Prevalence of acquired AmpC beta-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes at a Spanish hospital from 1999 to 2007
Por:
Mata, C, Miro, E, Rivera, A, Mirelis, B, Coll, P, Navarro, F
Publicada:
1 may 2010
Resumen:
P>In 2007, a significant increase in acquired ampC genes in Enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. Proteus mirabilis showed the highest prevalence (0.95%) and CMY-2 was the most prevalent AmpC enzyme (66.7%). Other enzymes such as CMY-4, DHA-1, ACC-1, and three new enzymes called CMY-25, CMY-27 and CMY-40 were detected. Seven out of the 117 isolates (6%) also produced an extended-spectrum beta-lactamase. As acquired AmpC enzymes are likely to become a serious public health issue worldwide, close surveillance is necessary to curb their spread.
Filiaciones:
Mata, C:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Univ Autonoma Barcelona, Unitat Microbiol, Dept Genet & Microbiol, Bellaterra, Spain
Miro, E:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Rivera, A:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Univ Autonoma Barcelona, Unitat Microbiol, Dept Genet & Microbiol, Bellaterra, Spain
Mirelis, B:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Coll, P:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Univ Autonoma Barcelona, Unitat Microbiol, Dept Genet & Microbiol, Bellaterra, Spain
Navarro, F:
Hosp Santa Creu & Sant Pau, Microbiol Serv, Barcelona, Spain
Univ Autonoma Barcelona, Unitat Microbiol, Dept Genet & Microbiol, Bellaterra, Spain
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