Hypoglycemia associated with fluoxetine treatment in a patient with type 1 diabetes
Por:
Biagetti, B, Corcoy, R
Publicada:
16 ago 2013
Resumen:
We report on a patient with type 1 diabetes mellitus who presented with recurrent episodes of hypoglycemia and a marked reduction in her daily insulin requirements after introduction of fluoxetine. This 25-year-old Caucasian woman had been followed up at the outpatient clinic for type 1 diabetes mellitus and pre-pregnancy care. She used a continuous subcutaneous insulin infusion with lispro and her daily insulin dose was 0.5 IU/kg per day. She had no chronic diabetic complications or hypoglycemia unawareness. Fluoxetine at a daily dose of 20 mg had been started because of depressive symptoms and within one week, she presented recurrent hypoglycemic episodes that prompted a progressive reduction in the insulin dose down to 0.3 IU/kg per day. The reduced insulin requirements continued during the period of fluoxetine treatment while glycated hemoglobin remained stable. She had no concurrent additional cause to explain the reduced insulin requirements. After fluoxetine was stopped, insulin requirements progressively increased and returned to the patients usual dose. (C) 2013 Baishideng. All rights reserved.
Filiaciones:
Biagetti, B:
Hosp Santa Creu & Sant Pau, Serv Endocrinol & Nutr, Avgda St Antoni M Claret 167, Barcelona 08025, Spain
Corcoy, R:
Hosp Santa Creu & Sant Pau, Serv Endocrinol & Nutr, Avgda St Antoni M Claret 167, Barcelona 08025, Spain
Univ Autonoma Barcelona, Dept Med, Belllaterra 08193, Spain
Inst Salud Carlos III, CIBER Bioengn Biomat & Nanotechnol, Madrid 28029, Spain
Green Published, hybrid
|