Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
Por:
Guerrero-Vadillo, M, Penuelas, M, Dominguez, A, Godoy, P, Gomez-Barroso, D, Soldevila, N, Izquierdo, C, Martinez, A, Torner, N, Avellon, A, Rius, C, Varela, C
Publicada:
1 dic 2022
Resumen:
The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016-2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space-time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15-44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space-time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging.
Filiaciones:
Guerrero-Vadillo, M:
Univ Nacl Educ Distancia, Doctorate Programme Biomed Sci & Publ Hlth, Madrid 28015, Spain
Inst Salud Carlos III, Natl Ctr Epidemiol, Madrid 28029, Spain
Penuelas, M:
Inst Salud Carlos III, Natl Ctr Epidemiol, Madrid 28029, Spain
Dominguez, A:
Univ Barcelona UB, Dept Med, Barcelona 08036, Spain
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Godoy, P:
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Univ Lleida, Dept Med, Inst Recerca Biomed Lleida IRBLLeida, Lleida 25008, Spain
Gomez-Barroso, D:
Inst Salud Carlos III, Natl Ctr Epidemiol, Madrid 28029, Spain
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Soldevila, N:
Univ Barcelona UB, Dept Med, Barcelona 08036, Spain
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Izquierdo, C:
Agencia Salut Publ Catalunya, Barcelona 08005, Spain
Martinez, A:
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Agencia Salut Publ Catalunya, Barcelona 08005, Spain
Torner, N:
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Avellon, A:
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Inst Salud Carlos III, Natl Ctr Microbiol, Hepatitis Unit, Majadahonda 28222, Spain
Rius, C:
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Agencia Salut Publ Barcelona, Barcelona 08023, Spain
Varela, C:
Inst Salud Carlos III, Natl Ctr Epidemiol, Madrid 28029, Spain
Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid 28029, Spain
Green Published, gold
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