Whole-genome sequencing reveals host factors underlying critical COVID-19

Por: Pairo-Castineira E., Rawlik K., Russell C.D., Malinauskas T., Wu Y., Millar J., Shen X., Elliott K.S., Griffiths F., Oosthuyzen W., Morrice K., Keating S., Wang B., Klaric L., Zechner M., Parkinson N., Siddiq A., Goddard P., Donovan S., Maslove D., Nichol A., Semple M.G., Zainy T., Maleady-Crowe F., Todd L., Salehi S., Knight J., Elgar G., Patch C., Bentley D., Kingsley C., Justice A., Oetjens M., Rader D.J., Fowler T.A., Shankar-Hari M., Summers C., Hinds C., Horby P., Ling L., McAuley D., Montgomery H., Openshaw P.J.M., Elliott P., Walsh T., Shelton J.F., Shastri A.J., Ye C., Weldon C.H., Filshtein-Sonmez T., Coker D., Symons A., Esparza-Gordillo J., Aslibekyan S., Auton A., Pathak G.A., Karjalainen J., Stevens C., Andrews S.J., Kanai M., Cordioli M., Polimanti R., Pirinen M., Harerimana N., Veerapen K., Wolford B., Nguyen H., Solomonson M., Liao R.G., Chwialkowska K., Trankiem A., Balaconis M.K., Hayward C., Richmond A., Campbell A., Morris M., Fawns-Ritchie C., Glessner J.T., Shaw D.M., Chang X., Polikowski H., Petty L.E., Chen H.-H., Wanying Z., Porteous D.J., Below J., North K., McCormick J.B., Timmers P.R.H.J., Tenesa A., D’Mellow K., Kerr S.M., Niemi M.E.K., von Hohenstaufen K.A., Sobh A., Eltoukhy M.M., Yassen A.M., Hegazy M.A.F., Okasha K., Eid M.A., Moahmed H.S., Shahin D., El-Sherbiny Y.M., Elhadidy T.A., Abd Elghafar M.S., El-Jawhari J.J., Mohamed A.A.S., Elnagdy M.H., Samir A., Abdel-Aziz M., Khafaga W.T., El-Lawaty W.M., Torky M.S., El-shanshory M.R., Batini C., Lee P.H., Shrine N., Williams A.T., Tobin M.D., Guyatt A.L., John C., Packer R.J., Ali A., Free R.C., Wang X., Wain L.V., Hollox E.J., Venn L.D., Bee C.E., Adams E.L., Niavarani A., Sharififard B., Aliannejad R., Amirsavadkouhi A., Naderpour Z., Tadi H.A., Aleagha A.E., Ahmadi S., Moghaddam S.B.M., Adamsara A., Saeedi M., Abdollahi H., Hosseini A., Chariyavilaskul P., Chamnanphon M., Suttichet T.B., Shotelersuk V., Pongpanich M., Phokaew C., Chetruengchai W., Jantarabenjakul W., Putchareon O., Torvorapanit P., Puthanakit T., Suchartlikitwong P., Hirankarn N., Nilaratanakul V., Sodsai P., Brumpton B.M., Hveem K., Willer C., Zhou W., Rogne T., Solligard E., Åsvold B.O., Abedalthagafi M., Alaamery M., Alqahtani S., Barakeh D., Al Harthi F., Alsolm E., Safieh L.A., Alowayn A.M., Alqubaishi F., Al Mutairi A., Mangul S., Alshareef A., Sawaji M., Almutairi M., Aljawini N., Albesher N., Arabi Y.M., Mahmoud E.S., Khattab A.K., Halawani R.T., Alahmadey Z.Z., Albakri J.K., Felemban W.A., Suliman B.A., Hasanato R., Al-Awdah L., Alghamdi J., AlZahrani D., AlJohani S., Al-Afghani H., Alrashed M., AlDhawi N., AlBardis H., Alkwai S., Alswailm M., Almalki F., Albeladi M., Almohammed I., Barhoush E., Albader A., Massadeh S., AlMalik A., Alotaibi S., Alghamdi B., Jung J., Fawzy M.S., Lee Y., Magnus P., Trogstad L.-I.S., Helgeland Ø., Harris J.R., Mangino M., Spector T.D., Duncan E., Smieszek S.P., Przychodzen B.P., Polymeropoulos C., Polymeropoulos V., Polymeropoulos M.H., Fernandez-Cadenas I., Perez-Tur J., Llucià-Carol L., Cullell N., Muiño E., Cárcel-Márquez J., DeDiego M.L., Iglesias L.L., Planas A.M., Soriano A., Rico V., Agüero D., Bedini J.L., Lozano F., Domingo C., Robles V., Ruiz-Jaén F., Márquez L., Gomez J., Coto E., Albaiceta G.M., García-Clemente M., Dalmau D., Arranz M.J., Dietl B., Serra-Llovich A., Soler P., Colobrán R., Martín-Nalda A., Martínez A.P., Bernardo D., Rojo S., Fiz-López A., Arribas E., de la Cal-Sabater P., Segura T., González-Villa E., Serrano-Heras G., Martí-Fàbregas J., Jiménez-Xarrié E., de Felipe Mimbrera A., Masjuan J., García-Madrona S., Domínguez-Mayoral A., Villalonga J.M., Menéndez-Valladares P., Chasman D.I., Buring J.E., Ridker P.M., Franco G., Sesso H.D., Manson J.A.E., Glessner J.R., Hakonarson H., Medina-Gomez C., Uitterlinden A.G., Ikram M.A., Kristiansson K., Koskelainen S., Perola M., Donner K., Kivinen K., Palotie A., Ripatti S., Ruotsalainen S., Kaunisto M., Nakanishi T., Butler-Laporte G., Forgetta V., Morrison D.R., Ghosh B., Laurent L., Belisle A., Henry D., Abdullah T., Adeleye O., Mamlouk N., Kimchi N., Afrasiabi Z., Rezk N., Vulesevic B., Bouab M., Guzman C., Petitjean L., Tselios C., Xue X., Schurr E., Afilalo J., Afilalo M., Oliveira M., Brenner B., Lepage P., Ragoussis J., Auld D., Brassard N., Durand M., Chassé M., Kaufmann D.E., Lathrop G.M., Mooser V., Richards J.B., Li R., Adra D., Rahmouni S., Georges M., Moutschen M., Misset B., Darcis G., Guiot J., Guntz J., Azarzar S., Gofflot S., Beguin Y., Claassen S., Malaise O., Huynen P., Meuris C., Thys M., Jacques J., Léonard P., Frippiat F., Giot J.-B., Sauvage A.-S., von Frenckell C., Belhaj Y., Lambermont B., Pigazzini S., Nkambule L., Daya M., Shortt J., Rafaels N., Wicks S.J., Crooks K., Barnes K.C., Gignoux C.R., Chavan S., Laisk T., Läll K., Lepamets M., Mägi R., Esko T., Reimann E., Milani L., Alavere H., Metsalu K., Puusepp M., Metspalu A., Naaber P., Laane E., Pesukova J., Peterson P., Kisand K., Tabri J., Allos R., Hensen K., Starkopf J., Ringmets I., Tamm A., Kallaste A., Bochud P.-Y., Rivolta C., Bibert S., Quinodoz M., Kamdar D., Boillat N., Nussle S.G., Albrich W., Suh N., Neofytos D., Erard V., Voide C., de Cid R., Galván-Femenía I., Blay N., Carreras A., Cortés B., Farré X., Sumoy L., Moreno V., Mercader J.M., Guindo-Martinez M., Torrents D., Kogevinas M., Garcia-Aymerich J., Castaño-Vinyals G., Dobaño C., Renieri A., Mari F., Fallerini C., Daga S., Benetti E., Baldassarri M., Fava F., Frullanti E., Valentino F., Doddato G., Giliberti A., Tita R., Amitrano S., Bruttini M., Croci S., Meloni I., Mencarelli M.A., Rizzo C.L., Pinto A.M., Beligni G., Tommasi A., Di Sarno L., Palmieri M., Carriero M.L., Alaverdian D., Busani S., Bruno R., Vecchia M., Belli M.A., Picchiotti N., Sanarico M., Gori M., Furini S., Mantovani S., Ludovisi S., Mondelli M.U., Castelli F., Quiros-Roldan E., Antoni M.D., Zanella I., Vaghi M., Rusconi S., Siano M., Montagnani F., Emiliozzi A., Fabbiani M., Rossetti B., Bargagli E., Bergantini L., D’Alessandro M., Cameli P., Bennett D., Anedda F., Marcantonio S., Scolletta S., Franchi F., Mazzei M.A., Guerrini S., Conticini E., Cantarini L., Frediani B., Tacconi D., Spertilli C., Feri M., Donati A., Scala R., Guidelli L., Spargi G., Corridi M., Nencioni C., Croci L., Bandini M., Caldarelli G.P., Piacentini P., Desanctis E., Cappelli S., Canaccini A., Verzuri A., Anemoli V., Ognibene A., Pancrazzi A., Lorubbio M., D’Arminio Monforte A., Miraglia F.G., Girardis M., Venturelli S., Cossarizza A., Antinori A., Vergori A., Gabrieli A., Riva A., Francisci D., Schiaroli E., Paciosi F., Scotton P.G., Andretta F., Panese S., Scaggiante R., Gatti F., Parisi S.G., Baratti S., Della Monica M., Piscopo C., Capasso M., Russo R., Andolfo I., Iolascon A., Fiorentino G., Carella M., Castori M., Merla G., Squeo G.M., Aucella F., Raggi P., Marciano C., Perna R., Bassetti M., Di Biagio A., Sanguinetti M., Masucci L., Valente S., Mandalà M., Giorli A., Salerni L., Zucchi P., Parravicini P., Menatti E., Trotta T., Giannattasio F., Coiro G., Lena F., Coviello D.A., Mussini C., Martinelli E., Mancarella S., Tavecchia L., Crotti L., Gabbi C., Rizzi M., Maggiolo F., Ripamonti D., Bachetti T., La Rovere M.T., Sarzi-Braga S., Bussotti M., Ceri S., Pinoli P., Raimondi F., Biscarini F., Stella A., Zguro K., Capitani K., Suardi C., Dei S., Parati G., Ravaglia S., Artuso R., Bottà G., Di Domenico P., Rancan I., Perrella A., Bianchi F., Romani D., Bergomi P., Catena E., Colombo R., Tanfoni M., Vincenti A., Ferri C., Grassi D., Pessina G., Tumbarello M., Di Pietro M., Sabrina R., Luchi S., Barbieri C., Acquilini D., Andreucci E., Segala F.V., Tiseo G., Falcone M., Lista M., Poscente M., De Vivo O., Petrocelli P., Guarnaccia A., Baroni S., Smith A.V., Boughton A.P., Li K.W., LeFaive J., Annis A., Justice A.E., Mirshahi T., Chittoor G., Josyula N.S., Kosmicki J.A., Ferreira M.A.R., Leader J.B., Carey D.J., Gass M.C., Horowitz J.E., Cantor M.N., Yadav A., Baras A., Abecasis G.R., van Heel D.A., Hunt K.A., Mason D., Huang Q.Q., Finer S., Trivedi B., Griffiths C.J., Martin H.C., Wright J., Trembath R.C., Soranzo N., Zhao J.H., Butterworth A.S., Danesh J., Di Angelantonio E., Franke L., Boezen M., Deelen P., Claringbould A., Lopera E., Warmerdam R., Vonk J.M., van Blokland I., Lanting P., Ori A.P.S., Zöllner S., Wang J., Beck A., Peloso G., Ho Y.-L., Sun Y.V., Huffman J.E., O’Donnell C.J., Cho K., Tsao P., Gaziano J.M., Nivard M., de Geus E., Bartels M., Jan Hottenga J., Weiss S.T., Karlson E.W., Smoller J.W., Green R.C., Feng Y.-C.A., Mercader J., Murphy S.N., Meigs J.B., Woolley A.E., Perez E.F., Rader D., Verma A., Ritchie M.D., Li B., Verma S.S., Lucas A., Bradford Y., Zeberg H., Frithiof R., Hultström M., Lipcsey M., Nkambul L., Tardif N., Rooyackers O., Grip J., Maricic T., Karczewski K.J., Atkinson E.G., Tsuo K., Baya N., Turley P., Gupta R., Callier S., Walters R.K., Palmer D.S., Sarma G., Cheng N., Lu W., Bryant S., Churchhouse C., Cusick C., Goldstein J.I., King D., Seed C., Finucane H., Martin A.R., Satterstrom F.K., Wilson D.J., Armstrong J., Rudkin J.K., Band G., Earle S.G., Lin S.-K., Arning N., Crook D.W., Wyllie D.H., O’Connell A.M., Spencer C.C.A., Koelling N., Fowler T., Kousathanas A., Pasko D., Walker S., Rendon A., Stuckey A., Odhams C.A., Rhodes D., Chan G., Arumugam P., Ball C.A., Hong E.L., Rand K., Girshick A., Guturu H., Baltzell A.H., Roberts G., Park D., Coignet M., McCurdy S., Knight S., Partha R., Rhead B., Zhang M., Berkowitz N., Gaddis M., Noto K., Ruiz L., Pavlovic M., Sloofman L.G., Charney A.W., Beckmann N.D., Schadt E.E., Jordan D.M., Thompson R.C., Gettler K., Abul-Husn N.S., Ascolillo S., Buxbaum J.D., Chaudhary K., Cho J.H., Itan Y., Kenny E.E., Belbin G.M., Sealfon S.C., Sebra R.P., Salib I., Collins B.L., Levy T., Britvan B., Keller K., Tang L., Peruggia M., Hiester L.L., Niblo K., Aksentijevich A., Labkowsky A., Karp A., Zlatopolsky M., Preuss M., Loos R.J.F., Nadkarni G.N., Do R., Hoggart C., Choi S., Underwood S.J., O’Reilly P., Huckins L.M., Zyndorf M., Daly M.J., Neale B.M., Ganna A., Fawkes A., Murphy L., Rowan K., Ponting C.P., Vitart V., Wilson J.F., Yang J., Bretherick A.D., Scott R.H., Hendry S.C., Moutsianas L., Law A., Caulfield M.J., Baillie J.K., GenOMICC co-investigators

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Publicada: 7 jul 2022 Ahead of Print: 1 mar 2022

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Filiaciones:
Pairo-Castineira E.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Rawlik K.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Russell C.D.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

 Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

Malinauskas T.:
 Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Wu Y.:
 Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia

Millar J.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Shen X.:
 Biostatistics Group, Greater Bay Area Institute of Precision Medicine (Guangzhou), Fudan University, Guangzhou, China

 Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Edinburgh, United Kingdom

Elliott K.S.:
 Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Griffiths F.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Oosthuyzen W.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Morrice K.:
 Edinburgh Clinical Research Facility, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom

Keating S.:
 Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

Wang B.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Klaric L.:
 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Zechner M.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Parkinson N.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Siddiq A.:
 Genomics England, London, United Kingdom

Goddard P.:
 Genomics England, London, United Kingdom

Donovan S.:
 Genomics England, London, United Kingdom

Maslove D.:
 Department of Critical Care Medicine, Queen’s University and Kingston Health Sciences Centre, Kingston, ON, Canada

Nichol A.:
 Clinical Research Centre at St Vincent’s University Hospital, University College Dublin, Dublin, Ireland

Semple M.G.:
 NIHR Health Protection Research Unit for Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom

 Respiratory Medicine and Institute in the Park, Alder Hey Children’s Hospital and University of Liverpool, Liverpool, United Kingdom

Zainy T.:
 Genomics England, London, United Kingdom

Maleady-Crowe F.:
 Genomics England, London, United Kingdom

Todd L.:
 Genomics England, London, United Kingdom

Salehi S.:
 Genomics England, London, United Kingdom

Knight J.:
 Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Elgar G.:
 Genomics England, London, United Kingdom

Patch C.:
 Genomics England, London, United Kingdom

Bentley D.:
 Illumina Cambridge, Great Abington, United Kingdom

Kingsley C.:
 Illumina Cambridge, Great Abington, United Kingdom

Justice A.:
 Geisinger, Danville, PA, United States

Oetjens M.:
 Geisinger, Danville, PA, United States

Rader D.J.:
 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Fowler T.A.:
 Genomics England, London, United Kingdom

 Test and Trace, the Health Security Agency, Department of Health and Social Care, London, United Kingdom

Shankar-Hari M.:
 Department of Intensive Care Medicine, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom

Summers C.:
 Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Hinds C.:
 William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

 Queen Mary University of London, London, United Kingdom

Horby P.:
 Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Ling L.:
 Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong

McAuley D.:
 Wellcome–Wolfson Institute for Experimental Medicine, Queen’s University Belfast, Belfast, United Kingdom

 Department of Intensive Care Medicine, Royal Victoria Hospital, Belfast, United Kingdom

Montgomery H.:
 UCL Centre for Human Health and Performance, London, United Kingdom

Openshaw P.J.M.:
 National Heart and Lung Institute, Imperial College London, London, United Kingdom

 Imperial College Healthcare NHS Trust: London, London, United Kingdom

Elliott P.:
 Imperial College, London, United Kingdom

Walsh T.:
 Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

Shelton J.F.:
 23andMe, Sunnyvale, CA, United States

Shastri A.J.:
 23andMe, Sunnyvale, CA, United States

Ye C.:
 23andMe, Sunnyvale, CA, United States

Weldon C.H.:
 23andMe, Sunnyvale, CA, United States

Filshtein-Sonmez T.:
 23andMe, Sunnyvale, CA, United States

Coker D.:
 23andMe, Sunnyvale, CA, United States

Symons A.:
 23andMe, Sunnyvale, CA, United States

Esparza-Gordillo J.:
 Human Genetics R&D and Target Sciences R&D, GSK Medicines Research Centre, Stevenage, United Kingdom

Aslibekyan S.:
 23andMe, Sunnyvale, CA, United States

Auton A.:
 23andMe, Sunnyvale, CA, United States

Pathak G.A.:
 Yale University, New Haven, CT, United States

Karjalainen J.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Stevens C.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Andrews S.J.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Kanai M.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Cordioli M.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Polimanti R.:
 Yale University, New Haven, CT, United States

Pirinen M.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Harerimana N.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Veerapen K.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Wolford B.:
 University of Michigan, Ann Arbor, MI, United States

Nguyen H.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Solomonson M.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Liao R.G.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Chwialkowska K.:
 Centre for Bioinformatics and Data Analysis, Medical University of Bialystok, Bialystok, Poland

Trankiem A.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Balaconis M.K.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Hayward C.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Richmond A.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Campbell A.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Morris M.:
 University of Texas Health, Houston, TX, United States

Fawns-Ritchie C.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Glessner J.T.:
 Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, United States

 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Shaw D.M.:
 Vanderbilt University Medical Center, Nashville, TN, United States

Chang X.:
 Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, United States

Polikowski H.:
 Vanderbilt University Medical Center, Nashville, TN, United States

Petty L.E.:
 Vanderbilt University Medical Center, Nashville, TN, United States

Chen H.-H.:
 Vanderbilt University Medical Center, Nashville, TN, United States

Wanying Z.:
 Vanderbilt University Medical Center, Nashville, TN, United States

Porteous D.J.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Below J.:
 Vanderbilt University Medical Center, Nashville, TN, United States

North K.:
 University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

McCormick J.B.:
 University of Texas Health, Houston, TX, United States

Timmers P.R.H.J.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Tenesa A.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

D’Mellow K.:
 Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom

Kerr S.M.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Niemi M.E.K.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

von Hohenstaufen K.A.:
 Genolier Innovation Network and Hub, Swiss Medical Network, Genolier Healthcare Campus, Genolier, Switzerland

Sobh A.:
 Department of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Eltoukhy M.M.:
 Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt

Yassen A.M.:
 Department of Anaethesia and Critical Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Hegazy M.A.F.:
 Department of Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Okasha K.:
 Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

Eid M.A.:
 Faculty of Science, Tanta University, Tanta, Egypt

Moahmed H.S.:
 Chest Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Shahin D.:
 Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

El-Sherbiny Y.M.:
 Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

 Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

Elhadidy T.A.:
 Chest Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Abd Elghafar M.S.:
 Anesthesia, Surgical Intensive Care and Pain Management Department, Faculty of Medicine, Tanta University, Tanta, Egypt

El-Jawhari J.J.:
 Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

 Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

Mohamed A.A.S.:
 Department of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt

Elnagdy M.H.:
 Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Samir A.:
 Department of Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Abdel-Aziz M.:
 Department of Tropical Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Khafaga W.T.:
 Pediatric and Neonatology, Kafr El-Zayat General Hospital, Kafr El-Zayat, Egypt

El-Lawaty W.M.:
 Chest Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Torky M.S.:
 Chest Department, Faculty of Medicine, Tanta University, Tanta, Egypt

El-shanshory M.R.:
 Pediatrics Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Batini C.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Lee P.H.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Shrine N.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Williams A.T.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Tobin M.D.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 Leicester NIHR Biomedical Research Centre, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Guyatt A.L.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

John C.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Packer R.J.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Ali A.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Free R.C.:
 Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Wang X.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Wain L.V.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Hollox E.J.:
 University of Leicester, Leicester, United Kingdom

Venn L.D.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Bee C.E.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Adams E.L.:
 Department of Health Sciences, University of Leicester, Leicester, United Kingdom

 University of Leicester, Leicester, United Kingdom

Niavarani A.:
 Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Sharififard B.:
 Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Aliannejad R.:
 Department of Pulmonology, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Amirsavadkouhi A.:
 Department of Critical Care Medicine, Noorafshar Hospital, Tehran, Iran

Naderpour Z.:
 Department of Pulmonology, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Tadi H.A.:
 Department of Emergency Intensive Care Unit, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Aleagha A.E.:
 Department of Anesthesiology, School of Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

Ahmadi S.:
 Department of Pulmonology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Moghaddam S.B.M.:
 Department of Pathology, Parseh Pathobiology and Genetics Laboratory, Tehran, Iran

Adamsara A.:
 Department of Microbiology, Health and Family Research Center, NIOC Hospital, Tehran, Iran

Saeedi M.:
 Department of Emergency Medicine, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Abdollahi H.:
 Department of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Hosseini A.:
 Department of Pathology, Faculty of Medicine, Tehran Azad University, Tehran, Iran

Chariyavilaskul P.:
 Clinical Pharmacokinetics and Pharmacogenomics Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Chamnanphon M.:
 Clinical Pharmacokinetics and Pharmacogenomics Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Department of Pathology, Faculty of Medicine, Nakornnayok, Srinakharinwirot University, Bangkok, Thailand

Suttichet T.B.:
 Clinical Pharmacokinetics and Pharmacogenomics Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Shotelersuk V.:
 Center of Excellence for Medical Genomics, Medical Genomics Cluster, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand

Pongpanich M.:
 Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

 Omics Sciences and Bioinfomatics Center, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

Phokaew C.:
 Center of Excellence for Medical Genomics, Medical Genomics Cluster, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand

 Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Chetruengchai W.:
 Center of Excellence for Medical Genomics, Medical Genomics Cluster, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Excellence Center for Genomics and Precision Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand

Jantarabenjakul W.:
 Thai Red Cross Emerging Infectious Diseases Clinical Centre, King Chulalongkorn Memorial Hospital, Bangkok, Thailand

 Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Putchareon O.:
 Thai Red Cross Emerging Infectious Diseases Clinical Centre, King Chulalongkorn Memorial Hospital, Bangkok, Thailand

 Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Torvorapanit P.:
 Thai Red Cross Emerging Infectious Diseases Clinical Centre, King Chulalongkorn Memorial Hospital, Bangkok, Thailand

 Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Puthanakit T.:
 Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Center of Excellence in Pediatric Infectious Diseases and Vaccines, Chulalongkorn University, Bangkok, Thailand

Suchartlikitwong P.:
 Center of Excellence in Pediatric Infectious Diseases and Vaccines, Chulalongkorn University, Bangkok, Thailand

 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Hirankarn N.:
 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Center of Excellence in Immunology and Immune-mediated Diseases, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Nilaratanakul V.:
 Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Healthcare-associated Infection Research Group STAR (Special Task Force for Activating Research), Chulalongkorn University, Bangkok, Thailand

Sodsai P.:
 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Immunology Division, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

 Center of Excellence in Immunology and Immune-mediated Diseases, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Brumpton B.M.:
 K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

 HUNT Research Center, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Levanger, Norway

 Clinic of Medicine, St Olav’s Hospital, Trondheim University Hospital, Trondheim, Norway

Hveem K.:
 K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

 HUNT Research Center, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Levanger, Norway

Willer C.:
 University of Michigan, Ann Arbor, MI, United States

 Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States

 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States

Zhou W.:
 Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, United States

 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Rogne T.:
 Gemini Center for Sepsis Research, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

 Department of Chronic Disease Epidemiology and Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, CT, United States

 Clinic of Anaesthesia and Intensive Care, St Olav’s Hospital, Trondheim University Hospital, Trondheim, Norway

Solligard E.:
 Gemini Center for Sepsis Research, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

 Clinic of Anaesthesia and Intensive Care, St Olav’s Hospital, Trondheim University Hospital, Trondheim, Norway

Åsvold B.O.:
 K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway

 HUNT Research Center, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Levanger, Norway

 Clinic of Medicine, St Olav’s Hospital, Trondheim University Hospital, Trondheim, Norway

Abedalthagafi M.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alaamery M.:
 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

 Saudi Human Genome Project (SHGP), King Abdulaziz City for Science and Technology (KACST), Satellite Lab at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Alqahtani S.:
 The Liver Transplant Unit, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

 The Division of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, United States

Barakeh D.:
 Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia

Al Harthi F.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alsolm E.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Safieh L.A.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alowayn A.M.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alqubaishi F.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Al Mutairi A.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Mangul S.:
 Titus Family Department of Clinical Pharmacy, USC School of Pharmacy, University of Southern California, Los Angeles, CA, United States

Alshareef A.:
 College of Applied Medical Sciences, Taibah University, Madina, Saudi Arabia

Sawaji M.:
 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Almutairi M.:
 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

 Saudi Human Genome Project (SHGP), King Abdulaziz City for Science and Technology (KACST), Satellite Lab at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Aljawini N.:
 KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Albesher N.:
 KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Arabi Y.M.:
 Ministry of the National Guard Health Affairs, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

Mahmoud E.S.:
 Ministry of the National Guard Health Affairs, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

Khattab A.K.:
 Ohud Hospital, Ministry of Health, Madinah, Saudi Arabia

Halawani R.T.:
 Ohud Hospital, Ministry of Health, Madinah, Saudi Arabia

Alahmadey Z.Z.:
 Ohud Hospital, Ministry of Health, Madinah, Saudi Arabia

Albakri J.K.:
 Ohud Hospital, Ministry of Health, Madinah, Saudi Arabia

Felemban W.A.:
 Ohud Hospital, Ministry of Health, Madinah, Saudi Arabia

Suliman B.A.:
 College of Applied Medical Sciences, Taibah University, Madina, Saudi Arabia

Hasanato R.:
 Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia

Al-Awdah L.:
 Pediatric Infectious Diseases, Children’s Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia

Alghamdi J.:
 The Saudi Biobank, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

AlZahrani D.:
 Developmental Medicine Department, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

AlJohani S.:
 Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

Al-Afghani H.:
 Laboratory Department, Security Forces Hospital, General Directorate of Medical Services, Ministry of Interior, Riyadh, Saudi Arabia

Alrashed M.:
 Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia

AlDhawi N.:
 Developmental Medicine Department, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

AlBardis H.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alkwai S.:
 KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alswailm M.:
 KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Almalki F.:
 Developmental Medicine Department, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Albeladi M.:
 Developmental Medicine Department, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Almohammed I.:
 KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Barhoush E.:
 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Albader A.:
 Developmental Medicine Department, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Massadeh S.:
 Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

 Saudi Human Genome Project (SHGP), King Abdulaziz City for Science and Technology (KACST), Satellite Lab at King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

AlMalik A.:
 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 Life Science and Environmental Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alotaibi S.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Alghamdi B.:
 Department of Developmental Medicine, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

Jung J.:
 Titus Family Department of Clinical Pharmacy, USC School of Pharmacy University of Southern California, Los Angeles, CA, United States

Fawzy M.S.:
 Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

 King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia

Lee Y.:
 Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway

Magnus P.:
 Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway

Trogstad L.-I.S.:
 Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway

Helgeland Ø.:
 Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway

Harris J.R.:
 Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway

Mangino M.:
 Department of Twin Research and Genetic Epidemiology, King’s College London, London, United Kingdom

 NIHR Biomedical Research Centre at Guy’s and St Thomas’ Foundation Trust, London, United Kingdom

Spector T.D.:
 Department of Twin Research and Genetic Epidemiology, King’s College London, London, United Kingdom

Duncan E.:
 Department of Twin Research and Genetic Epidemiology, King’s College London, London, United Kingdom

Smieszek S.P.:
 Vanda Pharmaceuticals, London, United Kingdom

Przychodzen B.P.:
 Vanda Pharmaceuticals, London, United Kingdom

Polymeropoulos C.:
 Vanda Pharmaceuticals, London, United Kingdom

Polymeropoulos V.:
 Vanda Pharmaceuticals, London, United Kingdom

Polymeropoulos M.H.:
 Vanda Pharmaceuticals, London, United Kingdom

Fernandez-Cadenas I.:
 Stroke Pharmacogenomics and Genetics, Biomedical Research Institute Sant Pau, Sant Pau Hospital, Barcelona, Spain

Perez-Tur J.:
 Institute of Biomedicine of Valencia (IBV), National Spanish Research Council (CSIC), València, Spain

 Network Center for Biomedical Research on Neurodegenerative Diseases (CIBERNED), València, Spain

 Neurology and Genetic Mixed Unit, La Fe Health Research Institute, València, Spain

Llucià-Carol L.:
 Stroke Pharmacogenomics and Genetics, Biomedical Research Institute Sant Pau, Sant Pau Hospital, Barcelona, Spain

 Institute for Biomedical Research of Barcelona (IIBB), National Spanish Research Council (CSIC), Barcelona, Spain

Cullell N.:
 Stroke Pharmacogenomics and Genetics, Biomedical Research Institute Sant Pau, Sant Pau Hospital, Barcelona, Spain

 Department of Neurology, Hospital Universitari MútuaTerrassa, Fundació Docència i Recerca MútuaTerrassa, Terrassa, Spain

Muiño E.:
 Stroke Pharmacogenomics and Genetics, Biomedical Research Institute Sant Pau, Sant Pau Hospital, Barcelona, Spain

Cárcel-Márquez J.:
 Stroke Pharmacogenomics and Genetics, Biomedical Research Institute Sant Pau, Sant Pau Hospital, Barcelona, Spain

DeDiego M.L.:
 Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain

Iglesias L.L.:
 Instituto de Física de Cantabria (IFCA-CSIC), Santander, Spain

Planas A.M.:
 Institute for Biomedical Research of Barcelona (IIBB), National Spanish Research Council (CSIC), Barcelona, Spain

 Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

Soriano A.:
 Hospital Clínic, Barcelona, Spain

Rico V.:
 Hospital Clínic, Barcelona, Spain

Agüero D.:
 Hospital Clínic, Barcelona, Spain

Bedini J.L.:
 Hospital Clínic, Barcelona, Spain

Lozano F.:
 Hospital Clínic, IDIBAPS, School of Medicine, University of Barcelona, Barcelona, Spain

Domingo C.:
 Hospital Clínic, Barcelona, Spain

Robles V.:
 Hospital Clínic, Barcelona, Spain

Ruiz-Jaén F.:
 IDIBAPS, Barcelona, Spain

Márquez L.:
 IIBB-CSIC, Barcelona, Spain

Gomez J.:
 Servicio de Salud del Principado de Asturias, Oviedo, Spain

Coto E.:
 Servicio de Salud del Principado de Asturias, Oviedo, Spain

Albaiceta G.M.:
 Servicio de Salud del Principado de Asturias, Oviedo, Spain

García-Clemente M.:
 Servicio de Salud del Principado de Asturias, Oviedo, Spain

Dalmau D.:
 Hospital Mutua de Terrassa, Terrassa, Spain

Arranz M.J.:
 Hospital Mutua de Terrassa, Terrassa, Spain

Dietl B.:
 Hospital Mutua de Terrassa, Terrassa, Spain

Serra-Llovich A.:
 Hospital Mutua de Terrassa, Terrassa, Spain

Soler P.:
 Hospital Valle Hebrón, Barcelona, Spain

Colobrán R.:
 Hospital Valle Hebrón, Barcelona, Spain

Martín-Nalda A.:
 Hospital Valle Hebrón, Barcelona, Spain

Martínez A.P.:
 Hospital Valle Hebrón, Barcelona, Spain

Bernardo D.:
 Instituto de Biomedicina y Genética Molecular (IBGM), CSIC-Universidad de Valladolid, Valladolid, Spain

Rojo S.:
 Hospital Clínico Universitario de Valladolid (SACYL), Valladolid, Spain

Fiz-López A.:
 Instituto de Biomedicina y Genética Molecular (IBGM), CSIC-Universidad de Valladolid, Valladolid, Spain

Arribas E.:
 Instituto de Biomedicina y Genética Molecular (IBGM), CSIC-Universidad de Valladolid, Valladolid, Spain

de la Cal-Sabater P.:
 Instituto de Biomedicina y Genética Molecular (IBGM), CSIC-Universidad de Valladolid, Valladolid, Spain

Segura T.:
 University Hospital of Albacete, Albacete, Spain

González-Villa E.:
 University Hospital of Albacete, Albacete, Spain

Serrano-Heras G.:
 University Hospital of Albacete, Albacete, Spain

Martí-Fàbregas J.:
 Department of Neurology, Biomedical Research Institute Sant Pau (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

Jiménez-Xarrié E.:
 Department of Neurology, Biomedical Research Institute Sant Pau (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

de Felipe Mimbrera A.:
 Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain

Masjuan J.:
 Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain

García-Madrona S.:
 Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain

Domínguez-Mayoral A.:
 Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC and University of Seville, Seville, Spain

 Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain

Villalonga J.M.:
 Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC and University of Seville, Seville, Spain

 Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain

Menéndez-Valladares P.:
 Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, CSIC and University of Seville, Seville, Spain

 Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain

Chasman D.I.:
 Brigham and Women’s Hospital, Boston, MA, United States

 Harvard Medical School, Boston, MA, United States

Buring J.E.:
 Brigham and Women’s Hospital, Boston, MA, United States

 Harvard Medical School, Boston, MA, United States

Ridker P.M.:
 Brigham and Women’s Hospital, Boston, MA, United States

 Harvard Medical School, Boston, MA, United States

Franco G.:
 Brigham and Women’s Hospital, Boston, MA, United States

Sesso H.D.:
 Brigham and Women’s Hospital, Boston, MA, United States

 Harvard Medical School, Boston, MA, United States

Manson J.A.E.:
 Brigham and Women’s Hospital, Boston, MA, United States

 Harvard Medical School, Boston, MA, United States

Glessner J.R.:
 Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, United States

 Division of Human Genetics, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Hakonarson H.:
 Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, PA, United States

 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Medina-Gomez C.:
 Erasmus MC, Rotterdam, Netherlands

Uitterlinden A.G.:
 Erasmus MC, Rotterdam, Netherlands

Ikram M.A.:
 Erasmus MC, Rotterdam, Netherlands

Kristiansson K.:
 Finnish Institute for Health and Welfare (THL), Helsinki, Finland

Koskelainen S.:
 Finnish Institute for Health and Welfare (THL), Helsinki, Finland

Perola M.:
 Finnish Institute for Health and Welfare (THL), Helsinki, Finland

 University of Helsinki, Faculty of Medicine, Clinical and Molecular Metabolism Research Program, Helsinki, Finland

Donner K.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Kivinen K.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Palotie A.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Ripatti S.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland

Ruotsalainen S.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Kaunisto M.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Nakanishi T.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

 Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada

 Kyoto–McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

 Research Fellow, Japan Society for the Promotion of Science, Kyoto, Japan

Butler-Laporte G.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

 Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada

Forgetta V.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Morrison D.R.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Ghosh B.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Laurent L.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Belisle A.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Henry D.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Abdullah T.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Adeleye O.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Mamlouk N.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Kimchi N.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Afrasiabi Z.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Rezk N.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Vulesevic B.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Bouab M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Guzman C.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Petitjean L.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Tselios C.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Xue X.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Schurr E.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Afilalo J.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Afilalo M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Oliveira M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Brenner B.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Lepage P.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Ragoussis J.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Auld D.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Brassard N.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Durand M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Chassé M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Kaufmann D.E.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Lathrop G.M.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Mooser V.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Richards J.B.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Li R.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Adra D.:
 Department of Human Genetics, McGill University, Montréal, QC, Canada

Rahmouni S.:
 University of Liège, Liège, Belgium

Georges M.:
 University of Liège, Liège, Belgium

Moutschen M.:
 CHU of Liege, Liege, Belgium

Misset B.:
 University of Liège, Liège, Belgium

 CHU of Liege, Liege, Belgium

Darcis G.:
 University of Liège, Liège, Belgium

 CHU of Liege, Liege, Belgium

Guiot J.:
 University of Liège, Liège, Belgium

 CHU of Liege, Liege, Belgium

Guntz J.:
 CHU of Liege, Liege, Belgium

Azarzar S.:
 University of Liège, Liège, Belgium

 CHU of Liege, Liege, Belgium

Gofflot S.:
 CHU of Liege, Liege, Belgium

 5BHUL (Liege Biobank), CHU of Liege, Liege, Belgium

Beguin Y.:
 CHU of Liege, Liege, Belgium

 5BHUL (Liege Biobank), CHU of Liege, Liege, Belgium

Claassen S.:
 CHC Mont-Legia, Liege, Belgium

Malaise O.:
 CHU of Liege, Liege, Belgium

Huynen P.:
 CHU of Liege, Liege, Belgium

Meuris C.:
 CHU of Liege, Liege, Belgium

Thys M.:
 CHU of Liege, Liege, Belgium

Jacques J.:
 CHU of Liege, Liege, Belgium

Léonard P.:
 CHU of Liege, Liege, Belgium

Frippiat F.:
 CHU of Liege, Liege, Belgium

Giot J.-B.:
 CHU of Liege, Liege, Belgium

Sauvage A.-S.:
 CHU of Liege, Liege, Belgium

von Frenckell C.:
 CHU of Liege, Liege, Belgium

Belhaj Y.:
 University of Liège, Liège, Belgium

Lambermont B.:
 CHU of Liege, Liege, Belgium

Pigazzini S.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

Nkambule L.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Daya M.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Shortt J.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Rafaels N.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Wicks S.J.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Crooks K.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Barnes K.C.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Gignoux C.R.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Chavan S.:
 University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Laisk T.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Läll K.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Lepamets M.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Mägi R.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Esko T.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Reimann E.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Milani L.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Alavere H.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Metsalu K.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Puusepp M.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Metspalu A.:
 Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia

 University of Tartu, Tartu, Estonia

Naaber P.:
 University of Tartu, Tartu, Estonia

Laane E.:
 Kuressaare Hospital, Kuressaare, Estonia

 Tartu University Hospital, Tartu, Estonia

Pesukova J.:
 Kuressaare Hospital, Kuressaare, Estonia

Peterson P.:
 University of Tartu, Tartu, Estonia

 Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

Kisand K.:
 University of Tartu, Tartu, Estonia

 Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

Tabri J.:
 West Tallinn Central Hospital, Tallinn, Estonia

Allos R.:
 West Tallinn Central Hospital, Tallinn, Estonia

Hensen K.:
 West Tallinn Central Hospital, Tallinn, Estonia

Starkopf J.:
 Tartu University Hospital, Tartu, Estonia

Ringmets I.:
 Estonian Health Insurance Fund, Tallinn, Estonia

Tamm A.:
 Tartu University Hospital, Tartu, Estonia

Kallaste A.:
 Tartu University Hospital, Tartu, Estonia

Bochud P.-Y.:
 Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland

Rivolta C.:
 Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland

 Department of Ophthalmology, University of Basel, Basel, Switzerland

Bibert S.:
 Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland

Quinodoz M.:
 Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland

 Department of Ophthalmology, University of Basel, Basel, Switzerland

Kamdar D.:
 Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland

 Department of Ophthalmology, University of Basel, Basel, Switzerland

Boillat N.:
 Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland

Nussle S.G.:
 Centre for Primary Care and Public Health, University of Lausanne, Lausanne, Switzerland

Albrich W.:
 Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, St Gallen, Switzerland

Suh N.:
 Division of Intensive Care, Geneva University Hospitals and the University of Geneva Faculty of Medicine, Geneva, Switzerland

Neofytos D.:
 Infectious Disease Service, Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland

Erard V.:
 Clinique de Médecine et Spécialités, Infectiologie, HFR-Fribourg, Fribourg, Switzerland

Voide C.:
 Infectious Diseases Division, University Hospital Centre of the canton of Vaud, Hospital of Valais, Sion, Switzerland

de Cid R.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Galván-Femenía I.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Blay N.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Carreras A.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Cortés B.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Farré X.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Sumoy L.:
 GCAT-Genomes for Life, Germans Trias i Pujol Health Sciences Research Institute (IGTP), Badalona, Spain

Moreno V.:
 Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Consortium for Biomedical Research in Epidemiology and Public Health and University of Barcelona, Barcelona, Spain

Mercader J.M.:
 Massachusetts General Hospital, Boston, MA, United States

Guindo-Martinez M.:
 Life and Medical Sciences, Barcelona Supercomputing Center–Centro Nacional de Supercomputación (BSC-CNS), Barcelona, Spain

Torrents D.:
 Life and Medical Sciences, Barcelona Supercomputing Center–Centro Nacional de Supercomputación (BSC-CNS), Barcelona, Spain

Kogevinas M.:
 ISGlobal, Barcelona, Spain

 IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

Garcia-Aymerich J.:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

Castaño-Vinyals G.:
 ISGlobal, Barcelona, Spain

 IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

Dobaño C.:
 ISGlobal, Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

Renieri A.:
 Medical Genetics, University of Siena, Siena, Italy

 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Mari F.:
 Medical Genetics, University of Siena, Siena, Italy

 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Fallerini C.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Daga S.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Benetti E.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Baldassarri M.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Fava F.:
 Medical Genetics, University of Siena, Siena, Italy

 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Frullanti E.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Valentino F.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Doddato G.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Giliberti A.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Tita R.:
 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

Amitrano S.:
 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

Bruttini M.:
 Medical Genetics, University of Siena, Siena, Italy

 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Croci S.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Meloni I.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Mencarelli M.A.:
 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

Rizzo C.L.:
 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

Pinto A.M.:
 Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy

Beligni G.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Tommasi A.:
 Infectious Diseases Clinic, Department of Medicine 2, Azienda Ospedaliera di Perugia and University of Perugia, Santa Maria Hospital, Perugia, Italy

Di Sarno L.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Palmieri M.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Carriero M.L.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Alaverdian D.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Busani S.:
 Department of Anesthesia and Intensive Care, University of Modena and Reggio Emilia, Modena, Italy

Bruno R.:
 Division of Infectious Diseases and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

 Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy

Vecchia M.:
 Division of Infectious Diseases and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

Belli M.A.:
 U.O.C. Medicina, ASST Nord Milano, Ospedale Bassini, Milan, Italy

Picchiotti N.:
 Department of Mathematics, University of Pavia, Pavia, Italy

 University of Siena, DIISM-SAILAB, Siena, Italy

Sanarico M.:
 Independent researcher, Milan, Italy

Gori M.:
 University of Siena, DIISM-SAILAB, Siena, Italy

Furini S.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Mantovani S.:
 Division of Infectious Diseases and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

Ludovisi S.:
 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

Mondelli M.U.:
 Division of Infectious Diseases and Immunology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

 Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy

Castelli F.:
 Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy

Quiros-Roldan E.:
 Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy

Antoni M.D.:
 Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy

Zanella I.:
 Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy

 Clinical Chemistry Laboratory, Cytogenetics and Molecular Genetics Section, Diagnostic Department, ASST Spedali Civili di Brescia, Brescia, Italy

Vaghi M.:
 Chirurgia Vascolare, Ospedale Maggiore di Crema, Crema, Italy

Rusconi S.:
 III Infectious Diseases Unit, ASST-FBF-Sacco, Milan, Italy

 Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy

Siano M.:
 Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy

Montagnani F.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

 Department of Specialized and Internal Medicine, Tropical and Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy

Emiliozzi A.:
 HIV/AIDS Department, National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy

Fabbiani M.:
 Department of Specialized and Internal Medicine, Tropical and Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy

Rossetti B.:
 Department of Specialized and Internal Medicine, Tropical and Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy

Bargagli E.:
 Unit of Respiratory Diseases and Lung Transplantation, Department of Internal and Specialist Medicine, University of Siena, Siena, Italy

Bergantini L.:
 Unit of Respiratory Diseases and Lung Transplantation, Department of Internal and Specialist Medicine, University of Siena, Siena, Italy

D’Alessandro M.:
 Unit of Respiratory Diseases and Lung Transplantation, Department of Internal and Specialist Medicine, University of Siena, Siena, Italy

Cameli P.:
 Unit of Respiratory Diseases and Lung Transplantation, Department of Internal and Specialist Medicine, University of Siena, Siena, Italy

Bennett D.:
 Unit of Respiratory Diseases and Lung Transplantation, Department of Internal and Specialist Medicine, University of Siena, Siena, Italy

Anedda F.:
 Unit of Intensive Care Medicine. Departments of Emergency and Urgency, Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy

Marcantonio S.:
 Unit of Intensive Care Medicine. Departments of Emergency and Urgency, Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy

Scolletta S.:
 Unit of Intensive Care Medicine. Departments of Emergency and Urgency, Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy

Franchi F.:
 Unit of Intensive Care Medicine. Departments of Emergency and Urgency, Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy

Mazzei M.A.:
 Unit of Diagnostic Imaging, Departments of Medical, Surgical and Neurosciences and Radiological Sciences, University of Siena, Siena, Italy

Guerrini S.:
 Unit of Diagnostic Imaging, Departments of Medical, Surgical and Neurosciences and Radiological Sciences, University of Siena, Siena, Italy

Conticini E.:
 Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, Siena, Italy

Cantarini L.:
 Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, Siena, Italy

Frediani B.:
 Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, Siena, Italy

Tacconi D.:
 Infectious Diseases Unit, Department of Specialized and Internal Medicine, San Donato Hospital Arezzo, Arezzo, Italy

Spertilli C.:
 Infectious Diseases Unit, Department of Specialized and Internal Medicine, San Donato Hospital Arezzo, Arezzo, Italy

Feri M.:
 Anesthesia Unit, Department of Emergency, San Donato Hospital, Arezzo, Italy

Donati A.:
 Anesthesia Unit, Department of Emergency, San Donato Hospital, Arezzo, Italy

Scala R.:
 Pneumology Unit and UTIP, Department of Specialized and Internal Medicine, San Donato Hospital, Arezzo, Italy

Guidelli L.:
 Pneumology Unit and UTIP, Department of Specialized and Internal Medicine, San Donato Hospital, Arezzo, Italy

Spargi G.:
 Anesthesia Unit, Department of Emergency, Misericordia Hospital, Grosseto, Italy

Corridi M.:
 Anesthesia Unit, Department of Emergency, Misericordia Hospital, Grosseto, Italy

Nencioni C.:
 Infectious Diseases Unit, Department of Specialized and Internal Medicine, Misericordia Hospital, Grosseto, Italy

Croci L.:
 Infectious Diseases Unit, Department of Specialized and Internal Medicine, Misericordia Hospital, Grosseto, Italy

Bandini M.:
 Department of Preventive Medicine, Azienda USL Toscana Sud Est, Tuscany, Italy

Caldarelli G.P.:
 Clinical Chemical Analysis Laboratory, Misericordia Hospital, Grosseto, Italy

Piacentini P.:
 Department of Preventive Medicine, Azienda USL Toscana Sud Est, Tuscany, Italy

Desanctis E.:
 Department of Preventive Medicine, Azienda USL Toscana Sud Est, Tuscany, Italy

Cappelli S.:
 Department of Preventive Medicine, Azienda USL Toscana Sud Est, Tuscany, Italy

Canaccini A.:
 Territorial Scientific Technician Department, Azienda USL Toscana Sud Est, Arezzo, Italy

Verzuri A.:
 Territorial Scientific Technician Department, Azienda USL Toscana Sud Est, Arezzo, Italy

Anemoli V.:
 Territorial Scientific Technician Department, Azienda USL Toscana Sud Est, Arezzo, Italy

Ognibene A.:
 Clinical Chemical Analysis Laboratory, San Donato Hospital, Arezzo, Italy

Pancrazzi A.:
 Clinical Chemical Analysis Laboratory, San Donato Hospital, Arezzo, Italy

Lorubbio M.:
 Clinical Chemical Analysis Laboratory, San Donato Hospital, Arezzo, Italy

D’Arminio Monforte A.:
 Department of Health Sciences, Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy

Miraglia F.G.:
 Department of Health Sciences, Clinic of Infectious Diseases, ASST Santi Paolo e Carlo, University of Milan, Milan, Italy

Girardis M.:
 Department of Anesthesia and Intensive Care, University of Modena and Reggio Emilia, Modena, Italy

Venturelli S.:
 Department of Anesthesia and Intensive Care, University of Modena and Reggio Emilia, Modena, Italy

Cossarizza A.:
 Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy

Antinori A.:
 HIV/AIDS Department, National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy

Vergori A.:
 HIV/AIDS Department, National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy

Gabrieli A.:
 Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy

Riva A.:
 III Infectious Diseases Unit, ASST-FBF-Sacco, Milan, Italy

 Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy

Francisci D.:
 Infectious Diseases Clinic, Department of Medicine 2, Azienda Ospedaliera di Perugia and University of Perugia, Santa Maria Hospital, Perugia, Italy

 Infectious Diseases Clinic, Santa Maria Hospital, University of Perugia, Perugia, Italy

Schiaroli E.:
 Infectious Diseases Clinic, Department of Medicine 2, Azienda Ospedaliera di Perugia and University of Perugia, Santa Maria Hospital, Perugia, Italy

 Infectious Diseases Clinic, Santa Maria Hospital, University of Perugia, Perugia, Italy

Paciosi F.:
 Infectious Diseases Clinic, Santa Maria Hospital, University of Perugia, Perugia, Italy

Scotton P.G.:
 Department of Infectious Diseases, Treviso Hospital, Treviso, Italy

Andretta F.:
 Department of Infectious Diseases, Treviso Hospital, Treviso, Italy

Panese S.:
 Clinical Infectious Diseases, Mestre Hospital, Venezia, Italy

Scaggiante R.:
 Infectious Diseases Clinic, Belluno, Italy

Gatti F.:
 Infectious Diseases Clinic, Belluno, Italy

Parisi S.G.:
 Department of Molecular Medicine, University of Padova, Padua, Italy

Baratti S.:
 Department of Molecular Medicine, University of Padova, Padua, Italy

Della Monica M.:
 Medical Genetics and Laboratory of Medical Genetics Unit, A.O.R.N. Antonio Cardarelli Hospital, Naples, Italy

Piscopo C.:
 Medical Genetics and Laboratory of Medical Genetics Unit, A.O.R.N. Antonio Cardarelli Hospital, Naples, Italy

Capasso M.:
 Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy

 CEINGE Biotecnologie Avanzate, Naples, Italy

 IRCCS SDN, Naples, Italy

Russo R.:
 Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy

 CEINGE Biotecnologie Avanzate, Naples, Italy

Andolfo I.:
 Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy

 CEINGE Biotecnologie Avanzate, Naples, Italy

Iolascon A.:
 Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy

 CEINGE Biotecnologie Avanzate, Naples, Italy

Fiorentino G.:
 Unit of Respiratory Physiopathology, AORN dei Colli, Monaldi Hospital, Naples, Italy

Carella M.:
 Division of Medical Genetics, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Castori M.:
 Division of Medical Genetics, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Merla G.:
 Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy

 Laboratory of Regulatory and Functional Genomics, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Squeo G.M.:
 Laboratory of Regulatory and Functional Genomics, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Aucella F.:
 Department of Medical Sciences, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Raggi P.:
 Clinical Trial Office, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Marciano C.:
 Clinical Trial Office, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Perna R.:
 Clinical Trial Office, Fondazione IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy

Bassetti M.:
 Department of Health Sciences, University of Genova, Genova, Italy

 Infectious Diseases Clinic, Policlinico San Martino Hospital, IRCCS for Cancer Research, Genova, Italy

Di Biagio A.:
 Infectious Diseases Clinic, Policlinico San Martino Hospital, IRCCS for Cancer Research, Genova, Italy

Sanguinetti M.:
 Microbiology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Medicine, Rome, Italy

 Department of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

Masucci L.:
 Microbiology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Medicine, Rome, Italy

 Department of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

Valente S.:
 Department of Cardiovascular Diseases, University of Siena, Siena, Italy

Mandalà M.:
 Otolaryngology Unit, University of Siena, Siena, Italy

Giorli A.:
 Otolaryngology Unit, University of Siena, Siena, Italy

Salerni L.:
 Otolaryngology Unit, University of Siena, Siena, Italy

Zucchi P.:
 Department of Internal Medicine, ASST Valtellina e Alto Lario, Sondrio, Italy

Parravicini P.:
 Department of Internal Medicine, ASST Valtellina e Alto Lario, Sondrio, Italy

Menatti E.:
 Oncologia Medica e Ufficio Flussi Sondrio, Sondrio, Italy

Trotta T.:
 First Aid Department, Luigi Curto Hospital, Polla, Salerno, Italy

Giannattasio F.:
 First Aid Department, Luigi Curto Hospital, Polla, Salerno, Italy

Coiro G.:
 First Aid Department, Luigi Curto Hospital, Polla, Salerno, Italy

Lena F.:
 Local Health Unit, Pharmaceutical Department of Grosseto, Toscana Sud Est Local Health Unit, Grosseto, Italy

Coviello D.A.:
 U.O.C. Laboratorio di Genetica Umana, IRCCS Istituto Giannina Gaslini, Genoa, Italy

Mussini C.:
 Infectious Diseases Clinics, University of Modena and Reggio Emilia, Modena, Italy

Martinelli E.:
 Department of Respiratory Diseases, Azienda Ospedaliera di Cremona, Cremona, Italy

Mancarella S.:
 U.O.C. Medicina, ASST Nord Milano, Ospedale Bassini, Milan, Italy

Tavecchia L.:
 U.O.C. Medicina, ASST Nord Milano, Ospedale Bassini, Milan, Italy

Crotti L.:
 Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, San Luca Hospital, Milan, Italy

 Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

 Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano, IRCCS, Milan, Italy

Gabbi C.:
 Independent researcher, Milan, Italy

Rizzi M.:
 Unit of Infectious Diseases, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy

Maggiolo F.:
 Unit of Infectious Diseases, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy

Ripamonti D.:
 Unit of Infectious Diseases, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy

Bachetti T.:
 Direzione Scientifica, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy

La Rovere M.T.:
 Department of Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Pavia, Italy

Sarzi-Braga S.:
 Department of Cardiac Rehabilitation, Institute of Tradate (VA) and Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy

Bussotti M.:
 Department of Cardiology, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Milan, Milan, Italy

Ceri S.:
 Department of Electronics, Information and Bioengineering (DEIB), Politecnico di Milano, Milan, Italy

Pinoli P.:
 Department of Electronics, Information and Bioengineering (DEIB), Politecnico di Milano, Milan, Italy

Raimondi F.:
 Scuola Normale Superiore, Pisa, Italy

Biscarini F.:
 CNR-Consiglio Nazionale delle Ricerche, Istituto di Biologia e Biotecnologia Agraria (IBBA), Milano, Italy

Stella A.:
 CNR-Consiglio Nazionale delle Ricerche, Istituto di Biologia e Biotecnologia Agraria (IBBA), Milano, Italy

Zguro K.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Capitani K.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

 Core Research Laboratory, ISPRO, Florence, Italy

Suardi C.:
 Fondazione per la Ricerca Ospedale di Bergamo, Bergamo, Italy

Dei S.:
 Health Management, Azienda USL Toscana Sud Est, Tuscany, Italy

Parati G.:
 Department of Cardiovascular, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, San Luca Hospital, Milan, Italy

 Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

Ravaglia S.:
 IRCCS Mondino Foundation, Pavia, Italy

Artuso R.:
 Medical Genetics Unit, Meyer Children’s University Hospital, Florence, Italy

Bottà G.:
 Allelica, New York, NY, United States

Di Domenico P.:
 Allelica, New York, NY, United States

Rancan I.:
 Department of Specialized and Internal Medicine, Tropical and Infectious Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy

Perrella A.:
 Pneumology Unit, Department of Medicine, Misericordia Hospital, Grosseto, Italy

Bianchi F.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

 Pneumology Unit, Department of Medicine, Misericordia Hospital, Grosseto, Italy

Romani D.:
 Department of Preventive Medicine, Azienda USL Toscana Sud Est, Tuscany, Italy

Bergomi P.:
 Intensive Care Unit and Department of Anesthesia, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Polo Universitario, University of Milan, Milan, Italy

Catena E.:
 Intensive Care Unit and Department of Anesthesia, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Polo Universitario, University of Milan, Milan, Italy

Colombo R.:
 Intensive Care Unit and Department of Anesthesia, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Polo Universitario, University of Milan, Milan, Italy

Tanfoni M.:
 University of Siena, DIISM-SAILAB, Siena, Italy

Vincenti A.:
 Infectious Disease Unit, Hospital of Massa, Massa, Italy

Ferri C.:
 Department of Clinical Medicine, Public Health, Life and Environment Sciences, University of L’Aquila, L’Aquila, Italy

Grassi D.:
 Department of Clinical Medicine, Public Health, Life and Environment Sciences, University of L’Aquila, L’Aquila, Italy

Pessina G.:
 UOSD Laboratorio di Genetica Medica—ASL Viterbo, San Lorenzo, Italy

Tumbarello M.:
 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

 Department of Medical Sciences, Infectious and Tropical Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy

Di Pietro M.:
 Unit of Infectious Diseases, Santa Maria Annunziata Hospital, Florence, Italy

Sabrina R.:
 IRCCS Mondino Foundation, Pavia, Italy

Luchi S.:
 Infectious Disease Unit, Hospital of Lucca, Lucca, Italy

Barbieri C.:
 Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Acquilini D.:
 Infectious Disease Unit, Santo Stefano Hospital, AUSL Toscana Centro, Prato, Italy

Andreucci E.:
 Medical Genetics Unit, Meyer Children’s University Hospital, Florence, Italy

Segala F.V.:
 Clinic of Infectious Diseases, Catholic University of the Sacred Heart, Rome, Italy

Tiseo G.:
 Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Falcone M.:
 Infectious Diseases Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

Lista M.:
 Medical Genetics, University of Siena, Siena, Italy

 Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy

Poscente M.:
 UOSD Laboratorio di Genetica Medica—ASL Viterbo, San Lorenzo, Italy

De Vivo O.:
 Department of Cardiovascular Diseases, University of Siena, Siena, Italy

Petrocelli P.:
 Infectious Disease Unit, Hospital of Lucca, Lucca, Italy

Guarnaccia A.:
 Microbiology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Medicine, Rome, Italy

Baroni S.:
 Department of Diagnostic and Laboratory Medicine, Institute of Biochemistry and Clinical Biochemistry, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy

Smith A.V.:
 University of Michigan, Ann Arbor, MI, United States

Boughton A.P.:
 University of Michigan, Ann Arbor, MI, United States

Li K.W.:
 University of Michigan, Ann Arbor, MI, United States

LeFaive J.:
 University of Michigan, Ann Arbor, MI, United States

Annis A.:
 University of Michigan, Ann Arbor, MI, United States

Justice A.E.:
 Department of Population Health Sciences, Geisinger Health System, Danville, PA, United States

Mirshahi T.:
 Geisinger, Danville, PA, United States

Chittoor G.:
 Department of Population Health Sciences, Geisinger Health System, Danville, PA, United States

Josyula N.S.:
 Department of Population Health Sciences, Geisinger Health System, Danville, PA, United States

Kosmicki J.A.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Ferreira M.A.R.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Leader J.B.:
 Phenomic Analytics and Clinical Data Core, Geisinger Health System, Danville, PA, United States

Carey D.J.:
 Department of Molecular and Functional Genomics, Geisinger Health System, Danville, PA, United States

Gass M.C.:
 Phenomic Analytics and Clinical Data Core, Geisinger Health System, Danville, PA, United States

Horowitz J.E.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Cantor M.N.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Yadav A.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Baras A.:
 Regeneron Genetics Center, Tarrytown, NY, United States

Abecasis G.R.:
 Regeneron Genetics Center, Tarrytown, NY, United States

van Heel D.A.:
 Queen Mary University of London, London, United Kingdom

Hunt K.A.:
 Queen Mary University of London, London, United Kingdom

Mason D.:
 Bradford Institute for Health Research, Bradford Teaching Hospitals National Health Service (NHS) Foundation Trust, Bradford, United Kingdom

Huang Q.Q.:
 Medical and Population Genomics, Wellcome Sanger Institute, Hinxton, United Kingdom

Finer S.:
 Queen Mary University of London, London, United Kingdom

Trivedi B.:
 Queen Mary University of London, London, United Kingdom

Griffiths C.J.:
 Queen Mary University of London, London, United Kingdom

Martin H.C.:
 Medical and Population Genomics, Wellcome Sanger Institute, Hinxton, United Kingdom

Wright J.:
 Bradford Institute for Health Research, Bradford Teaching Hospitals National Health Service (NHS) Foundation Trust, Bradford, United Kingdom

Trembath R.C.:
 School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom

Soranzo N.:
 Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom

 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

 Department of Haematology, University of Cambridge, Cambridge, United Kingdom

Zhao J.H.:
 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Butterworth A.S.:
 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom

 Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom

Danesh J.:
 Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom

 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom

 Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom

Di Angelantonio E.:
 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

 British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom

 Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom

Franke L.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Boezen M.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Deelen P.:
 Department of Genetics, University Medical Centre Utrecht, Utrecht, Netherlands

Claringbould A.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Lopera E.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Warmerdam R.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Vonk J.M.:
 Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

van Blokland I.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Lanting P.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

Ori A.P.S.:
 Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands

 Department of Psychiatry, University Medical Center Groningen, Groningen, Netherlands

Zöllner S.:
 University of Michigan, Ann Arbor, MI, United States

Wang J.:
 University of Michigan, Ann Arbor, MI, United States

Beck A.:
 University of Michigan, Ann Arbor, MI, United States

Peloso G.:
 Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States

 Center for Population Genomics, MAVERIC, VA Boston Healthcare System, Boston, MA, United States

 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

Ho Y.-L.:
 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

Sun Y.V.:
 Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, United States

Huffman J.E.:
 Center for Population Genomics, MAVERIC, VA Boston Healthcare System, Boston, MA, United States

 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

O’Donnell C.J.:
 Center for Population Genomics, MAVERIC, VA Boston Healthcare System, Boston, MA, United States

 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

Cho K.:
 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

Tsao P.:
 Stanford University, Stanford, CA, United States

Gaziano J.M.:
 MAVERIC, VA Boston Healthcare System, Boston, MA, United States

Nivard M.:
 Vrije Universiteit Amsterdam, Amsterdam, Netherlands

de Geus E.:
 Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Bartels M.:
 Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Jan Hottenga J.:
 Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Weiss S.T.:
 Brigham and Women’s Hospital, Boston, MA, United States

Karlson E.W.:
 Brigham and Women’s Hospital, Boston, MA, United States

Smoller J.W.:
 Massachusetts General Hospital, Boston, MA, United States

Green R.C.:
 Broad Institute of MIT and Harvard, Boston, MA, United States

Feng Y.-C.A.:
 Massachusetts General Hospital, Boston, MA, United States

Mercader J.:
 Massachusetts General Hospital, Boston, MA, United States

Murphy S.N.:
 Massachusetts General Hospital, Boston, MA, United States

Meigs J.B.:
 Massachusetts General Hospital, Boston, MA, United States

Woolley A.E.:
 Brigham and Women’s Hospital, Boston, MA, United States

Perez E.F.:
 Massachusetts General Hospital, Boston, MA, United States

Rader D.:
 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Verma A.:
 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Ritchie M.D.:
 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

Li B.:
 Stanford University, Stanford, CA, United States

Verma S.S.:
 Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States

Lucas A.:
 Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States

Bradford Y.:
 Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States

Zeberg H.:
 Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden

 Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

Frithiof R.:
 Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

Hultström M.:
 Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

 Integrative Physiology, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

Lipcsey M.:
 Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

Nkambul L.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Tardif N.:
 Division Anesthesiology and Intensive Care, CLINTEC, Karolinska Institutet, Stockholm, Sweden

Rooyackers O.:
 Division Anesthesiology and Intensive Care, CLINTEC, Karolinska Institutet, Stockholm, Sweden

Grip J.:
 Division Anesthesiology and Intensive Care, CLINTEC, Karolinska Institutet, Stockholm, Sweden

Maricic T.:
 Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

Karczewski K.J.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Atkinson E.G.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Tsuo K.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Baya N.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Turley P.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Gupta R.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Callier S.:
 Department of Clinical Research and Leadership, George Washington University, Washington, DC, United States

Walters R.K.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Palmer D.S.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Sarma G.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Cheng N.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Lu W.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Bryant S.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Churchhouse C.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Cusick C.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Goldstein J.I.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

King D.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Seed C.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Finucane H.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Martin A.R.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Satterstrom F.K.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

 Massachusetts General Hospital, Boston, MA, United States

Wilson D.J.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Armstrong J.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Rudkin J.K.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Band G.:
 Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Earle S.G.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Lin S.-K.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Arning N.:
 Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

Crook D.W.:
 Nuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Wyllie D.H.:
 Public Health England, Field Service, Addenbrooke’s Hospital, Cambridge, United Kingdom

O’Connell A.M.:
 Public Health England, Data and Analytical Services, National Infection Service, London, United Kingdom

Spencer C.C.A.:
 Genomics PLC, Oxford, United Kingdom

Koelling N.:
 Genomics PLC, Oxford, United Kingdom

Fowler T.:
 Genomics England, London, United Kingdom

 Test and Trace, the Health Security Agency, Department of Health and Social Care, London, United Kingdom

Kousathanas A.:
 Genomics England, London, United Kingdom

Pasko D.:
 Genomics England, London, United Kingdom

Walker S.:
 Genomics England, London, United Kingdom

Rendon A.:
 Genomics England, London, United Kingdom

Stuckey A.:
 Genomics England, London, United Kingdom

Odhams C.A.:
 Genomics England, London, United Kingdom

Rhodes D.:
 Genomics England, London, United Kingdom

Chan G.:
 Genomics England, London, United Kingdom

Arumugam P.:
 Genomics England, London, United Kingdom

Ball C.A.:
 Ancestry, Lehi, UT, United States

Hong E.L.:
 Ancestry, Lehi, UT, United States

Rand K.:
 Ancestry, Lehi, UT, United States

Girshick A.:
 Ancestry, Lehi, UT, United States

Guturu H.:
 Ancestry, Lehi, UT, United States

Baltzell A.H.:
 Ancestry, Lehi, UT, United States

Roberts G.:
 Ancestry, Lehi, UT, United States

Park D.:
 Ancestry, Lehi, UT, United States

Coignet M.:
 Ancestry, Lehi, UT, United States

McCurdy S.:
 Ancestry, Lehi, UT, United States

Knight S.:
 Ancestry, Lehi, UT, United States

Partha R.:
 Ancestry, Lehi, UT, United States

Rhead B.:
 Ancestry, Lehi, UT, United States

Zhang M.:
 Ancestry, Lehi, UT, United States

Berkowitz N.:
 Ancestry, Lehi, UT, United States

Gaddis M.:
 Ancestry, Lehi, UT, United States

Noto K.:
 Ancestry, Lehi, UT, United States

Ruiz L.:
 Ancestry, Lehi, UT, United States

Pavlovic M.:
 Ancestry, Lehi, UT, United States

Sloofman L.G.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Charney A.W.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Beckmann N.D.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Schadt E.E.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Jordan D.M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Thompson R.C.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Gettler K.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Abul-Husn N.S.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Ascolillo S.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Buxbaum J.D.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Chaudhary K.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Cho J.H.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Itan Y.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Kenny E.E.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Belbin G.M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Sealfon S.C.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Sebra R.P.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Salib I.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Collins B.L.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Levy T.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Britvan B.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Keller K.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Tang L.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Peruggia M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Hiester L.L.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Niblo K.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Aksentijevich A.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Labkowsky A.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Karp A.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Zlatopolsky M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Preuss M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Loos R.J.F.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Nadkarni G.N.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Do R.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Hoggart C.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Choi S.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Underwood S.J.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

O’Reilly P.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Huckins L.M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Zyndorf M.:
 Icahn School of Medicine at Mount Sinai, New York, NY, United States

Daly M.J.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Neale B.M.:
 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Ganna A.:
 Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

 Broad Institute of MIT and Harvard, Cambridge, MA, United States

Fawkes A.:
 Edinburgh Clinical Research Facility, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom

Murphy L.:
 Edinburgh Clinical Research Facility, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom

Rowan K.:
 Intensive Care National Audit and Research Centre, London, United Kingdom

Ponting C.P.:
 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Vitart V.:
 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Wilson J.F.:
 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Yang J.:
 School of Life Sciences, Westlake University, Hangzhou, China

 Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China

Bretherick A.D.:
 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Scott R.H.:
 Genomics England, London, United Kingdom

Hendry S.C.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Moutsianas L.:
 Genomics England, London, United Kingdom

Law A.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

Caulfield M.J.:
 Genomics England, London, United Kingdom

Baillie J.K.:
 Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

 MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

 Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

 Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

 Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom