Soy Aeroallergens in Thoracic Fraction Particles (PM10)
Por:
Gomez-Olles, S, Untoria, MD, Villalbi, JR, Munoz, X, Morell, F, Cruz, MJ
Publicada:
1 ene 2013
Resumen:
Background: The aerodynamic diameter of biological particles determines their ability to penetrate the human respiratory system.
Objective: To assess the content of allergens less than 10 mu m in diameter in the particle fraction of airborne dust in order to improve control of exposure to harmful soybean aeroallergens.
Methods: In this study, 98 pairs of particulate matter measuring less than 10 mu m in diameter (PM10) and total suspended particulate (TSP) filters were collected in parallel and analyzed for soy aeroallergens by the inhibition enzyme-linked immunosorbent assay.
Results: The median levels found were 6 and 22.5 U/m(3) for PM10 and TSP filters, respectively. A good correlation was found between soy aeroallergen content in PM10 and TSP filters. The median proportion of soy aeroallergen content in PM10 filters versus TSP filters was 28.6%, and varied widely across different days.
Conclusions: Due to this wide variation between days, it seems that soy aeroallergen content in TSP filters is not a good surrogate of soy allergen content in PM10 filters. Further clinical studies should be conducted to assess differences in the health impact of soy allergen content in PM10 filters and TSP filters.
Filiaciones:
Gomez-Olles, S:
Hosp Univ Vail Hebron, Serv Neumol, Barcelona 08035, Spain
Untoria, MD:
Hosp Univ Vail Hebron, Serv Neumol, Barcelona 08035, Spain
Villalbi, JR:
Agenda Salut Publ Barcelona, Barcelona, Spain
CIBERESP, Barcelona, Spain
Inst Invest Biomed St Pau, Barcelona, Spain
Munoz, X:
Hosp Univ Vail Hebron, Serv Neumol, Barcelona 08035, Spain
Univ Autonoma Barcelona, Dept Biol Cellular Fisiol & Immunol, E-08193 Barcelona, Spain
Morell, F:
Hosp Univ Vail Hebron, Serv Neumol, Barcelona 08035, Spain
Cruz, MJ:
Hosp Univ Vail Hebron, Serv Neumol, Barcelona 08035, Spain
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