

Planellas L.:
 Clin Pilar, Barcelona, Spain

Cosgaya M.:
 Hosp Clin Barcelona, Barcelona, Spain

Caldentey, JG:
 Ctr Neurol Oms 42, Palma de Mallorca, Spain

Caballol N.:
 Hosp Moises Broggi, Consorci Sanitari Integral, Barcelona, Spain

Legarda I.:
 Hosp Univ Son Espases, Palma De Mallorca, Spain

Vara, JH:
 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

 Hosp Univ Vall dHebron, Barcelona, Spain

Cabo I.:
 Complejo Hosp Univ Pontevedra CHOP, Pontevedra, Spain

Manzanares, LL:
 Hosp Univ La Princesa, Madrid, Spain

Aramburu, IG:
 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

 Hosp Univ Marques Valdecilla, Santander, Spain

Rivera, MAA:
 Hosp Gen LHosp, Consorci Sanitari Integral, Barcelona, Spain

Mayordomo, VG:
 Hosp Univ Clin San Carlos, Madrid, Spain

Nogueira V.:
 Hosp Costa, Lugo, Spain

Puente V.:
 Hosp Mar, Barcelona, Spain

Garcia-Soto, JD:
 Hosp Univ Virgen Macarena, Seville, Spain

Borrué C.:
 Hosp Infanta Sofia, Madrid, Spain

Vila, BS:
 Inst Assistencia Sanitaria IAS, Inst Catala Salut, Girona, Spain

Sauco, MA:
 Hosp Gen Univ Elche, Elche, Spain

Vela L.:
 Fdn Hosp Alcorcon, Madrid, Spain

Escalante S.:
 Hosp Tortosa Verge Cinta HTVC, Tarragona, Spain

Cubo E.:
 Complejo Asistencial Univ Burgos, Burgos, Spain

Padilla, FC:
 Hosp Univ Canarias, San Cristobal De Laguna, Santa Cruz De T, Spain

Castrillo, JCM:
 Hosp Univ Ramon y Cajal, IRYCIS, Madrid, Spain

Alonso, PS:
 Hosp Univ Puerta Hierro, Madrid, Spain

Losada, MGA:
 Complejo Hosp Univ Vigo CHUVI, Hosp Alvaro Cunqueiro, Vigo, Spain

Ariztegui, NL:
 Complejo Hosp Toledo, Toledo, Spain

Gastón I.:
 Complejo Hosp Navarra, Pamplona, Spain

Kulisevsky J.:
 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

 Hosp Santa Creu & Sant Pau, Barcelona, Spain

Gonzalez, MM:
 Hosp Univ Cent Asturias, Oviedo, Spain

Seijo M.:
 Complejo Hosp Univ Pontevedra CHOP, Pontevedra, Spain

Martinez, JR:
 Hosp Univ Donostia, San Sebastian, Spain

Valero C.:
 Hosp Arnau Vilanova, Valencia, Spain

Kurtis M.:
 Hosp Ruber Int, Madrid, Spain

Ardura, JG:
 Hosp Cabuenes, Gijon, Spain

Redondo, RA:
 Univ Lucus Augusti HULA, Lugo, Spain

Ordás C.:
 Hosp Rey Juan Carlos, Madrid, Spain

Diaz, LML:
 Complejo Hosp Univ Vigo CHUVI, Hosp Alvaro Cunqueiro, Vigo, Spain

McAfee D.:
 Univ Maryland, Sch Med, Baltimore, MD 21201 USA

Martinez-Martin P.:
 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain

Mir P.:
 Univ Seville, Inst Biomed Sevilla, Serv Neurol & Neurofisiol Clin,CSIC, Unidad Trastornos Movimiento,Hosp Univ Virgen Roc, Seville, Spain

 CIBERNED Ctr Invest Biomed Red Enfermedades Neuro, Madrid, Spain
ISSN: 18777171
Editorial
IOS PRESS, NIEUWE HEMWEG 6B, 1013 BG AMSTERDAM, NETHERLANDS, Países Bajos
Tipo de documento: Article
Volumen: 13 Número: 2
Páginas: 219-231
WOS Id: 000950452000008
ID de PubMed: 36683517
imagen Green Published, hybrid, All Open Access, Bronze, Green

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